Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak

The phytochemical screening of Goniothalamus species has been studied. Ground barks of Goniothalamus species were extracted at room temperature with hexane, chloroform and methanol solvent successively by using cool extraction method. Then, the extract was evaporated using rotary evaporator to produ...

Full description

Bibliographic Details
Main Author:	Abd Razak, Nur Zarifah
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences 2016
Subjects:	QD Chemistry Chemical elements Extraction (Chemistry) Botanical chemistry. Phytochemicals
Online Access:	http://ir.uitm.edu.my/id/eprint/24085/ http://ir.uitm.edu.my/id/eprint/24085/1/PPb_NUR%20ZARIFAH%20ABD%20RAZAK%20AS%20N%2016_5.pdf

id	uitm-24085
recordtype	eprints
spelling	uitm-240852019-05-08T01:00:24Z http://ir.uitm.edu.my/id/eprint/24085/ Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak Abd Razak, Nur Zarifah QD Chemistry Chemical elements Extraction (Chemistry) Botanical chemistry. Phytochemicals The phytochemical screening of Goniothalamus species has been studied. Ground barks of Goniothalamus species were extracted at room temperature with hexane, chloroform and methanol solvent successively by using cool extraction method. Then, the extract was evaporated using rotary evaporator to produce crude extract. The aim of this study is to extract the plant and to perform the phytochemical screening on the crude extract, to determine the TLC profile of crudes extract using thin layer chromatography (TLC) method and to screen the antibacterial activities of crude and fractionation of plant. Antibacterial assays were tested using disc diffusion method. Phytochemical screening of compounds such as alkaloid, flavonoid, phenol, tannin and terpenoid were detected using different tests on the methanol extracts. Suitable combination of solvent system was chosen to determine the TLC profile using thin layer chromatography method that were tested on the chloroform and methanol crude. For the antibacterial activity, the bacteria that employed for gram positive bacteria were Bacillus subtilis and Staphylococcus aureus while for gram negative bacteria were Escherichia coli and Salmonella sp. Four bacteria strains against the three extracts were determined using the disc diffusion method. The highest antibacterial activity observed was methanol extract against E. coli with inhibited diameter 20 mm while the lowest antibacterial activity observed was hexane extract against S. aureus 7 mm respectively. Faculty of Applied Sciences 2016 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/24085/1/PPb_NUR%20ZARIFAH%20ABD%20RAZAK%20AS%20N%2016_5.pdf Abd Razak, Nur Zarifah (2016) Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak. [Student Project] (Submitted)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry Chemical elements Extraction (Chemistry) Botanical chemistry. Phytochemicals
spellingShingle	QD Chemistry Chemical elements Extraction (Chemistry) Botanical chemistry. Phytochemicals Abd Razak, Nur Zarifah Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak
description	The phytochemical screening of Goniothalamus species has been studied. Ground barks of Goniothalamus species were extracted at room temperature with hexane, chloroform and methanol solvent successively by using cool extraction method. Then, the extract was evaporated using rotary evaporator to produce crude extract. The aim of this study is to extract the plant and to perform the phytochemical screening on the crude extract, to determine the TLC profile of crudes extract using thin layer chromatography (TLC) method and to screen the antibacterial activities of crude and fractionation of plant. Antibacterial assays were tested using disc diffusion method. Phytochemical screening of compounds such as alkaloid, flavonoid, phenol, tannin and terpenoid were detected using different tests on the methanol extracts. Suitable combination of solvent system was chosen to determine the TLC profile using thin layer chromatography method that were tested on the chloroform and methanol crude. For the antibacterial activity, the bacteria that employed for gram positive bacteria were Bacillus subtilis and Staphylococcus aureus while for gram negative bacteria were Escherichia coli and Salmonella sp. Four bacteria strains against the three extracts were determined using the disc diffusion method. The highest antibacterial activity observed was methanol extract against E. coli with inhibited diameter 20 mm while the lowest antibacterial activity observed was hexane extract against S. aureus 7 mm respectively.
format	Student Project
author	Abd Razak, Nur Zarifah
author_facet	Abd Razak, Nur Zarifah
author_sort	Abd Razak, Nur Zarifah
title	Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak
title_short	Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak
title_full	Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak
title_fullStr	Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak
title_full_unstemmed	Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak
title_sort	phytochemical screening and antibacterial activity of goniothalamus species / nur zarifah abd razak
publisher	Faculty of Applied Sciences
publishDate	2016
url	http://ir.uitm.edu.my/id/eprint/24085/ http://ir.uitm.edu.my/id/eprint/24085/1/PPb_NUR%20ZARIFAH%20ABD%20RAZAK%20AS%20N%2016_5.pdf
first_indexed	2023-09-18T23:11:50Z
last_indexed	2023-09-18T23:11:50Z
_version_	1777418854197100544

Phytochemical screening and antibacterial activity of goniothalamus species / Nur Zarifah Abd Razak

Similar Items