Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam

Leea indica is a medicinal plant that has been widely used as traditional remedy in curing many diseases. This study focused on isolation and preliminary identification of active compounds from the three different stem extracts of L. indica that have anti-oxidant and anti-microbial properties. Th...

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Main Author:	Mohd Azam, Naila Nabihah
Format:	Student Project
Language:	English
Published:	Faculty Of Applied Sciences 2016
Subjects:	Physical and theoretical chemistry
Online Access:	http://ir.uitm.edu.my/id/eprint/23125/ http://ir.uitm.edu.my/id/eprint/23125/1/PPb_NAILA%20NABIHAH%20MOHD%20AZAM%20AS%20C%2016_5.PDF

id	uitm-23125
recordtype	eprints
spelling	uitm-231252019-02-25T07:39:25Z http://ir.uitm.edu.my/id/eprint/23125/ Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam Mohd Azam, Naila Nabihah Physical and theoretical chemistry Leea indica is a medicinal plant that has been widely used as traditional remedy in curing many diseases. This study focused on isolation and preliminary identification of active compounds from the three different stem extracts of L. indica that have anti-oxidant and anti-microbial properties. The isolated active compounds from dichloromethane (DCM) extract at Rf 0.17 and Rf 0.25 was identified as 9-0ctadecane and Aromatic compound after subjected to FTIR, NMR and GC-MS. In DPPH radical scavenging activity analysis, all of the three extracts exhibit anti-oxidant properties where only methanol (MeOH) extract is the most anti-oxidative. The IC50 of MeOH extract is 1.14 ug/ml, which exceed the IC50 of Ascorbic acid (standard) which only 1.12 ug/ml. The stem extracts of this plant exhibit both anti-oxidant and anti-microbial properties. MeOH stem extract showed the strongest anti-oxidant activity due to presence of phenolic compound in the extract which known as strong radical scavengers. The stem of L. indica was proved containing active compounds that have anti-oxidant and anti-microbial properties. Faculty Of Applied Sciences 2016 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/23125/1/PPb_NAILA%20NABIHAH%20MOHD%20AZAM%20AS%20C%2016_5.PDF Mohd Azam, Naila Nabihah (2016) Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Physical and theoretical chemistry
spellingShingle	Physical and theoretical chemistry Mohd Azam, Naila Nabihah Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam
description	Leea indica is a medicinal plant that has been widely used as traditional remedy in curing many diseases. This study focused on isolation and preliminary identification of active compounds from the three different stem extracts of L. indica that have anti-oxidant and anti-microbial properties. The isolated active compounds from dichloromethane (DCM) extract at Rf 0.17 and Rf 0.25 was identified as 9-0ctadecane and Aromatic compound after subjected to FTIR, NMR and GC-MS. In DPPH radical scavenging activity analysis, all of the three extracts exhibit anti-oxidant properties where only methanol (MeOH) extract is the most anti-oxidative. The IC50 of MeOH extract is 1.14 ug/ml, which exceed the IC50 of Ascorbic acid (standard) which only 1.12 ug/ml. The stem extracts of this plant exhibit both anti-oxidant and anti-microbial properties. MeOH stem extract showed the strongest anti-oxidant activity due to presence of phenolic compound in the extract which known as strong radical scavengers. The stem of L. indica was proved containing active compounds that have anti-oxidant and anti-microbial properties.
format	Student Project
author	Mohd Azam, Naila Nabihah
author_facet	Mohd Azam, Naila Nabihah
author_sort	Mohd Azam, Naila Nabihah
title	Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam
title_short	Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam
title_full	Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam
title_fullStr	Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam
title_full_unstemmed	Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam
title_sort	isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / naila nabihah mohd azam
publisher	Faculty Of Applied Sciences
publishDate	2016
url	http://ir.uitm.edu.my/id/eprint/23125/ http://ir.uitm.edu.my/id/eprint/23125/1/PPb_NAILA%20NABIHAH%20MOHD%20AZAM%20AS%20C%2016_5.PDF
first_indexed	2023-09-18T23:10:07Z
last_indexed	2023-09-18T23:10:07Z
_version_	1777418745570918400

Isolation and preliminary identification of active compounds from the stem of leea indica (memali) using chromatographic technique / Naila Nabihah Mohd Azam

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