Good anatomical outcome of orbital plasmacytoma following chemo-radiotherapy

Extramedullary plasmacytoma is a rare complication from multiple myeloma. We report a 56-year-old lady with underlying multiple myeloma who developed swelling over the left eye. It caused a non-axial proptosis, exposure keratopathy and visual acuity of counting fingers. A tissue biopsy revealed infi...

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Bibliographic Details
Main Authors: Aimy Mastura ZY, Othmaliza Othman, Khairunisa AA, Norshamsiah Md. Din
Format: Article
Language:English
Published: Pusat Perubatan Universiti Kebangsaan Malaysia 2017
Online Access:http://journalarticle.ukm.my/12696/
http://journalarticle.ukm.my/12696/
http://journalarticle.ukm.my/12696/1/19_aimy_et_al_pdf_71337.pdf
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Summary:Extramedullary plasmacytoma is a rare complication from multiple myeloma. We report a 56-year-old lady with underlying multiple myeloma who developed swelling over the left eye. It caused a non-axial proptosis, exposure keratopathy and visual acuity of counting fingers. A tissue biopsy revealed infiltration of tissue fragments with neoplastic plasma cells positive for CD138 and Kappa light chain restrictions consistent with plasmacytoma. Following radio-chemotherapy, the mass shrunk tremendously but her visual outcome remained poor.