The Use of Placebo in a Trial of Rectal Artesunate as Initial Treatment for Severe Malaria Patients En Route to Referral Clinics : Ethical Issues

The Use of Placebo in a Trial of Rectal Artesunate as Initial Treatment for Severe Malaria Patients En Route to Referral Clinics : Ethical Issues

Placebo-controlled trials are controversial when individuals might be denied existing beneficial medical interventions. In the case of malaria, most patients die in rural villages without healthcare facilities. An artesunate suppository that can be given by minimally skilled persons might be of valu...

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Bibliographic Details
Main Authors: Kitua, A., Folb, P., Warsame, M., Binka, F., Faiz, A., Ribeiro, I., Peto, T., Gyapong, J., Yunus, E. B., Rahman, R., Baiden, F., Clerk, C., Mrango, Z., Makasi, C., Kimbute, O., Hossain, A., Samad, R., Gomes, M.
Format: Journal Article
Language:EN
Published: 2012
Subjects:
Rectal Administration
Antimalarials
Artemisinins
Health Services Accessibility
Humans
Malaria
Medication Adherence
Placebos
Randomized Controlled Trials as Topic
Referral and Consultation
Rural Health
Suppositories
Online Access:http://hdl.handle.net/10986/5100

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