MGMT and SPOCK2 promoter methylation in diffuse large B-Cell lymphoma: a study in two tertiary health centres in the East Coast of Malaysia

MGMT and SPOCK2 promoter methylation in diffuse large B-Cell lymphoma: a study in two tertiary health centres in the East Coast of Malaysia

MGMT (O6-Methylguanine-DNA Methyltransferase) suppresses tumor development by removing alkyl adduct, while SPOCK2 (SPARC/Osteonectin CWCV and Kazal-like domains proteoglycan) abolishes the inhibition of membrane-type matrix metalloproteinases (MT-MMP) which leads to angiogenesis. Hence, MGMT methyla...

Full description

Bibliographic Details
Main Authors:	Norafiza Zainuddin, Lailatul Jalilah Mohd. Ridah, Aqilah Nabihah Omar, Norlelawati A. Talib, Naznin Muhammad, Faezahtul Arbaeyah Hussain
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/11475/ http://journalarticle.ukm.my/11475/ http://journalarticle.ukm.my/11475/1/16313-56210-2-PB.pdf

Similar Items

Methylation status of MGMT and SPOCK2 in diffuse large B-cell lymphoma
by: Zainuddin, Norafiza, et al.
Published: (2016)

Methylation-specific PCR Revealed Aberrant Promoter Gene Methylation of p16, MGMT and SPOCK2 in Diffuse Large B-cell Lymphoma
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2015)

Epigenetic methylation status of P16, MGMT and SPOCK2 in diffuse Large B cell lymphoma
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2016)

MGMT and SPOCK2 promoter methylation in diffuse large B-Cell lymphoma: a study in two tertiary health centres in the East Coast of Malaysia = Metilasi promoter MGMT dan SPOCK2 dalam diffuse large B-cell lymphoma: satu kajian yang dijalankan di dua pusat Kesihatan di Pantai Timur Malaysia
by: Zainuddin, Norafiza, et al.
Published: (2017)

p16 tumor suppressor gene methylation in diffuse large B cell lymphoma: a study of 88 cases at two hospitals in the East Coast of Malaysia
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2017)

Pyrosequencing-based quantitative identification of p16 methylation in diffuse large b-cell lymphoma at two centres in the east coast of malaysia
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2016)

Detection of p16INK4a (p16) methylation in diffuse large B-cell lymphoma using methylation-specific PCR
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2014)

Epigenetic silencing status of p16INK4a and MGMT promoter regions identified qualitatively in diffuse large B cell lymphoma
by: Mohd Ridah, L Jalilah, et al.
Published: (2015)

Qualitative detection of p16INK4a tumor suppressor gene methylation in diffuse large b-cell lymphoma using methylation-specific PCR
by: Mohd. Ridah, Lailatul Jalilah, et al.
Published: (2014)

Quantitative evaluation of p16INK4a promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma
by: Zainuddin, Norafiza, et al.
Published: (2011)

The MDM2 polymorphism SNP309 is associated with clinical characteristics and outcome in diffuse large B-cell lymphoma
by: Hedstrom, Gustav, et al.
Published: (2014)

Fetal down syndrome: determining the risk based on fetal-specific DNA methylation ratio
by: Zainuddin, Norafiza, et al.
Published: (2019)

Dr. Spock's baby basics
by: Needlman
Published: (2003)

Diffuse large B-cell lymphoma of the small intestine in a patient with refractory coeliac disease.
by: Ahmad Affandi, Khairunisa, et al.
Published: (2019)

TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype
by: Zainuddin, Norafiza, et al.
Published: (2008)

Dr. Spock's baby and child care
by: Spock
Published: (1998)

Methylation-sppecific PCR assay for quantification of DNA methylation of SPG20 gene in colorectal cancer
by: Mamat, Maizatul Akma, et al.
Published: (2017)

Primary cutaneous anaplastic large cell lymphoma with lung metastasis
by: Esa, Nor Kamaruzaman, et al.
Published: (2016)

Involvement of the P53 pathway and P161NK4A in the pathogenesis of b-cell lymphomas
by: Zainuddin, Norafiza
Published: (2011)

Molecular genetic analysis in B-cell Lymphomas : a focus on the p53 pathway and p16INK4a
by: Zainuddin, Norafiza
Published: (2010)

Hardfacing of duplex stainless steel using melting and diffusion processes
by: H, Lailatul, et al.
Published: (2017)

Microrna as a potential biomarker in the diagnosis and prognosis of Hodgkin’s lymphoma: a systematic review
by: Nik Izhar, Nik Nurdiyana, et al.
Published: (2019)

Anaplastic large cell lymphoma presenting as a soft tissue mass – A case report
by: Siti-Aishah M.A.,, et al.
Published: (2008)

Experimental study on flow around immersed objects
by: Lailatul Jalilah, Kaharudin
Published: (2014)

Oral cavity non-Hodgkin’s lymphoma: Clinicopathological aspects
by: Shweta N Kalyankar,
Published: (2015)

Multiple cavitating pulmonary nodules secondary to Hodgkin's lymphoma
by: Abdul Azih, Muhammad Naimuddin, et al.
Published: (2017)

Non-neoformans cryptococcemia in a patient with hodgkin’s lymphoma
by: Ding, Chuanhun, et al.
Published: (2018)

Modified surface of duplex stainless steel using tig torch and diffusion techniques
by: Maleque, Md. Abdul, et al.
Published: (2017)

Modified surface of duplex stainless steel using TIG torch melting and diffusion techniques
by: Maleque, Md. Abdul, et al.
Published: (2017)

Sacrospinous ligament fixation – a Malaysian’s tertiary centre experience
by: Norlelawati Ab Latip,, et al.
Published: (2017)

Bi-Atrial Primary Cardiac Lymphoma: a rare entity
by: Ngow, Harris Abdullah
Published: (2010)

Primary thyroid lymphoma: a rare malignancy in the head and neck
by: Mamat Nasir, Mohd Shaiful Nizam, et al.
Published: (2018)

Group- based quantitative structural activity relationship analysis of B-cell Lymphoma Extra Large (BCL-XL) inhibitors
by: Abdul Samat, Nadia Hanis, et al.
Published: (2014)

Arms diffusion the spread of military innovation in the international system
by: Zarzecki
Published: (2002)

Vapor-liquid equilibria in the systems methyl oleate + methanol & methyl oleate + water
by: Yong Ming, Lee
Published: (2010)

Correlation between severity of erosive reflux esophagitis and its manometric findings in a tertiary hospital at East Coast, Peninsular Malaysia
by: Mahno, Noor Ezmas, et al.
Published: (2015)

Methylation specific-high resolution melting analysis of DISC1
by: Abd. Rahim, Nour El Huda, et al.
Published: (2014)

The coast guardsman's manual
Published: (1991)

Information Diffusion in International Markets
by: Izquierdo, Alejandro, et al.
Published: (2014)

Acoustic absorbers and diffusers theory, design and application
by: Cox
Published: (2009)

Cannot write session to /tmp/vufind_sessions/sess_njl9ib2rqumhudq0kg362ev30b