FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar

Flavonoids are used widely in the pharmaceutical industry due to their anti-oxidative and anti-inflammatory properties. However, most of the flavonoids are poorly water-soluble. These experiments were conducted to prepare the inclusion complex of β-Cyclodextrin with selected flavonoids such as Querc...

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Main Authors: Khosim, Noor Amilia, Abdullah, Ainnie Rahayu, Mokhtar, Marina
Format: Article
Language:English
Published: Universiti Teknologi MARA, Pulau Pinang 2015
Subjects:
Online Access:http://ir.uitm.edu.my/id/eprint/11993/
http://ir.uitm.edu.my/id/eprint/11993/1/AJ_NOOR%20AMILIA%20KHOSIM%20EAJ%2015.pdf
id uitm-11993
recordtype eprints
spelling uitm-119932016-07-26T17:02:42Z http://ir.uitm.edu.my/id/eprint/11993/ FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar Khosim, Noor Amilia Abdullah, Ainnie Rahayu Mokhtar, Marina RS Pharmacy and materia medica Pharmaceutical dosage forms Flavonoids are used widely in the pharmaceutical industry due to their anti-oxidative and anti-inflammatory properties. However, most of the flavonoids are poorly water-soluble. These experiments were conducted to prepare the inclusion complex of β-Cyclodextrin with selected flavonoids such as Quercetin, Naringenin, 3-Hydroxyflavone and Chrysin. The methods used in complexing the host and guest molecules are modified physical mixture, kneading and freeze drying method by using the molar ratio of 1:1. The complexations of the flavonoids tested were analyzed by the Fourier Transform Infrared (FT-IR)spectroscopy. Analysis results suggested that the best method to complex β-Cyclodextrin with Quercetin and Chrysin, were via modified kneading method. Complexation of Naringenin and 3-Hydroxyflavone was best done via modified freeze drying and physical mixture method respectively. Universiti Teknologi MARA, Pulau Pinang 2015 Article PeerReviewed text en http://ir.uitm.edu.my/id/eprint/11993/1/AJ_NOOR%20AMILIA%20KHOSIM%20EAJ%2015.pdf Khosim, Noor Amilia and Abdullah, Ainnie Rahayu and Mokhtar, Marina (2015) FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar. Esteem Academic Journal, 11 (1). pp. 72-80. ISSN 1675-7939
repository_type Digital Repository
institution_category Local University
institution Universiti Teknologi MARA
building UiTM Institutional Repository
collection Online Access
language English
topic RS Pharmacy and materia medica
Pharmaceutical dosage forms
spellingShingle RS Pharmacy and materia medica
Pharmaceutical dosage forms
Khosim, Noor Amilia
Abdullah, Ainnie Rahayu
Mokhtar, Marina
FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar
description Flavonoids are used widely in the pharmaceutical industry due to their anti-oxidative and anti-inflammatory properties. However, most of the flavonoids are poorly water-soluble. These experiments were conducted to prepare the inclusion complex of β-Cyclodextrin with selected flavonoids such as Quercetin, Naringenin, 3-Hydroxyflavone and Chrysin. The methods used in complexing the host and guest molecules are modified physical mixture, kneading and freeze drying method by using the molar ratio of 1:1. The complexations of the flavonoids tested were analyzed by the Fourier Transform Infrared (FT-IR)spectroscopy. Analysis results suggested that the best method to complex β-Cyclodextrin with Quercetin and Chrysin, were via modified kneading method. Complexation of Naringenin and 3-Hydroxyflavone was best done via modified freeze drying and physical mixture method respectively.
format Article
author Khosim, Noor Amilia
Abdullah, Ainnie Rahayu
Mokhtar, Marina
author_facet Khosim, Noor Amilia
Abdullah, Ainnie Rahayu
Mokhtar, Marina
author_sort Khosim, Noor Amilia
title FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar
title_short FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar
title_full FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar
title_fullStr FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar
title_full_unstemmed FT-IR analysis on the inclusion complex of Β-Cyclodextrin with quercetin, naringenin, 3-Hydroxyflavone and chrysin via different preparation methods / Noor Amilia Khosim, Ainnie Rahayu Abdullah and Marina Mokhtar
title_sort ft-ir analysis on the inclusion complex of β-cyclodextrin with quercetin, naringenin, 3-hydroxyflavone and chrysin via different preparation methods / noor amilia khosim, ainnie rahayu abdullah and marina mokhtar
publisher Universiti Teknologi MARA, Pulau Pinang
publishDate 2015
url http://ir.uitm.edu.my/id/eprint/11993/
http://ir.uitm.edu.my/id/eprint/11993/1/AJ_NOOR%20AMILIA%20KHOSIM%20EAJ%2015.pdf
first_indexed 2023-09-18T22:48:49Z
last_indexed 2023-09-18T22:48:49Z
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