Combination effect of argan oil and low frequency electromagnetic field on open wound in mice

This study was conducted to evaluate the effect of argan oil with the exposure of low frequency electromagnetic field (EMF) on open wound healing in mice. Eighteen male mice (20-40 g) were divided into three groups: phosphate buffer saline (PBS) as negative control, solcoseryl gel as positive contro...

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Main Authors:	Siti Fathiah Masre, Muzamir M.K., Sabarina I., Jehan N., Yanti Rosli
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/12939/ http://journalarticle.ukm.my/12939/ http://journalarticle.ukm.my/12939/1/24000-76977-1-PB.pdf

id	ukm-12939
recordtype	eprints
spelling	ukm-129392019-05-17T14:37:06Z http://journalarticle.ukm.my/12939/ Combination effect of argan oil and low frequency electromagnetic field on open wound in mice Siti Fathiah Masre, Muzamir M.K., Sabarina I., Jehan N., Yanti Rosli, This study was conducted to evaluate the effect of argan oil with the exposure of low frequency electromagnetic field (EMF) on open wound healing in mice. Eighteen male mice (20-40 g) were divided into three groups: phosphate buffer saline (PBS) as negative control, solcoseryl gel as positive control, and argan oil with the exposure of low frequency EMF, 1.2 mT (treatment group). Full thickness wounds (4 mm diameter) were induced on the shaved dorsal of the mouse. All mice were sacrificed on day 12 after the final treatment. Macroscopic observation, wound contraction rate, histopathology analysis and total protein content were examined in this study. Results showed that wounds treated with argan oil and exposed to low frequency EMF has a significant increase in wound contraction rate (p < 0.05) and total protein content (p < 0.05). Moreover, histopathological analysis on the wound tissues displayed complete re-epithelization with thick and dense collagen fibers in the argan oil with low frequency EMF exposure treated group. In conclusion, topical treatment of argan oil with low frequency EMF exposure yield a better healing progress and showed the ability to accelerate wound healing. Penerbit Universiti Kebangsaan Malaysia 2018 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12939/1/24000-76977-1-PB.pdf Siti Fathiah Masre, and Muzamir M.K., and Sabarina I., and Jehan N., and Yanti Rosli, (2018) Combination effect of argan oil and low frequency electromagnetic field on open wound in mice. Jurnal Sains Kesihatan Malaysia, 16 (SI). pp. 41-45. ISSN 1675-8161 http://ejournal.ukm.my/jskm/issue/view/1072
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	This study was conducted to evaluate the effect of argan oil with the exposure of low frequency electromagnetic field (EMF) on open wound healing in mice. Eighteen male mice (20-40 g) were divided into three groups: phosphate buffer saline (PBS) as negative control, solcoseryl gel as positive control, and argan oil with the exposure of low frequency EMF, 1.2 mT (treatment group). Full thickness wounds (4 mm diameter) were induced on the shaved dorsal of the mouse. All mice were sacrificed on day 12 after the final treatment. Macroscopic observation, wound contraction rate, histopathology analysis and total protein content were examined in this study. Results showed that wounds treated with argan oil and exposed to low frequency EMF has a significant increase in wound contraction rate (p < 0.05) and total protein content (p < 0.05). Moreover, histopathological analysis on the wound tissues displayed complete re-epithelization with thick and dense collagen fibers in the argan oil with low frequency EMF exposure treated group. In conclusion, topical treatment of argan oil with low frequency EMF exposure yield a better healing progress and showed the ability to accelerate wound healing.
format	Article
author	Siti Fathiah Masre, Muzamir M.K., Sabarina I., Jehan N., Yanti Rosli,
spellingShingle	Siti Fathiah Masre, Muzamir M.K., Sabarina I., Jehan N., Yanti Rosli, Combination effect of argan oil and low frequency electromagnetic field on open wound in mice
author_facet	Siti Fathiah Masre, Muzamir M.K., Sabarina I., Jehan N., Yanti Rosli,
author_sort	Siti Fathiah Masre,
title	Combination effect of argan oil and low frequency electromagnetic field on open wound in mice
title_short	Combination effect of argan oil and low frequency electromagnetic field on open wound in mice
title_full	Combination effect of argan oil and low frequency electromagnetic field on open wound in mice
title_fullStr	Combination effect of argan oil and low frequency electromagnetic field on open wound in mice
title_full_unstemmed	Combination effect of argan oil and low frequency electromagnetic field on open wound in mice
title_sort	combination effect of argan oil and low frequency electromagnetic field on open wound in mice
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2018
url	http://journalarticle.ukm.my/12939/ http://journalarticle.ukm.my/12939/ http://journalarticle.ukm.my/12939/1/24000-76977-1-PB.pdf
first_indexed	2023-09-18T20:03:44Z
last_indexed	2023-09-18T20:03:44Z
_version_	1777407019472388096

Combination effect of argan oil and low frequency electromagnetic field on open wound in mice

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