Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts

Two species of plants, Andrographis paniculata and Euphorbia hirta were screened for antibacterial activities against three Gram positives and Gram negatives. The leaves from both plants were extracted by methanol extraction. The antibacterial activity was detected with spread plate well diffusion m...

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Main Authors:	Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian
Format:	Article
Language:	English
Published:	Penerbit UKM 2007
Online Access:	http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/1/jurnal76.pdf

id	ukm-1096
recordtype	eprints
spelling	ukm-10962016-12-14T06:28:48Z http://journalarticle.ukm.my/1096/ Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian Two species of plants, Andrographis paniculata and Euphorbia hirta were screened for antibacterial activities against three Gram positives and Gram negatives. The leaves from both plants were extracted by methanol extraction. The antibacterial activity was detected with spread plate well diffusion method. The extracts of both plants demonstrated inhibitory activity against both Gram negatives and positives bacteria. Staphylococcus aureus, Bacillus subtilis, Streptococcus epidemidis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) determination using micro dilution method showed that the MIC of A. paniculata for the tested bacteria were 1.56mg/ml (Staph. aureus), 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept. epidemidis), 1.56mg/ml (Escherichia coli), 12.50mg/ml (Klebsiella pneumoniae) and 3.13mg/ml (Pseudomonas aeruginosa)respectively. The MIC value for E. hirta was 6.25mg/ml (Staph. aureus) and 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept.Epidemidis), 3.13mg/ml (Psedomonas aeruginosa), 12.5mg/ml (Escherichia coli), and 6.25mg/ml (Klebsiella pneumoniae). Both plants represent a potential for pharmaceutical and agricultural applications and are worthy of further study. Penerbit UKM 2007 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/1096/1/jurnal76.pdf Ahmad Zorin Sahalan, and Nazahiyah Sulaiman, and Nihayah Mohammed, and Kaswandi Md. Ambia, and Hing, Hian Lian (2007) Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts. Jurnal Sains Kesihatan Malaysia, 5 (2). pp. 1-8. ISSN 1675-8161 http://www.fskb.ukm.my/fskbold
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Two species of plants, Andrographis paniculata and Euphorbia hirta were screened for antibacterial activities against three Gram positives and Gram negatives. The leaves from both plants were extracted by methanol extraction. The antibacterial activity was detected with spread plate well diffusion method. The extracts of both plants demonstrated inhibitory activity against both Gram negatives and positives bacteria. Staphylococcus aureus, Bacillus subtilis, Streptococcus epidemidis, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) determination using micro dilution method showed that the MIC of A. paniculata for the tested bacteria were 1.56mg/ml (Staph. aureus), 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept. epidemidis), 1.56mg/ml (Escherichia coli), 12.50mg/ml (Klebsiella pneumoniae) and 3.13mg/ml (Pseudomonas aeruginosa)respectively. The MIC value for E. hirta was 6.25mg/ml (Staph. aureus) and 3.13mg/ml (BAcillus subtilis), 3.13mg/ml (Strept.Epidemidis), 3.13mg/ml (Psedomonas aeruginosa), 12.5mg/ml (Escherichia coli), and 6.25mg/ml (Klebsiella pneumoniae). Both plants represent a potential for pharmaceutical and agricultural applications and are worthy of further study.
format	Article
author	Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian
spellingShingle	Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
author_facet	Ahmad Zorin Sahalan, Nazahiyah Sulaiman, Nihayah Mohammed, Kaswandi Md. Ambia, Hing, Hian Lian
author_sort	Ahmad Zorin Sahalan,
title	Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
title_short	Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
title_full	Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
title_fullStr	Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
title_full_unstemmed	Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
title_sort	antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts
publisher	Penerbit UKM
publishDate	2007
url	http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/ http://journalarticle.ukm.my/1096/1/jurnal76.pdf
first_indexed	2023-09-18T19:32:21Z
last_indexed	2023-09-18T19:32:21Z
_version_	1777405044763656192

Antibacterial activity of andrographis paniculata and euphorbia hirta methanol extracts

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