Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman

Infertility is a biological inability of an individual to conceive and half of the cases are related to male infertility. Tocotrienols, a component of vitamin E, demonstrated the ability to improve the functions of male reproductive system. This study was performed to investigate the anti-infertilit...

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Main Author:	Sulaiman, Norzeila
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Specialties of internal medicine Examination. Diagnosis. Including radiography
Online Access:	http://ir.uitm.edu.my/id/eprint/27367/ http://ir.uitm.edu.my/id/eprint/27367/1/TD_NORZEILA%20SULAIMAN%20HS%2015_5.pdf

id	uitm-27367
recordtype	eprints
spelling	uitm-273672020-01-21T03:31:56Z http://ir.uitm.edu.my/id/eprint/27367/ Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman Sulaiman, Norzeila Specialties of internal medicine Examination. Diagnosis. Including radiography Infertility is a biological inability of an individual to conceive and half of the cases are related to male infertility. Tocotrienols, a component of vitamin E, demonstrated the ability to improve the functions of male reproductive system. This study was performed to investigate the anti-infertility effects of Tocotrienol Rich Fractions (TRF) from palm oil extract on male rat model. Fifteen male Wistar rats were randomly divided into 5 groups (n=3). Control negative group (F) was orally administered with distilled water (0.1 ml), control positive group (G) was orally administered with vitamin E-free corn oil (O.1ml) and treated groups were orally administered with three different concentrations of TRF, at a dose of 30 mg/kg (H), 60 mg/kg (I) and 90 mg/kg (J) respectively. After 7 days of acute treatment, the blood of the rats was collected using retro orbital sinus technique for biochemical investigation and hormonal analysis. The rats were sacrificed using cervical dislocation. The sperm were collected from cauda epididymis for analysis. TRF supplementation induced improvement in sperm morphology and motility compared to control negative group (F). In similar manner, TRF also provide positive effects to liver and renal function by reducing blood glucose and bilirubin level. Hormonal analysis demonstrated the ability of TRF to enhance LH production, which enhance spermatogenesis, thus helps in boosting fertility. This study suggested that TRF possesses the potential as anti-infertility agent and beneficial to the renal and liver function. 2015 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/27367/1/TD_NORZEILA%20SULAIMAN%20HS%2015_5.pdf Sulaiman, Norzeila (2015) Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman. Degree thesis, Universiti Teknologi MARA.
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Specialties of internal medicine Examination. Diagnosis. Including radiography
spellingShingle	Specialties of internal medicine Examination. Diagnosis. Including radiography Sulaiman, Norzeila Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman
description	Infertility is a biological inability of an individual to conceive and half of the cases are related to male infertility. Tocotrienols, a component of vitamin E, demonstrated the ability to improve the functions of male reproductive system. This study was performed to investigate the anti-infertility effects of Tocotrienol Rich Fractions (TRF) from palm oil extract on male rat model. Fifteen male Wistar rats were randomly divided into 5 groups (n=3). Control negative group (F) was orally administered with distilled water (0.1 ml), control positive group (G) was orally administered with vitamin E-free corn oil (O.1ml) and treated groups were orally administered with three different concentrations of TRF, at a dose of 30 mg/kg (H), 60 mg/kg (I) and 90 mg/kg (J) respectively. After 7 days of acute treatment, the blood of the rats was collected using retro orbital sinus technique for biochemical investigation and hormonal analysis. The rats were sacrificed using cervical dislocation. The sperm were collected from cauda epididymis for analysis. TRF supplementation induced improvement in sperm morphology and motility compared to control negative group (F). In similar manner, TRF also provide positive effects to liver and renal function by reducing blood glucose and bilirubin level. Hormonal analysis demonstrated the ability of TRF to enhance LH production, which enhance spermatogenesis, thus helps in boosting fertility. This study suggested that TRF possesses the potential as anti-infertility agent and beneficial to the renal and liver function.
format	Thesis
author	Sulaiman, Norzeila
author_facet	Sulaiman, Norzeila
author_sort	Sulaiman, Norzeila
title	Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman
title_short	Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman
title_full	Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman
title_fullStr	Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman
title_full_unstemmed	Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman
title_sort	effect of paternal supplementation of palm oil (tocotrienol rich fraction) on male fertility / norzeila sulaiman
publishDate	2015
url	http://ir.uitm.edu.my/id/eprint/27367/ http://ir.uitm.edu.my/id/eprint/27367/1/TD_NORZEILA%20SULAIMAN%20HS%2015_5.pdf
first_indexed	2023-09-18T23:18:20Z
last_indexed	2023-09-18T23:18:20Z
_version_	1777419262987599872

Effect of paternal supplementation of palm oil (Tocotrienol Rich Fraction) on male fertility / Norzeila Sulaiman

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