Olive and its phenolic compound as the promising neuroprotective agent

Recent progress in alternative medicine has highlighted the benefits of olive as an integral part of therapeutic diet to promote healthy living. Among the thirty different phenolic compounds of olive known to date; oleocanthal, oleuropein, tyrosol and hydroxytyrosol are being increasingly investigat...

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Main Authors:	Khidhir Kamil, Jaya Kumar, Muhammad Dain Yazid, Ruszymah Hj Idrus
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/12663/ http://journalarticle.ukm.my/12663/ http://journalarticle.ukm.my/12663/1/24%20Khidhir%20Kamil.pdf

id	ukm-12663
recordtype	eprints
spelling	ukm-126632019-03-17T11:51:03Z http://journalarticle.ukm.my/12663/ Olive and its phenolic compound as the promising neuroprotective agent Khidhir Kamil, Jaya Kumar, Muhammad Dain Yazid, Ruszymah Hj Idrus, Recent progress in alternative medicine has highlighted the benefits of olive as an integral part of therapeutic diet to promote healthy living. Among the thirty different phenolic compounds of olive known to date; oleocanthal, oleuropein, tyrosol and hydroxytyrosol are being increasingly investigated for their potential in prevention and healing of several major forms of neurological dysfunctions and disorders. A considerable amount of literature suggests the neuroprotective effects of olive and its phenolic compounds are owing to their roles as anti-oxidant, anti-inflammatory and anti-apoptotic agents. At preclinical level, olive attenuated cognitive dysfunctions and the functional outcomes in spinal cord injury, delayed the progression of amyloid beta pathology, improved motor and mitochondrial dysfunctions in Parkinson’s disease, reversed diabetic-related neurological complications and also ameliorated cerebral pathologies in stroke. In this paper, we aim to review the neuroprotective role of olive and its phenolic derivatives in the following diseases or deficits of the nervous system that include cognitive dysfunction, neurodegenerative diseases, stroke, peripheral neuropathy and spinal cord injury. Penerbit Universiti Kebangsaan Malaysia 2018-11 Article NonPeerReviewed application/pdf en http://journalarticle.ukm.my/12663/1/24%20Khidhir%20Kamil.pdf Khidhir Kamil, and Jaya Kumar, and Muhammad Dain Yazid, and Ruszymah Hj Idrus, (2018) Olive and its phenolic compound as the promising neuroprotective agent. Sains Malaysiana, 47 (11). pp. 2811-2820. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol47num11_2018/contentsVol47num11_2018.htm
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Recent progress in alternative medicine has highlighted the benefits of olive as an integral part of therapeutic diet to promote healthy living. Among the thirty different phenolic compounds of olive known to date; oleocanthal, oleuropein, tyrosol and hydroxytyrosol are being increasingly investigated for their potential in prevention and healing of several major forms of neurological dysfunctions and disorders. A considerable amount of literature suggests the neuroprotective effects of olive and its phenolic compounds are owing to their roles as anti-oxidant, anti-inflammatory and anti-apoptotic agents. At preclinical level, olive attenuated cognitive dysfunctions and the functional outcomes in spinal cord injury, delayed the progression of amyloid beta pathology, improved motor and mitochondrial dysfunctions in Parkinson’s disease, reversed diabetic-related neurological complications and also ameliorated cerebral pathologies in stroke. In this paper, we aim to review the neuroprotective role of olive and its phenolic derivatives in the following diseases or deficits of the nervous system that include cognitive dysfunction, neurodegenerative diseases, stroke, peripheral neuropathy and spinal cord injury.
format	Article
author	Khidhir Kamil, Jaya Kumar, Muhammad Dain Yazid, Ruszymah Hj Idrus,
spellingShingle	Khidhir Kamil, Jaya Kumar, Muhammad Dain Yazid, Ruszymah Hj Idrus, Olive and its phenolic compound as the promising neuroprotective agent
author_facet	Khidhir Kamil, Jaya Kumar, Muhammad Dain Yazid, Ruszymah Hj Idrus,
author_sort	Khidhir Kamil,
title	Olive and its phenolic compound as the promising neuroprotective agent
title_short	Olive and its phenolic compound as the promising neuroprotective agent
title_full	Olive and its phenolic compound as the promising neuroprotective agent
title_fullStr	Olive and its phenolic compound as the promising neuroprotective agent
title_full_unstemmed	Olive and its phenolic compound as the promising neuroprotective agent
title_sort	olive and its phenolic compound as the promising neuroprotective agent
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2018
url	http://journalarticle.ukm.my/12663/ http://journalarticle.ukm.my/12663/ http://journalarticle.ukm.my/12663/1/24%20Khidhir%20Kamil.pdf
first_indexed	2023-09-18T20:03:07Z
last_indexed	2023-09-18T20:03:07Z
_version_	1777406980569169920

Olive and its phenolic compound as the promising neuroprotective agent

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