Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin

This study was conducted to evaluate aqueous and ethanolic extracts of Aloe barbadensis, Centella asiatica, Psidium guajava leaves, Pandanus amaryllifolius, Lantana camara and Andrographis paniculata for wound healing activities. Wound healing activities of all selected plants were determined using...

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Main Author:	Taisin, Prisallester Trennah
Format:	Student Project
Language:	English
Published:	Faculty of Applied Sciences 2009
Subjects:	Extraction (Chemistry)
Online Access:	http://ir.uitm.edu.my/id/eprint/23046/ http://ir.uitm.edu.my/id/eprint/23046/1/PPb_PRISALLESTER%20TRENNAH%20TAISIN%20AS%2009_5.pdf

id	uitm-23046
recordtype	eprints
spelling	uitm-230462019-02-27T09:08:24Z http://ir.uitm.edu.my/id/eprint/23046/ Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin Taisin, Prisallester Trennah Extraction (Chemistry) This study was conducted to evaluate aqueous and ethanolic extracts of Aloe barbadensis, Centella asiatica, Psidium guajava leaves, Pandanus amaryllifolius, Lantana camara and Andrographis paniculata for wound healing activities. Wound healing activities of all selected plants were determined using the excision wound model. The wound healing parameters that were evaluated in this study are wound contraction and epithelialization time. Anti-inflammatory, anti-oxidant and antimicrobial properties are responsible in wound healing. All selected plants possess these properties, thus they have potential in wound healing. From this study, it is found that aqueous extract of Aloe barbadensis is the most effective in wound healing with 92.1%) (17 days epithelialzation time) of wound contraction followed by ethanolic extract of Aloe barbadensis, aqueous extract of Andrographis paniculata, ethanolic extract of Andrographis paniculata, aqueous extract of Centella asiatica, ethanolic extract of Centella asiatica, aqueous extract of Lantana camara, ethanolic extract of Lantana camara, ethanolic extract of Pandanus amaryllifolius, aqueous extract of Psidium guajava leaves and lastly ethanolic extract of Psidium guajava leaves with percentage of wound contraction 89.5% (17 days epithelialzation time), 84.0% (18 days epithelialzation time), 80.9%) (18 days epithelialzation time) , 80.6%) (18 days epithelialzation time), 77.7% (19 days epithelialzation time), 76.5%) (19 days epithelialzation time), 74.3% (20 days epithelialzation time), 71.9% (20 days epithelialzation time), 69.3% (21 days epithelialzation time), 64.2% (22 days epithelialzation time) and 58.3% (22 days epithelialzation time) respectively. This gives a clear picture that aqueous extracts of all selected plants are better in wound healing compared to ethanolic extracts. Faculty of Applied Sciences 2009 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/23046/1/PPb_PRISALLESTER%20TRENNAH%20TAISIN%20AS%2009_5.pdf Taisin, Prisallester Trennah (2009) Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Extraction (Chemistry)
spellingShingle	Extraction (Chemistry) Taisin, Prisallester Trennah Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin
description	This study was conducted to evaluate aqueous and ethanolic extracts of Aloe barbadensis, Centella asiatica, Psidium guajava leaves, Pandanus amaryllifolius, Lantana camara and Andrographis paniculata for wound healing activities. Wound healing activities of all selected plants were determined using the excision wound model. The wound healing parameters that were evaluated in this study are wound contraction and epithelialization time. Anti-inflammatory, anti-oxidant and antimicrobial properties are responsible in wound healing. All selected plants possess these properties, thus they have potential in wound healing. From this study, it is found that aqueous extract of Aloe barbadensis is the most effective in wound healing with 92.1%) (17 days epithelialzation time) of wound contraction followed by ethanolic extract of Aloe barbadensis, aqueous extract of Andrographis paniculata, ethanolic extract of Andrographis paniculata, aqueous extract of Centella asiatica, ethanolic extract of Centella asiatica, aqueous extract of Lantana camara, ethanolic extract of Lantana camara, ethanolic extract of Pandanus amaryllifolius, aqueous extract of Psidium guajava leaves and lastly ethanolic extract of Psidium guajava leaves with percentage of wound contraction 89.5% (17 days epithelialzation time), 84.0% (18 days epithelialzation time), 80.9%) (18 days epithelialzation time) , 80.6%) (18 days epithelialzation time), 77.7% (19 days epithelialzation time), 76.5%) (19 days epithelialzation time), 74.3% (20 days epithelialzation time), 71.9% (20 days epithelialzation time), 69.3% (21 days epithelialzation time), 64.2% (22 days epithelialzation time) and 58.3% (22 days epithelialzation time) respectively. This gives a clear picture that aqueous extracts of all selected plants are better in wound healing compared to ethanolic extracts.
format	Student Project
author	Taisin, Prisallester Trennah
author_facet	Taisin, Prisallester Trennah
author_sort	Taisin, Prisallester Trennah
title	Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin
title_short	Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin
title_full	Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin
title_fullStr	Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin
title_full_unstemmed	Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin
title_sort	evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / prisallester trennah taisin
publisher	Faculty of Applied Sciences
publishDate	2009
url	http://ir.uitm.edu.my/id/eprint/23046/ http://ir.uitm.edu.my/id/eprint/23046/1/PPb_PRISALLESTER%20TRENNAH%20TAISIN%20AS%2009_5.pdf
first_indexed	2023-09-18T23:09:58Z
last_indexed	2023-09-18T23:09:58Z
_version_	1777418736415801344

Evaluation of wound healing activity of ethanolic and aqueous extracts of plants on rats / Prisallester Trennah Taisin

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