Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn

Nowadays, heavy usage of fungicide in agricultural industries has resulted in environmental pollution in additional to expose a significant risk to human health. Hence, there is a need to develop alternatives to replace synthetic fungicides. In this research, phytochemical test was carried out on...

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Main Authors:	Chu, Sue Yin, Harbant Singh, Muhammad Syarhabil Ahmad, Awang Soh Mamat
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2015
Online Access:	http://journalarticle.ukm.my/10348/ http://journalarticle.ukm.my/10348/ http://journalarticle.ukm.my/10348/1/44_1_14.pdf

id	ukm-10348
recordtype	eprints
spelling	ukm-103482017-04-21T09:50:26Z http://journalarticle.ukm.my/10348/ Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn Chu, Sue Yin Harbant Singh, Muhammad Syarhabil Ahmad, Awang Soh Mamat, Nowadays, heavy usage of fungicide in agricultural industries has resulted in environmental pollution in additional to expose a significant risk to human health. Hence, there is a need to develop alternatives to replace synthetic fungicides. In this research, phytochemical test was carried out on both fruits and leaves of Cerbera odollam Gaertn using standardized procedures to determine the antifungal compounds present in the ethanol extracts. Antifungal bioassay was performed through Kirby- Bauer disc diffusion method at various weight (0.5mg to 100mg) against fungi: Aspergillus niger, Fusarium oxysporum and Penicilium citrum. Fungi assay was assessed based on the minimum inhibitory amount of both ethanol extracts. The results of the research showed the presence of the active compounds such as alkaloid, cardiac glycoside, phenol, steroid, tannin and terpenoid in the extracts. Leaves extracts were found to have more phytoconstituents as compared to the fruits extracts. Besides, antifungal activity of leaves extract had moderate antifungal effects against Aspergillus niger (13.40mm inhibition zone) and Penicilium citrum (15.73mm inhibition zone). However, Fusarium oxysporum did not exhibit inhibition zone with this extract. Leaves extract showed best antifungal activity against Penicilium citrum, with the lowest dosage (<1mg) when compared to others. Meanwhile, fruits had showed weak antifungal activity (below 11.00mm inhibition zone) for all the tested fungi. The study on Cerbera odollam’s fruits and leaves extract indicated that they have an antifungal potential to be used as an alternative to synthetic fungicides. Investigation for its active biocompounds could be exploited further. Penerbit Universiti Kebangsaan Malaysia 2015-10 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/10348/1/44_1_14.pdf Chu, Sue Yin and Harbant Singh, and Muhammad Syarhabil Ahmad, and Awang Soh Mamat, (2015) Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn. Malaysian Applied Biology, 44 (3). pp. 75-79. ISSN 0126-8643 http://www.mabjournal.com/index.php?option=com_content&view=article&id=520&catid=59:current-view&Itemid=56
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Kebangasaan Malaysia
building	UKM Institutional Repository
collection	Online Access
language	English
description	Nowadays, heavy usage of fungicide in agricultural industries has resulted in environmental pollution in additional to expose a significant risk to human health. Hence, there is a need to develop alternatives to replace synthetic fungicides. In this research, phytochemical test was carried out on both fruits and leaves of Cerbera odollam Gaertn using standardized procedures to determine the antifungal compounds present in the ethanol extracts. Antifungal bioassay was performed through Kirby- Bauer disc diffusion method at various weight (0.5mg to 100mg) against fungi: Aspergillus niger, Fusarium oxysporum and Penicilium citrum. Fungi assay was assessed based on the minimum inhibitory amount of both ethanol extracts. The results of the research showed the presence of the active compounds such as alkaloid, cardiac glycoside, phenol, steroid, tannin and terpenoid in the extracts. Leaves extracts were found to have more phytoconstituents as compared to the fruits extracts. Besides, antifungal activity of leaves extract had moderate antifungal effects against Aspergillus niger (13.40mm inhibition zone) and Penicilium citrum (15.73mm inhibition zone). However, Fusarium oxysporum did not exhibit inhibition zone with this extract. Leaves extract showed best antifungal activity against Penicilium citrum, with the lowest dosage (<1mg) when compared to others. Meanwhile, fruits had showed weak antifungal activity (below 11.00mm inhibition zone) for all the tested fungi. The study on Cerbera odollam’s fruits and leaves extract indicated that they have an antifungal potential to be used as an alternative to synthetic fungicides. Investigation for its active biocompounds could be exploited further.
format	Article
author	Chu, Sue Yin Harbant Singh, Muhammad Syarhabil Ahmad, Awang Soh Mamat,
spellingShingle	Chu, Sue Yin Harbant Singh, Muhammad Syarhabil Ahmad, Awang Soh Mamat, Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn
author_facet	Chu, Sue Yin Harbant Singh, Muhammad Syarhabil Ahmad, Awang Soh Mamat,
author_sort	Chu, Sue Yin
title	Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn
title_short	Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn
title_full	Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn
title_fullStr	Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn
title_full_unstemmed	Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn
title_sort	phytochemical screening of antifungal biocompounds from fruits and leaves extract of cerbera odollam gaertn
publisher	Penerbit Universiti Kebangsaan Malaysia
publishDate	2015
url	http://journalarticle.ukm.my/10348/ http://journalarticle.ukm.my/10348/ http://journalarticle.ukm.my/10348/1/44_1_14.pdf
first_indexed	2023-09-18T19:57:09Z
last_indexed	2023-09-18T19:57:09Z
_version_	1777406605458931712

Phytochemical screening of antifungal biocompounds from fruits and leaves extract of Cerbera odollam Gaertn

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