Phylogenetic analysis of Zika and dengue virus
Zika and Dengue virus are two viruses from of the family Flaviviridae, mosquito-borne Flavivirus, known as zoonosis disease because the viruses can transmitted to human by mosquito vector mainly Aedes aegypti. The outbreaks of Zika virus (ZIKV) was first confirmed case in the Brazil in May 2015. I...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Society of Applied Biology
2016
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| Online Access: | http://journalarticle.ukm.my/11829/ http://journalarticle.ukm.my/11829/ http://journalarticle.ukm.my/11829/1/45_02_24.pdf |
| Summary: | Zika and Dengue virus are two viruses from of the family Flaviviridae, mosquito-borne Flavivirus, known as zoonosis
disease because the viruses can transmitted to human by mosquito vector mainly Aedes aegypti. The outbreaks of Zika virus
(ZIKV) was first confirmed case in the Brazil in May 2015. It is currently one of the most important emerging viruses in the
world and has outbreaks and epidemics with severe clinical manifestations. Like Zika, Dengue virus has rapidly spread in all
areas of WHO in recent years and the source of outbreaks in areas of recent ZIKV introduction. This study aimed to determine
the evolutionary relationship among Zika and Dengue virus. The 220 complete genome (11kb) were downloaded from GenBank
database. Phylogenetic tree examined by constructed by Neighbor-Joining (NJ) method in the KIMURA-2 parameter model
and valued by bootstrap with 1000 replicates. The result showed that Zika virus has relationship between two strains of
DENV-4 where they were clustered together in phylogenetic tree. |
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