Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin

Study had been done on the synthesis of Schiff base ligand. The condensation between amine and carbonyl group produced an azomethine group (C=N) or also known as Schiff base ligand. In this study, the condensation between salicydehyde and propane-1,3-diamine lead to the formation of 2,2'-((1E,1...

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Main Author: Jamaludin, Nur Mira Nabilah
Format: Student Project
Language:English
Published: Faculty of Applied Sciences 2016
Subjects:
Online Access:http://ir.uitm.edu.my/id/eprint/24534/
http://ir.uitm.edu.my/id/eprint/24534/1/PPb_NUR%20MIRA%20NABILAH%20JAMALUDIN%20AS%20N%2016_5.pdf
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spelling uitm-245342019-07-19T00:34:03Z http://ir.uitm.edu.my/id/eprint/24534/ Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin Jamaludin, Nur Mira Nabilah QD Chemistry Schiff bases Study had been done on the synthesis of Schiff base ligand. The condensation between amine and carbonyl group produced an azomethine group (C=N) or also known as Schiff base ligand. In this study, the condensation between salicydehyde and propane-1,3-diamine lead to the formation of 2,2'-((1E,1'E)-(propane-1,3-diylbis(azanylylidene))bis(methanylylidene))diphenol (HL). The ligand undergo further complexation with metal centre lead to the formation of metal complex. In this study, nickel(II) nitrate was used as the metal salt producing nickel complex (CL). The ligand and its complex were characterized by elemental analysis (CHNS), Infrared Radiation (IR) spectroscopy analysis, detections of melting point, molar conductivity and UV-Vis spectroscopy analysis. The result obtained shows that the measurement ligand coordinate to the metal centre through azomethine nitrogen (N,N) producing a bidentate ligand. The ligand and the metal complex were tested against gram positive and gram negative bacteria. The activity data shows that the metal complex are more potent antimicrobial compared to the parent Schiff base ligand of the metal complex. Faculty of Applied Sciences 2016 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/24534/1/PPb_NUR%20MIRA%20NABILAH%20JAMALUDIN%20AS%20N%2016_5.pdf Jamaludin, Nur Mira Nabilah (2016) Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin. [Student Project] (Submitted)
repository_type Digital Repository
institution_category Local University
institution Universiti Teknologi MARA
building UiTM Institutional Repository
collection Online Access
language English
topic QD Chemistry
Schiff bases
spellingShingle QD Chemistry
Schiff bases
Jamaludin, Nur Mira Nabilah
Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin
description Study had been done on the synthesis of Schiff base ligand. The condensation between amine and carbonyl group produced an azomethine group (C=N) or also known as Schiff base ligand. In this study, the condensation between salicydehyde and propane-1,3-diamine lead to the formation of 2,2'-((1E,1'E)-(propane-1,3-diylbis(azanylylidene))bis(methanylylidene))diphenol (HL). The ligand undergo further complexation with metal centre lead to the formation of metal complex. In this study, nickel(II) nitrate was used as the metal salt producing nickel complex (CL). The ligand and its complex were characterized by elemental analysis (CHNS), Infrared Radiation (IR) spectroscopy analysis, detections of melting point, molar conductivity and UV-Vis spectroscopy analysis. The result obtained shows that the measurement ligand coordinate to the metal centre through azomethine nitrogen (N,N) producing a bidentate ligand. The ligand and the metal complex were tested against gram positive and gram negative bacteria. The activity data shows that the metal complex are more potent antimicrobial compared to the parent Schiff base ligand of the metal complex.
format Student Project
author Jamaludin, Nur Mira Nabilah
author_facet Jamaludin, Nur Mira Nabilah
author_sort Jamaludin, Nur Mira Nabilah
title Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin
title_short Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin
title_full Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin
title_fullStr Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin
title_full_unstemmed Synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / Nur Mira Nabilah Jamaludin
title_sort synthesis, characterization and antimicrobial screening of schiff base ligand and its metal complex / nur mira nabilah jamaludin
publisher Faculty of Applied Sciences
publishDate 2016
url http://ir.uitm.edu.my/id/eprint/24534/
http://ir.uitm.edu.my/id/eprint/24534/1/PPb_NUR%20MIRA%20NABILAH%20JAMALUDIN%20AS%20N%2016_5.pdf
first_indexed 2023-09-18T23:12:48Z
last_indexed 2023-09-18T23:12:48Z
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