Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]

Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]

Introduction: Axillary malodor is caused by microbial biotransformation of non-smelling molecules present in apocrine secretions, into volatile odorous molecules. This study aimed to determine the antimicrobial activities of potassium aluminium salts (alum) against four malodor-producing axillary ba...

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Main Authors: Al-Talib, Hassanain, Mohd Nasir, Nur Izzati Syamimi, Yaziz, Hafizuddin, Zulkafli, Nur Fatihah, Adani, Nur Aqidah, Noor Rashidi, Ahmad Ikhwan, Murugaiah, Chandrika, Shaari, Syahrul Azlin
Format: Article
Language:English
Published: Faculty of Medicine 2016
Subjects:
RC Internal Medicine
Specialties of internal medicine
Online Access:http://ir.uitm.edu.my/id/eprint/14924/
http://ir.uitm.edu.my/id/eprint/14924/
http://ir.uitm.edu.my/id/eprint/14924/1/AJ_HASSANAIN%20AL-TALIB%20JCHS%2016.pdf
id uitm-14924
recordtype eprints
spelling uitm-149242016-10-27T15:46:18Z http://ir.uitm.edu.my/id/eprint/14924/ Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.] Al-Talib, Hassanain Mohd Nasir, Nur Izzati Syamimi Yaziz, Hafizuddin Zulkafli, Nur Fatihah Adani, Nur Aqidah Noor Rashidi, Ahmad Ikhwan Murugaiah, Chandrika Shaari, Syahrul Azlin RC Internal Medicine Specialties of internal medicine Introduction: Axillary malodor is caused by microbial biotransformation of non-smelling molecules present in apocrine secretions, into volatile odorous molecules. This study aimed to determine the antimicrobial activities of potassium aluminium salts (alum) against four malodor-producing axillary bacterial flora, as an alternative natural product for reducing axillary malodor. Methods: The antimicrobial activity of alum against axillary bacterial flora [Micrococcus luteus (ATCC 49732) (M. luteus), Staphylococcus epidermidis (ATCC 14990) (S. epidermidis), Corynebacterium xerosis (ATCC BAA-1293) C. xerosis and Bacilus subtilis (ATCC 19659) (B. subtilis)], was tested in vitro using broth dilution method for different concentrations (0.937 – 20mg/mL) on Luria-Bertani broth. Subculture was done to determine colony-forming units (CFUs) and the minimum inhibitory concentrations (MICs). Results: Alum showed excellent inhibitory effects on all tested bacteria. The lowest MIC of alum was against C. xerosis, at 1.88 mg/mL. M. luteus, B. subtilis and S.epidermidis showed a higher MIC of 3.75, 5.00 and 7.50 mg/mL, respectively. All of the tested bacteria were completely inhibited at a concentration of 7.50 mg/mL. Conclusions: This study revealed that alum has excellent antimicrobial effects against axillary malodor -producing bacteria and is recommended to be used either directly by topical application or as an active ingredient in deodorants and antiperspirants. Faculty of Medicine 2016 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/14924/1/AJ_HASSANAIN%20AL-TALIB%20JCHS%2016.pdf Al-Talib, Hassanain and Mohd Nasir, Nur Izzati Syamimi and Yaziz, Hafizuddin and Zulkafli, Nur Fatihah and Adani, Nur Aqidah and Noor Rashidi, Ahmad Ikhwan and Murugaiah, Chandrika and Shaari, Syahrul Azlin (2016) Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]. Journal of Clinical and Health Sciences, 1 (1). pp. 59-63. ISSN 0127-984X http://jchs-medicine.uitm.edu.my/
repository_type Digital Repository
institution_category Local University
institution Universiti Teknologi MARA
building UiTM Institutional Repository
collection Online Access
language English
topic RC Internal Medicine
Specialties of internal medicine
spellingShingle RC Internal Medicine
Specialties of internal medicine
Al-Talib, Hassanain
Mohd Nasir, Nur Izzati Syamimi
Yaziz, Hafizuddin
Zulkafli, Nur Fatihah
Adani, Nur Aqidah
Noor Rashidi, Ahmad Ikhwan
Murugaiah, Chandrika
Shaari, Syahrul Azlin
Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]
description Introduction: Axillary malodor is caused by microbial biotransformation of non-smelling molecules present in apocrine secretions, into volatile odorous molecules. This study aimed to determine the antimicrobial activities of potassium aluminium salts (alum) against four malodor-producing axillary bacterial flora, as an alternative natural product for reducing axillary malodor. Methods: The antimicrobial activity of alum against axillary bacterial flora [Micrococcus luteus (ATCC 49732) (M. luteus), Staphylococcus epidermidis (ATCC 14990) (S. epidermidis), Corynebacterium xerosis (ATCC BAA-1293) C. xerosis and Bacilus subtilis (ATCC 19659) (B. subtilis)], was tested in vitro using broth dilution method for different concentrations (0.937 – 20mg/mL) on Luria-Bertani broth. Subculture was done to determine colony-forming units (CFUs) and the minimum inhibitory concentrations (MICs). Results: Alum showed excellent inhibitory effects on all tested bacteria. The lowest MIC of alum was against C. xerosis, at 1.88 mg/mL. M. luteus, B. subtilis and S.epidermidis showed a higher MIC of 3.75, 5.00 and 7.50 mg/mL, respectively. All of the tested bacteria were completely inhibited at a concentration of 7.50 mg/mL. Conclusions: This study revealed that alum has excellent antimicrobial effects against axillary malodor -producing bacteria and is recommended to be used either directly by topical application or as an active ingredient in deodorants and antiperspirants.
format Article
author Al-Talib, Hassanain
Mohd Nasir, Nur Izzati Syamimi
Yaziz, Hafizuddin
Zulkafli, Nur Fatihah
Adani, Nur Aqidah
Noor Rashidi, Ahmad Ikhwan
Murugaiah, Chandrika
Shaari, Syahrul Azlin
author_facet Al-Talib, Hassanain
Mohd Nasir, Nur Izzati Syamimi
Yaziz, Hafizuddin
Zulkafli, Nur Fatihah
Adani, Nur Aqidah
Noor Rashidi, Ahmad Ikhwan
Murugaiah, Chandrika
Shaari, Syahrul Azlin
author_sort Al-Talib, Hassanain
title Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]
title_short Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]
title_full Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]
title_fullStr Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]
title_full_unstemmed Potassium aluminium sulphate (Alum) inhibits growth of human axillary malodor-producing skin flora in vitro / Hassanain Al-Talib … [et al.]
title_sort potassium aluminium sulphate (alum) inhibits growth of human axillary malodor-producing skin flora in vitro / hassanain al-talib … [et al.]
publisher Faculty of Medicine
publishDate 2016
url http://ir.uitm.edu.my/id/eprint/14924/
http://ir.uitm.edu.my/id/eprint/14924/
http://ir.uitm.edu.my/id/eprint/14924/1/AJ_HASSANAIN%20AL-TALIB%20JCHS%2016.pdf
first_indexed 2023-09-18T22:52:43Z
last_indexed 2023-09-18T22:52:43Z
_version_ 1777417650937266176

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