The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin

The fungal species Candida albicans is an opportunistic pathogens which causes serious infections in humans, particularly in immunocompromised patients. Cinnamomum zeylanicum (cinnamon) or locally known as "kayu manis" has been reported to possess potent antifungal activity. Thus, this stu...

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Main Authors:	Nordin, Noor Hazarina, Ibrahim, Darah, Baharuddin, Siti Nurdijati
Format:	Article
Language:	English
Published:	Universiti Teknologi MARA, Pulau Pinang & Pusat Penerbitan Universiti (UPENA) 2008
Subjects:	Q Science (General) Antibacterial agents
Online Access:	http://ir.uitm.edu.my/id/eprint/4027/ http://ir.uitm.edu.my/id/eprint/4027/1/AJ_NOOR%20HAZARINA%20NORDIN%20ESTEEM%2008.pdf

id	uitm-4027
recordtype	eprints
spelling	uitm-40272017-03-09T03:19:41Z http://ir.uitm.edu.my/id/eprint/4027/ The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin Nordin, Noor Hazarina Ibrahim, Darah Baharuddin, Siti Nurdijati Q Science (General) Antibacterial agents The fungal species Candida albicans is an opportunistic pathogens which causes serious infections in humans, particularly in immunocompromised patients. Cinnamomum zeylanicum (cinnamon) or locally known as "kayu manis" has been reported to possess potent antifungal activity. Thus, this study evaluated the effects of C. zeylanicum chloroform extract on cell morphology ofC. albicans by observing the extract-treated yeast cells through scanning electron microscopy (SEM). Candida albicans cells morphology was observed to be lysed after 48 hours at various time intervals of exposure to the extract. The results indicated that the severity effect of cinnamon extract on the yeast cells was dependent on the time of exposure, and that the C. zeylanicum can inhibit filamentous growth of C. albicans cells. Electronic microscopy observations revealed that the sodium chloride (NaCl) crystals were probably primarily produced due to the extract-yeast reactions, which then contributing to the cells death. It is concluded that the cytoplasmic membrane is involved in the toxic action of the cinnamon crude extract. Universiti Teknologi MARA, Pulau Pinang & Pusat Penerbitan Universiti (UPENA) 2008 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/4027/1/AJ_NOOR%20HAZARINA%20NORDIN%20ESTEEM%2008.pdf Nordin, Noor Hazarina and Ibrahim, Darah and Baharuddin, Siti Nurdijati (2008) The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin. Esteem Academic Journal, 4 (2). pp. 31-38. ISSN 1675-7939
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Q Science (General) Antibacterial agents
spellingShingle	Q Science (General) Antibacterial agents Nordin, Noor Hazarina Ibrahim, Darah Baharuddin, Siti Nurdijati The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin
description	The fungal species Candida albicans is an opportunistic pathogens which causes serious infections in humans, particularly in immunocompromised patients. Cinnamomum zeylanicum (cinnamon) or locally known as "kayu manis" has been reported to possess potent antifungal activity. Thus, this study evaluated the effects of C. zeylanicum chloroform extract on cell morphology ofC. albicans by observing the extract-treated yeast cells through scanning electron microscopy (SEM). Candida albicans cells morphology was observed to be lysed after 48 hours at various time intervals of exposure to the extract. The results indicated that the severity effect of cinnamon extract on the yeast cells was dependent on the time of exposure, and that the C. zeylanicum can inhibit filamentous growth of C. albicans cells. Electronic microscopy observations revealed that the sodium chloride (NaCl) crystals were probably primarily produced due to the extract-yeast reactions, which then contributing to the cells death. It is concluded that the cytoplasmic membrane is involved in the toxic action of the cinnamon crude extract.
format	Article
author	Nordin, Noor Hazarina Ibrahim, Darah Baharuddin, Siti Nurdijati
author_facet	Nordin, Noor Hazarina Ibrahim, Darah Baharuddin, Siti Nurdijati
author_sort	Nordin, Noor Hazarina
title	The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin
title_short	The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin
title_full	The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin
title_fullStr	The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin
title_full_unstemmed	The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin
title_sort	structural modifications of candida albicans cells after treatment with cinnamomum zeylanicum blume crude extract / noor hazarina nordin, darah ibrahim and siti nurdijati baharuddin
publisher	Universiti Teknologi MARA, Pulau Pinang & Pusat Penerbitan Universiti (UPENA)
publishDate	2008
url	http://ir.uitm.edu.my/id/eprint/4027/ http://ir.uitm.edu.my/id/eprint/4027/1/AJ_NOOR%20HAZARINA%20NORDIN%20ESTEEM%2008.pdf
first_indexed	2023-09-18T22:46:52Z
last_indexed	2023-09-18T22:46:52Z
_version_	1777417283277160448

The structural modifications of Candida albicans cells after treatment with Cinnamomum zeylanicum blume crude extract / Noor Hazarina Nordin, Darah Ibrahim and Siti Nurdijati Baharuddin

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