Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek

Malaria parasites, Plasmodium can infect a wide range of hosts including humans and rodents. There are two copies of mitogen activated protein kinases (MAPKs) in Plasmodium, namely MAPK1 and MAPK2. The MAPKs have been studied extensively in the human Plasmodium, P. falciparum. However, the MAPKs fro...

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Main Authors:	Raja Yahya, Mohd Fakharul Zaman, Mohd Sidek, Hasidah
Format:	Article
Language:	English
Published:	Research Management Institute 2012
Subjects:	Protein kinases Plasmodium falciparum Malaria
Online Access:	http://ir.uitm.edu.my/id/eprint/12954/ http://ir.uitm.edu.my/id/eprint/12954/1/AJ_MOHD%20FAKHARUL%20ZAMAN%20RAJA%20YAHYA%20SRJ%2012%201.pdf

id	uitm-12954
recordtype	eprints
spelling	uitm-129542017-02-21T03:53:15Z http://ir.uitm.edu.my/id/eprint/12954/ Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek Raja Yahya, Mohd Fakharul Zaman Mohd Sidek, Hasidah Protein kinases Plasmodium falciparum Malaria Malaria parasites, Plasmodium can infect a wide range of hosts including humans and rodents. There are two copies of mitogen activated protein kinases (MAPKs) in Plasmodium, namely MAPK1 and MAPK2. The MAPKs have been studied extensively in the human Plasmodium, P. falciparum. However, the MAPKs from other Plasmodium species have not been characterized and it is therefore the premise of presented study to characterize the MAPKs from other Plasmodium species-P. vivax, P. knowlesi, P. berghei, P. chabaudi and P.yoelli using a series of publicly available bioinformatic tools. In silico data indicates that all Plasmodium MAPKs are nuclear-localizedandcontain both a nuclear localization signal (NLS) anda Leucine-rich nuclear export signal (NES). The activation motifs ofTDYand TSH werefound to befully conserved in Plasmodium MAPK1 and MAPK2, respectively. Research Management Institute 2012 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/12954/1/AJ_MOHD%20FAKHARUL%20ZAMAN%20RAJA%20YAHYA%20SRJ%2012%201.pdf Raja Yahya, Mohd Fakharul Zaman and Mohd Sidek, Hasidah (2012) Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek. Scientific Research Journal, 9 (1). pp. 1-14. ISSN 1675-7009
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Teknologi MARA
building	UiTM Institutional Repository
collection	Online Access
language	English
topic	Protein kinases Plasmodium falciparum Malaria
spellingShingle	Protein kinases Plasmodium falciparum Malaria Raja Yahya, Mohd Fakharul Zaman Mohd Sidek, Hasidah Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
description	Malaria parasites, Plasmodium can infect a wide range of hosts including humans and rodents. There are two copies of mitogen activated protein kinases (MAPKs) in Plasmodium, namely MAPK1 and MAPK2. The MAPKs have been studied extensively in the human Plasmodium, P. falciparum. However, the MAPKs from other Plasmodium species have not been characterized and it is therefore the premise of presented study to characterize the MAPKs from other Plasmodium species-P. vivax, P. knowlesi, P. berghei, P. chabaudi and P.yoelli using a series of publicly available bioinformatic tools. In silico data indicates that all Plasmodium MAPKs are nuclear-localizedandcontain both a nuclear localization signal (NLS) anda Leucine-rich nuclear export signal (NES). The activation motifs ofTDYand TSH werefound to befully conserved in Plasmodium MAPK1 and MAPK2, respectively.
format	Article
author	Raja Yahya, Mohd Fakharul Zaman Mohd Sidek, Hasidah
author_facet	Raja Yahya, Mohd Fakharul Zaman Mohd Sidek, Hasidah
author_sort	Raja Yahya, Mohd Fakharul Zaman
title	Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
title_short	Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
title_full	Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
title_fullStr	Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
title_full_unstemmed	Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
title_sort	comparative study on mitogen activated protein kinase of plasmodium species by using in silico method / mohd fakharul zaman raja yahya and hasidah mohd sidek
publisher	Research Management Institute
publishDate	2012
url	http://ir.uitm.edu.my/id/eprint/12954/ http://ir.uitm.edu.my/id/eprint/12954/1/AJ_MOHD%20FAKHARUL%20ZAMAN%20RAJA%20YAHYA%20SRJ%2012%201.pdf
first_indexed	2023-09-18T22:49:37Z
last_indexed	2023-09-18T22:49:37Z
_version_	1777417456015376384

Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek

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