Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman

Strobilanthes crispus also known as "Pokok pecah kaca" is a local herbs plant belong to family Acanthaceae. Synthetic drug had given the drawback and herbs plant can replaced the drug in term of medication. The leaves were selected because of its variety benefits in traditional folk med...

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Main Author:	Muhamad Kamarazzaman, Nurfarahin
Format:	Student Project
Language:	English
Published:	Faculty Of Applied Sciences 2017
Subjects:	Physical plant physiology Botanical chemistry. Phytochemicals
Online Access:	http://ir.uitm.edu.my/id/eprint/22910/ http://ir.uitm.edu.my/id/eprint/22910/1/PPb_NURFARAHIN%20MUHAMAD%20KAMARAZZAMAN%20AS%20C%2017_5.PDF

id	uitm-22910
recordtype	eprints
spelling	uitm-229102019-01-23T00:44:27Z http://ir.uitm.edu.my/id/eprint/22910/ Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman Muhamad Kamarazzaman, Nurfarahin Physical plant physiology Botanical chemistry. Phytochemicals Strobilanthes crispus also known as "Pokok pecah kaca" is a local herbs plant belong to family Acanthaceae. Synthetic drug had given the drawback and herbs plant can replaced the drug in term of medication. The leaves were selected because of its variety benefits in traditional folk medicine to treat diabetes and anticancer treatment This study was done to determine the antimicrobial activity against Gram Positive bacteria which were Staphylococcus aureus and Bacillus subtilis, and Gram Negative bacteria which were Klebsiella pneumoniae and Pseudomonas aeruginosa. This study also wants to investigate the phytochemical compound that present in leaves of S.crispus. The minimal inhibitory concentration (MIC) also been carried out. The antimicrobial activity of S.crispus leaves extract against selected bacteria was tested at different concentrations using disc diffusion method. Identification of the phytochemical compound was determined through phytochemical screening. In methanol extract, the highest antimicrobial activities were at 400mg/ml concentration against P.aeruginosa with 12.67 mm of inhibition zone while, the lowest was against K.pneumoniae with 8.66 mm of inhibition zone at 200mg/ml concentration. The leaves extract of S.crispus in hexane solvent give no inhibition zone at all concentration in this study. The phytochemical screening showed positive result for the presence of flavonoid and saponins in both leaves extract. The MIC for methanol extract was determined at 25mglml against P.aeruginosa. In conclusion, S.crispus leaves extract showed the best potential to inhibit P.aeruginosa at 400mg/ml concentration. Further investigation should be conducted on other species of bacteria using other part of this plant. Faculty Of Applied Sciences 2017 Student Project NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/22910/1/PPb_NURFARAHIN%20MUHAMAD%20KAMARAZZAMAN%20AS%20C%2017_5.PDF Muhamad Kamarazzaman, Nurfarahin (2017) Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman. [Student Project] (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Physical plant physiology Botanical chemistry. Phytochemicals
spellingShingle	Physical plant physiology Botanical chemistry. Phytochemicals Muhamad Kamarazzaman, Nurfarahin Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
description	Strobilanthes crispus also known as "Pokok pecah kaca" is a local herbs plant belong to family Acanthaceae. Synthetic drug had given the drawback and herbs plant can replaced the drug in term of medication. The leaves were selected because of its variety benefits in traditional folk medicine to treat diabetes and anticancer treatment This study was done to determine the antimicrobial activity against Gram Positive bacteria which were Staphylococcus aureus and Bacillus subtilis, and Gram Negative bacteria which were Klebsiella pneumoniae and Pseudomonas aeruginosa. This study also wants to investigate the phytochemical compound that present in leaves of S.crispus. The minimal inhibitory concentration (MIC) also been carried out. The antimicrobial activity of S.crispus leaves extract against selected bacteria was tested at different concentrations using disc diffusion method. Identification of the phytochemical compound was determined through phytochemical screening. In methanol extract, the highest antimicrobial activities were at 400mg/ml concentration against P.aeruginosa with 12.67 mm of inhibition zone while, the lowest was against K.pneumoniae with 8.66 mm of inhibition zone at 200mg/ml concentration. The leaves extract of S.crispus in hexane solvent give no inhibition zone at all concentration in this study. The phytochemical screening showed positive result for the presence of flavonoid and saponins in both leaves extract. The MIC for methanol extract was determined at 25mglml against P.aeruginosa. In conclusion, S.crispus leaves extract showed the best potential to inhibit P.aeruginosa at 400mg/ml concentration. Further investigation should be conducted on other species of bacteria using other part of this plant.
format	Student Project
author	Muhamad Kamarazzaman, Nurfarahin
author_facet	Muhamad Kamarazzaman, Nurfarahin
author_sort	Muhamad Kamarazzaman, Nurfarahin
title	Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
title_short	Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
title_full	Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
title_fullStr	Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
title_full_unstemmed	Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman
title_sort	phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / nurfarahin muhamad kamarazzaman
publisher	Faculty Of Applied Sciences
publishDate	2017
url	http://ir.uitm.edu.my/id/eprint/22910/ http://ir.uitm.edu.my/id/eprint/22910/1/PPb_NURFARAHIN%20MUHAMAD%20KAMARAZZAMAN%20AS%20C%2017_5.PDF
first_indexed	2023-09-18T23:09:40Z
last_indexed	2023-09-18T23:09:40Z
_version_	1777418717833986048

Phytochemical screening and antimicrobial activities of strobilanthes crispus against selected bacteria / Nurfarahin Muhamad Kamarazzaman

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