Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women

Daily food intake of women may affect their bone health by altering their bone mineral density (BMD) as the lack of certain nutrients may affect bone integrity whilst, BMD also can be a predictor of breast cancer. To date, many studies have been conducted to discuss on association of BMD and mammogr...

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Main Authors:	Norhayati Mohd Zain, Kanaga Kumari Chelliah, Vengkatha Priya Seriramulu, Shantini Arasaratnam, Poh, Bee Koon
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/11485/ http://journalarticle.ukm.my/11485/ http://journalarticle.ukm.my/11485/1/16760-56268-1-PB.pdf

id	ukm-11485
recordtype	eprints
spelling	ukm-114852018-03-16T00:59:17Z http://journalarticle.ukm.my/11485/ Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women Norhayati Mohd Zain, Kanaga Kumari Chelliah, Vengkatha Priya Seriramulu, Shantini Arasaratnam, Poh, Bee Koon Daily food intake of women may affect their bone health by altering their bone mineral density (BMD) as the lack of certain nutrients may affect bone integrity whilst, BMD also can be a predictor of breast cancer. To date, many studies have been conducted to discuss on association of BMD and mammographic breast density (MBD) and how both are related to breast cancer risks but no consideration has been made on dietary intake. Therefore, this study was designed to determine the association of dietary intake with BMD and other breast cancer risk factors. A cross-sectional study on 76 pre- and postmenopausal women above 40 years underwent mammogram screening and Dual Energy X-ray Absorptiometry (DEXA) was conducted in Hospital Kuala Lumpur (HKL) for the duration of 1 year. Purposive sampling method was used to choose the respondents. Women who are diagnosed with breast cancer and underwent cancer treatment were excluded from this study. DEXA unit (Hologic Discovery W, Hologic, Inc) were used to measure BMD at the femoral neck and lumbar spine in grams per centimetre squared (g/cm2) and they were classified into normal and abnormal group based on the T-scores. The subjects were asked about their daily dietary pattern for a duration of three days using Diet History Questionnaire (DHQ). The mean of selected characteristics were compared between groups. Additionally, binary logistic regression was used to determine the association between diet intake with BMD and other risk factors of breast cancer. The total number of pre- and postmenopausal women who consented to participate in this study are equal. The mean age was 47.1 years and 54.9 years for premenopausal and postmenopausal women respectively. The results indicate only menopausal age of the women was statistically significant (p < 0.05). A number of 17% premenopausal and 9% of postmenopausal women showed to have family history of breast cancer, however, it was not statistically significant (p = 0.12). There was no significant difference in daily energy intake of food in both groups (p = 0.22). None of the nutrients in daily food intake showed to be statistically significant. Menstrual status showed an association with BMD with p < 0.05 and the remaining risk factors did not show any association. Logistic regression revealed that only menstrual status had correlation with BMD in both groups. This study provided the dietary pattern and the effects on bone health. The association of other risk factors of breast cancer with BMD were also analysed and most of it showed a negative association. Penerbit Universiti Kebangsaan Malaysia 2017 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/11485/1/16760-56268-1-PB.pdf Norhayati Mohd Zain, and Kanaga Kumari Chelliah, and Vengkatha Priya Seriramulu, and Shantini Arasaratnam, and Poh, Bee Koon (2017) Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women. Jurnal Sains Kesihatan Malaysia, 15 (2(SI)). pp. 137-144. ISSN 1675-8161 http://ejournal.ukm.my/jskm/issue/view/894
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Daily food intake of women may affect their bone health by altering their bone mineral density (BMD) as the lack of certain nutrients may affect bone integrity whilst, BMD also can be a predictor of breast cancer. To date, many studies have been conducted to discuss on association of BMD and mammographic breast density (MBD) and how both are related to breast cancer risks but no consideration has been made on dietary intake. Therefore, this study was designed to determine the association of dietary intake with BMD and other breast cancer risk factors. A cross-sectional study on 76 pre- and postmenopausal women above 40 years underwent mammogram screening and Dual Energy X-ray Absorptiometry (DEXA) was conducted in Hospital Kuala Lumpur (HKL) for the duration of 1 year. Purposive sampling method was used to choose the respondents. Women who are diagnosed with breast cancer and underwent cancer treatment were excluded from this study. DEXA unit (Hologic Discovery W, Hologic, Inc) were used to measure BMD at the femoral neck and lumbar spine in grams per centimetre squared (g/cm2) and they were classified into normal and abnormal group based on the T-scores. The subjects were asked about their daily dietary pattern for a duration of three days using Diet History Questionnaire (DHQ). The mean of selected characteristics were compared between groups. Additionally, binary logistic regression was used to determine the association between diet intake with BMD and other risk factors of breast cancer. The total number of pre- and postmenopausal women who consented to participate in this study are equal. The mean age was 47.1 years and 54.9 years for premenopausal and postmenopausal women respectively. The results indicate only menopausal age of the women was statistically significant (p < 0.05). A number of 17% premenopausal and 9% of postmenopausal women showed to have family history of breast cancer, however, it was not statistically significant (p = 0.12). There was no significant difference in daily energy intake of food in both groups (p = 0.22). None of the nutrients in daily food intake showed to be statistically significant. Menstrual status showed an association with BMD with p < 0.05 and the remaining risk factors did not show any association. Logistic regression revealed that only menstrual status had correlation with BMD in both groups. This study provided the dietary pattern and the effects on bone health. The association of other risk factors of breast cancer with BMD were also analysed and most of it showed a negative association.
format	Article
author	Norhayati Mohd Zain, Kanaga Kumari Chelliah, Vengkatha Priya Seriramulu, Shantini Arasaratnam, Poh, Bee Koon
spellingShingle	Norhayati Mohd Zain, Kanaga Kumari Chelliah, Vengkatha Priya Seriramulu, Shantini Arasaratnam, Poh, Bee Koon Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women
author_facet	Norhayati Mohd Zain, Kanaga Kumari Chelliah, Vengkatha Priya Seriramulu, Shantini Arasaratnam, Poh, Bee Koon
author_sort	Norhayati Mohd Zain,
title	Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women
title_short	Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women
title_full	Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women
title_fullStr	Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women
title_full_unstemmed	Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women
title_sort	association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal malaysian women
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2017
url	http://journalarticle.ukm.my/11485/ http://journalarticle.ukm.my/11485/ http://journalarticle.ukm.my/11485/1/16760-56268-1-PB.pdf
first_indexed	2023-09-18T20:00:28Z
last_indexed	2023-09-18T20:00:28Z
_version_	1777406814038523904

Association of bone mineral density to dietary intake and predictors of breast cancer in premenopausal and postmenopausal Malaysian women

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