A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery

We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. Eighty-four ASA I or II patients, aged 18 to 65 years who underwent total abdominal hysterectomy were recruited into this prospective, double blind...

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Main Authors:	Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong, Omar S, Mahazir K
Format:	Article
Language:	English
Published:	Pusat Perubatan Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/12563/ http://journalarticle.ukm.my/12563/ http://journalarticle.ukm.my/12563/1/4.chen_jl_et_al.pdf

id	ukm-12563
recordtype	eprints
spelling	ukm-125632019-02-14T21:41:49Z http://journalarticle.ukm.my/12563/ A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong Omar S, Mahazir K, We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. Eighty-four ASA I or II patients, aged 18 to 65 years who underwent total abdominal hysterectomy were recruited into this prospective, double blind, randomised controlled study. They were randomised to receive either PCA oxycodone 0.7 mg per bolus or PCA morphine 1 mg per bolus for postoperative pain relief. At the end of surgery, all patients received IV morphine 0.1 mg/kg and skin incision was infiltrated with 20 mls of bupivacaine 0.25%. Post-operative pain scores, opioids consumptions, sedation scores and side effects were assessed upon arrival and at 30 minutes after arrival to recovery area, as well as at 6 hours and 24 hours after the operation in the ward. Patients’ overall satisfaction was also assessed 24 hours postoperatively.No significant differences were observed in terms of postoperative pain scores, opioids consumption, sedation scores, side effects as well as patient’s overall satisfaction between the PCA oxycodone and PCA morphine group. Oxycodone was comparable to morphine as PCA in terms of total opioid consumption, pain scores and satisfaction level for patients undergoing total abdominal hysterectomy and therefore may be an alternative to morphine in postoperative pain management as PCA. Pusat Perubatan Universiti Kebangsaan Malaysia 2018 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12563/1/4.chen_jl_et_al.pdf Chen JL, and Rufinah T, and Fadzlon Mohd Yatim, and Liu, Chian Yong and Omar S, and Mahazir K, (2018) A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery. Journal of Surgical Academia, 8 (2). pp. 17-22. ISSN 2231-7481 http://jsurgacad.com/toc
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. Eighty-four ASA I or II patients, aged 18 to 65 years who underwent total abdominal hysterectomy were recruited into this prospective, double blind, randomised controlled study. They were randomised to receive either PCA oxycodone 0.7 mg per bolus or PCA morphine 1 mg per bolus for postoperative pain relief. At the end of surgery, all patients received IV morphine 0.1 mg/kg and skin incision was infiltrated with 20 mls of bupivacaine 0.25%. Post-operative pain scores, opioids consumptions, sedation scores and side effects were assessed upon arrival and at 30 minutes after arrival to recovery area, as well as at 6 hours and 24 hours after the operation in the ward. Patients’ overall satisfaction was also assessed 24 hours postoperatively.No significant differences were observed in terms of postoperative pain scores, opioids consumption, sedation scores, side effects as well as patient’s overall satisfaction between the PCA oxycodone and PCA morphine group. Oxycodone was comparable to morphine as PCA in terms of total opioid consumption, pain scores and satisfaction level for patients undergoing total abdominal hysterectomy and therefore may be an alternative to morphine in postoperative pain management as PCA.
format	Article
author	Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong Omar S, Mahazir K,
spellingShingle	Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong Omar S, Mahazir K, A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
author_facet	Chen JL, Rufinah T, Fadzlon Mohd Yatim, Liu, Chian Yong Omar S, Mahazir K,
author_sort	Chen JL,
title	A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_short	A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_full	A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_fullStr	A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_full_unstemmed	A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
title_sort	comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
publisher	Pusat Perubatan Universiti Kebangsaan Malaysia
publishDate	2018
url	http://journalarticle.ukm.my/12563/ http://journalarticle.ukm.my/12563/ http://journalarticle.ukm.my/12563/1/4.chen_jl_et_al.pdf
first_indexed	2023-09-18T20:02:53Z
last_indexed	2023-09-18T20:02:53Z
_version_	1777406966342090752

A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery

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