Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters

This study was carried out to compare the effects of ethanolic extract of Cosmos caudatus (CCEE), Piper sarmentosum (PSEE) and Premna cordifolia (PCEE) on sperm parameters of male mice, Mus musculus. Twenty four sexually matured male mice were used in this study. The mice were grouped into 4 group...

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Main Authors:	Nabihah S., Dzulsuhaimi D., Nooraain H.
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/12295/ http://journalarticle.ukm.my/12295/ http://journalarticle.ukm.my/12295/1/46_01_02.pdf

id	ukm-12295
recordtype	eprints
spelling	ukm-122952018-11-16T11:21:17Z http://journalarticle.ukm.my/12295/ Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters Nabihah S., Dzulsuhaimi D., Nooraain H., This study was carried out to compare the effects of ethanolic extract of Cosmos caudatus (CCEE), Piper sarmentosum (PSEE) and Premna cordifolia (PCEE) on sperm parameters of male mice, Mus musculus. Twenty four sexually matured male mice were used in this study. The mice were grouped into 4 groups of 6 mice each. The first group was given 0.9% saline solution and served as a control whereas groups 2-4 were daily administered with 500 mg/kg body weight of CCEE, PSEE and PCEE respectively, orally for 30 days daily. The body weight was recorded prior to, and after the treatments. At the end of the experimental period, the mice were sacrificed by cervical dislocation. The testis and epidydimis were collected and weighed. Then, the sperm suspension was prepared and subjected to sperm analysis (sperm motility, count and morphology). Bodyweight and reproductive organ weight (testis and epididymis) were not significantly different between control and mice treated with CCEE, PSEE and PCEE. Sperm count was increased in all groups compared to control but not significantly different. Sperm motility of mice treated with PSEE significantly (p<0.05) increased compared to control. Meanwhile sperm motility was not affected by CCEE and PCEE. PCEE significantly (p<0.05) decreased the percentage of normal sperm morphology compared to control. CCEE and PSEE also reduced the percentage of normal sperm morphology but the values were not significantly different. This study proves that all of the three plants affect the sperm quality, thus further study is suggested. Penerbit Universiti Kebangsaan Malaysia 2017-03 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12295/1/46_01_02.pdf Nabihah S., and Dzulsuhaimi D., and Nooraain H., (2017) Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters. Malaysian Applied Biology, 46 (1). pp. 9-14. ISSN 0126-8643 http://www.mabjournal.com/index.php?option=com_content&view=article&id=623&catid=59:current-view&Itemid=56
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	This study was carried out to compare the effects of ethanolic extract of Cosmos caudatus (CCEE), Piper sarmentosum (PSEE) and Premna cordifolia (PCEE) on sperm parameters of male mice, Mus musculus. Twenty four sexually matured male mice were used in this study. The mice were grouped into 4 groups of 6 mice each. The first group was given 0.9% saline solution and served as a control whereas groups 2-4 were daily administered with 500 mg/kg body weight of CCEE, PSEE and PCEE respectively, orally for 30 days daily. The body weight was recorded prior to, and after the treatments. At the end of the experimental period, the mice were sacrificed by cervical dislocation. The testis and epidydimis were collected and weighed. Then, the sperm suspension was prepared and subjected to sperm analysis (sperm motility, count and morphology). Bodyweight and reproductive organ weight (testis and epididymis) were not significantly different between control and mice treated with CCEE, PSEE and PCEE. Sperm count was increased in all groups compared to control but not significantly different. Sperm motility of mice treated with PSEE significantly (p<0.05) increased compared to control. Meanwhile sperm motility was not affected by CCEE and PCEE. PCEE significantly (p<0.05) decreased the percentage of normal sperm morphology compared to control. CCEE and PSEE also reduced the percentage of normal sperm morphology but the values were not significantly different. This study proves that all of the three plants affect the sperm quality, thus further study is suggested.
format	Article
author	Nabihah S., Dzulsuhaimi D., Nooraain H.,
spellingShingle	Nabihah S., Dzulsuhaimi D., Nooraain H., Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters
author_facet	Nabihah S., Dzulsuhaimi D., Nooraain H.,
author_sort	Nabihah S.,
title	Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters
title_short	Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters
title_full	Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters
title_fullStr	Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters
title_full_unstemmed	Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters
title_sort	comparative effects of cosmos caudatus, piper sarmentosum and premna cordifolia ethanolic extracts on mice (mus musculus) sperm parameters
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2017
url	http://journalarticle.ukm.my/12295/ http://journalarticle.ukm.my/12295/ http://journalarticle.ukm.my/12295/1/46_01_02.pdf
first_indexed	2023-09-18T20:02:17Z
last_indexed	2023-09-18T20:02:17Z
_version_	1777406928262004736

Comparative effects of Cosmos caudatus, Piper sarmentosum and Premna cordifolia ethanolic extracts on mice (Mus musculus) sperm parameters

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