Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues

HIV prevention research has shifted to the evaluation of combination prevention programs whereby biomedical, behavioral, and structural interventions are implemented concurrently to maximize synergies among interventions. However, these kinds of combination prevention packages, particularly when imp...

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Main Authors:	Padian, N. S., McCoy, S. I., Manian, S., Wilson, D., Schwartlander, B., Bertozzi, S. M.
Format:	Journal Article
Language:	EN
Published:	2012
Online Access:	http://hdl.handle.net/10986/5123

id	okr-10986-5123
recordtype	oai_dc
spelling	okr-10986-51232021-04-23T14:02:21Z Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues Padian, N. S. McCoy, S. I. Manian, S. Wilson, D. Schwartlander, B. Bertozzi, S. M. HIV prevention research has shifted to the evaluation of combination prevention programs whereby biomedical, behavioral, and structural interventions are implemented concurrently to maximize synergies among interventions. However, these kinds of combination prevention packages, particularly when implemented at scale, pose significant evaluation challenges, including how best to determine impact and how and whether to measure the effectiveness of component strategies. In addition, methodological challenges unique to HIV infection such as the absence of a reliable incidence assay, the lack of naive control groups, and no suitable surrogates further complicate rigorous evaluation. In this commentary, we discuss the key considerations for planning impact evaluations of combination HIV prevention programs in light of these challenges, including defining the evaluable package, determining which component programs require independent assessment of impact, choosing study designs with valid counterfactuals, selecting appropriate outcomes of interest, and the importance of mid-course program corrections. 2012-03-30T07:31:25Z 2012-03-30T07:31:25Z 2011 Journal Article J Acquir Immune Defic Syndr 1944-7884 (Electronic) 1525-4135 (Linking) http://hdl.handle.net/10986/5123 EN http://creativecommons.org/licenses/by-nc-nd/3.0/igo World Bank Journal Article
repository_type	Digital Repository
institution_category	Foreign Institution
institution	Digital Repositories
building	World Bank Open Knowledge Repository
collection	World Bank
language	EN
relation	http://creativecommons.org/licenses/by-nc-nd/3.0/igo
description	HIV prevention research has shifted to the evaluation of combination prevention programs whereby biomedical, behavioral, and structural interventions are implemented concurrently to maximize synergies among interventions. However, these kinds of combination prevention packages, particularly when implemented at scale, pose significant evaluation challenges, including how best to determine impact and how and whether to measure the effectiveness of component strategies. In addition, methodological challenges unique to HIV infection such as the absence of a reliable incidence assay, the lack of naive control groups, and no suitable surrogates further complicate rigorous evaluation. In this commentary, we discuss the key considerations for planning impact evaluations of combination HIV prevention programs in light of these challenges, including defining the evaluable package, determining which component programs require independent assessment of impact, choosing study designs with valid counterfactuals, selecting appropriate outcomes of interest, and the importance of mid-course program corrections.
format	Journal Article
author	Padian, N. S. McCoy, S. I. Manian, S. Wilson, D. Schwartlander, B. Bertozzi, S. M.
spellingShingle	Padian, N. S. McCoy, S. I. Manian, S. Wilson, D. Schwartlander, B. Bertozzi, S. M. Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues
author_facet	Padian, N. S. McCoy, S. I. Manian, S. Wilson, D. Schwartlander, B. Bertozzi, S. M.
author_sort	Padian, N. S.
title	Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues
title_short	Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues
title_full	Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues
title_fullStr	Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues
title_full_unstemmed	Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues
title_sort	evaluation of large-scale combination hiv prevention programs : essential issues
publishDate	2012
url	http://hdl.handle.net/10986/5123
_version_	1764394032602021888

Evaluation of Large-Scale Combination HIV Prevention Programs : Essential Issues

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