Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia

The purpose of the present study was to assess quality of life (QOL) in n-AMD patients seen in a Malaysian public hospital and to further identify visual and demographic factors that may contribute to QOL scores of these patients. Patients with any form of n-AMD in at least one eye were recruited fr...

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Main Authors:	Rituparna Ghoshal, Sharanjeet Kaur, Norliza Mohamad Fadzil, Somnath Ghosh, NorFariza Ngah, Roslin Azni Abd Aziz
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/12515/ http://journalarticle.ukm.my/12515/ http://journalarticle.ukm.my/12515/1/21%20Sharanjeet%20Sharanjeet-Kaur.pdf

id	ukm-12515
recordtype	eprints
spelling	ukm-125152019-01-28T21:27:06Z http://journalarticle.ukm.my/12515/ Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia Rituparna Ghoshal, Sharanjeet Kaur, Norliza Mohamad Fadzil, Somnath Ghosh, NorFariza Ngah, Roslin Azni Abd Aziz, The purpose of the present study was to assess quality of life (QOL) in n-AMD patients seen in a Malaysian public hospital and to further identify visual and demographic factors that may contribute to QOL scores of these patients. Patients with any form of n-AMD in at least one eye were recruited from hospital’s ophthalmology department. Bahasa Malaysia version of National Eye Institute Visual function questionnaire-25 (NEI-VFQ-25) was administered to all participants. Demographics, visual functions (VF) including best corrected distance visual acuity (BCDVA), contrast sensitivity (CS), near visual acuity (NVA) and reading speed (RS) were recorded. Eighty-six patients (Malay=26, Indian=23, Chinese=37) aged 52 to 85 years, diagnosed with n-AMD were chosen to participate. Their mean NEI-VFQ composite score (NEI-VFQ CS) was 66.91 ± 13.07. However, no significant difference in NEI-VFQ CS between gender, races and between the two sub groups of n-AMD were observed (p>0.05). NEI-VFQ CS showed a significant association with RS (correlation coefficient (ρ) =0.627), NVA (ρ = -.660), BCDVA (ρ = -.586), CS (ρ =.0.515). A linear model showed that a combination of BCDVA, NVA, CS is accounted for a significant 38 % variability of NEI-VFQ CS (R2 =0.382, p<0.001). In conclusion, the QOL of Malaysian n-AMD patients were found to be low. Thus, the study results indicated the need of developing necessary management strategies to address this QOL issues in n-AMD patients in Malaysia. Furthermore, the present study suggested incorporating appropriate VF such as near acuity, contrast sensitivity, reading speed in clinical settings while assessing n-AMD patients as these VF explain the patient’s perception about the impact of this disease. Penerbit Universiti Kebangsaan Malaysia 2018-10 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12515/1/21%20Sharanjeet%20Sharanjeet-Kaur.pdf Rituparna Ghoshal, and Sharanjeet Kaur, and Norliza Mohamad Fadzil, and Somnath Ghosh, and NorFariza Ngah, and Roslin Azni Abd Aziz, (2018) Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia. Sains Malaysiana, 47 (10). pp. 2447-2454. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid47bil10_2018/KandunganJilid47Bil10_2018.htm
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	The purpose of the present study was to assess quality of life (QOL) in n-AMD patients seen in a Malaysian public hospital and to further identify visual and demographic factors that may contribute to QOL scores of these patients. Patients with any form of n-AMD in at least one eye were recruited from hospital’s ophthalmology department. Bahasa Malaysia version of National Eye Institute Visual function questionnaire-25 (NEI-VFQ-25) was administered to all participants. Demographics, visual functions (VF) including best corrected distance visual acuity (BCDVA), contrast sensitivity (CS), near visual acuity (NVA) and reading speed (RS) were recorded. Eighty-six patients (Malay=26, Indian=23, Chinese=37) aged 52 to 85 years, diagnosed with n-AMD were chosen to participate. Their mean NEI-VFQ composite score (NEI-VFQ CS) was 66.91 ± 13.07. However, no significant difference in NEI-VFQ CS between gender, races and between the two sub groups of n-AMD were observed (p>0.05). NEI-VFQ CS showed a significant association with RS (correlation coefficient (ρ) =0.627), NVA (ρ = -.660), BCDVA (ρ = -.586), CS (ρ =.0.515). A linear model showed that a combination of BCDVA, NVA, CS is accounted for a significant 38 % variability of NEI-VFQ CS (R2 =0.382, p<0.001). In conclusion, the QOL of Malaysian n-AMD patients were found to be low. Thus, the study results indicated the need of developing necessary management strategies to address this QOL issues in n-AMD patients in Malaysia. Furthermore, the present study suggested incorporating appropriate VF such as near acuity, contrast sensitivity, reading speed in clinical settings while assessing n-AMD patients as these VF explain the patient’s perception about the impact of this disease.
format	Article
author	Rituparna Ghoshal, Sharanjeet Kaur, Norliza Mohamad Fadzil, Somnath Ghosh, NorFariza Ngah, Roslin Azni Abd Aziz,
spellingShingle	Rituparna Ghoshal, Sharanjeet Kaur, Norliza Mohamad Fadzil, Somnath Ghosh, NorFariza Ngah, Roslin Azni Abd Aziz, Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia
author_facet	Rituparna Ghoshal, Sharanjeet Kaur, Norliza Mohamad Fadzil, Somnath Ghosh, NorFariza Ngah, Roslin Azni Abd Aziz,
author_sort	Rituparna Ghoshal,
title	Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia
title_short	Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia
title_full	Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia
title_fullStr	Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia
title_full_unstemmed	Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia
title_sort	quality of life in patients with neovascular age related macular degeneration (n-amd) seen in a public hospital of malaysia
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2018
url	http://journalarticle.ukm.my/12515/ http://journalarticle.ukm.my/12515/ http://journalarticle.ukm.my/12515/1/21%20Sharanjeet%20Sharanjeet-Kaur.pdf
first_indexed	2023-09-18T20:02:47Z
last_indexed	2023-09-18T20:02:47Z
_version_	1777406959779053568

Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia

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