The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman

Purpose: The aim of this thesis was to determine the diagnostic accuracy as well as the sensitivity of CT scan and MRI in detecting hepatocellular carcinoma HCC). Methodology: This is a retrospective study to identify the sensitivity and specificity of CT scan and MRI in detecting HCC. The study wa...

Full description

Bibliographic Details
Main Author:	Osman, Nurain
Format:	Thesis
Language:	English
Published:	2015
Subjects:	Medical technology Cancer Diseases of the lungs Radiography Radiographic magnification
Online Access:	http://ir.uitm.edu.my/id/eprint/22284/ http://ir.uitm.edu.my/id/eprint/22284/1/TD_NURAIN%20OSMAN%20HS%20B%2015_5.pdf

id	uitm-22284
recordtype	eprints
spelling	uitm-222842018-12-26T06:21:58Z http://ir.uitm.edu.my/id/eprint/22284/ The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman Osman, Nurain Medical technology Cancer Diseases of the lungs Radiography Radiographic magnification Purpose: The aim of this thesis was to determine the diagnostic accuracy as well as the sensitivity of CT scan and MRI in detecting hepatocellular carcinoma HCC). Methodology: This is a retrospective study to identify the sensitivity and specificity of CT scan and MRI in detecting HCC. The study was done at Diagnostic and Radiology Department, Selayang Hospital. The time frame for the sample data collection was taken from January 2013 until March 2015. 74 samples were selected based on the inclusion criteria of the study. The patient data selections were strictly the patients who underwent for both CT scan and MRI for detection of HCC. The reference of standard that was used to confirm the presence of the HCC included other interventional findings such as percutaneous biopsy, surgical resection and liver transplant. Result: The results were used in Bayers’ theorem to calculate the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of CT scan and MRI in detecting HCC. Based on the Bayers’ theorem, the sensitivity of CT scan and MRI is 81% and 94% respectively. The specificity of CT scan and MRI is 40% and 90% respectively. The positive predictive value of CT scan and MRI is 90% and 98% respectively. The negative predictive value of CT scan and MRI is 25% and 69% respectively. Diagnostic accuracy of CT scan and MRI in detecting HCC is 76% and 93% respectively. From the result, it showed that CT scan and MRI have higher sensitivity in detecting HCC. However, result was found MRI is more sensitive in detecting small HCC lesion less than 2 cm. Conclusion: CT scan and MRI show similar diagnostic performance for the detection of HCC. However, the advancement in MRI technologies and use of gadoxetix acidenhanced MRI improve the sensitivity in the detection of HCC lesion less than 2 cm in diameter. 2015 Thesis NonPeerReviewed text en http://ir.uitm.edu.my/id/eprint/22284/1/TD_NURAIN%20OSMAN%20HS%20B%2015_5.pdf Osman, Nurain (2015) The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman. Degree thesis, Universiti Teknologi MARA, Selangor, Puncak Alam Campus.
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Medical technology Cancer Diseases of the lungs Radiography Radiographic magnification
spellingShingle	Medical technology Cancer Diseases of the lungs Radiography Radiographic magnification Osman, Nurain The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
description	Purpose: The aim of this thesis was to determine the diagnostic accuracy as well as the sensitivity of CT scan and MRI in detecting hepatocellular carcinoma HCC). Methodology: This is a retrospective study to identify the sensitivity and specificity of CT scan and MRI in detecting HCC. The study was done at Diagnostic and Radiology Department, Selayang Hospital. The time frame for the sample data collection was taken from January 2013 until March 2015. 74 samples were selected based on the inclusion criteria of the study. The patient data selections were strictly the patients who underwent for both CT scan and MRI for detection of HCC. The reference of standard that was used to confirm the presence of the HCC included other interventional findings such as percutaneous biopsy, surgical resection and liver transplant. Result: The results were used in Bayers’ theorem to calculate the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of CT scan and MRI in detecting HCC. Based on the Bayers’ theorem, the sensitivity of CT scan and MRI is 81% and 94% respectively. The specificity of CT scan and MRI is 40% and 90% respectively. The positive predictive value of CT scan and MRI is 90% and 98% respectively. The negative predictive value of CT scan and MRI is 25% and 69% respectively. Diagnostic accuracy of CT scan and MRI in detecting HCC is 76% and 93% respectively. From the result, it showed that CT scan and MRI have higher sensitivity in detecting HCC. However, result was found MRI is more sensitive in detecting small HCC lesion less than 2 cm. Conclusion: CT scan and MRI show similar diagnostic performance for the detection of HCC. However, the advancement in MRI technologies and use of gadoxetix acidenhanced MRI improve the sensitivity in the detection of HCC lesion less than 2 cm in diameter.
format	Thesis
author	Osman, Nurain
author_facet	Osman, Nurain
author_sort	Osman, Nurain
title	The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_short	The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_full	The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_fullStr	The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_full_unstemmed	The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman
title_sort	efficacy of computed tomography (ct) scan and magnetic resonance imaging (mri) in detecting hepatocellular carcinoma (hcc) : retrospective study / nurain osman
publishDate	2015
url	http://ir.uitm.edu.my/id/eprint/22284/ http://ir.uitm.edu.my/id/eprint/22284/1/TD_NURAIN%20OSMAN%20HS%20B%2015_5.pdf
first_indexed	2023-09-18T23:08:21Z
last_indexed	2023-09-18T23:08:21Z
_version_	1777418634410328064

The efficacy of Computed Tomography (CT) scan and Magnetic Resonance Imaging (MRI) in detecting Hepatocellular Carcinoma (HCC) : Retrospective Study / Nurain Osman

Similar Items