A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique

Economic and epidemiological data collected in Beira, Mozambique, are used to conduct this first social cost–benefit analysis for cholera vaccination in Sub-Saharan Africa. The analysis compares the net economic benefits of three immunization strategies with and without user fees: school-based vacci...

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Main Authors: Jeuland, Marc, Lucas, Marcelino, Clemens, John, Whittington, Dale
Format: Journal Article
Published: World Bank 2012
Subjects:
Online Access:http://hdl.handle.net/10986/4502
id okr-10986-4502
recordtype oai_dc
spelling okr-10986-45022021-04-23T14:02:18Z A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique Jeuland, Marc Lucas, Marcelino Clemens, John Whittington, Dale acute dehydration age groups cholera disability disease disease burden diseases endemic areas epidemics epidemiological data infection natural disasters public health therapy treatment vaccination campaign vaccination program vaccination programs vaccines Economic and epidemiological data collected in Beira, Mozambique, are used to conduct this first social cost–benefit analysis for cholera vaccination in Sub-Saharan Africa. The analysis compares the net economic benefits of three immunization strategies with and without user fees: school-based vaccination for school children only (age 5–14), school-based vaccination for all children (age 1–14), and a mass vaccination campaign for all people older than one year. All options assume the use of a low-cost new-generation oral cholera vaccine. The analysis incorporates the latest knowledge of vaccine effectiveness, including new evidence on the positive externality associated with the resulting herd protection (both protection of unvaccinated individuals and enhanced protection among vaccinated individuals arising from vaccination of a portion of the population). It also uses field data for incidence, benefits (private willingness to pay, public cost of illness), and costs (production, shipping, delivery, private travel costs). Taking herd protection into account has important economic implications. For a wide variety of parameters values, vaccination programs in Beira pass a cost–benefit test. Small school-based programs with and without user fees are very likely to provide net benefits. A mass vaccination campaign without user fees would result in the greatest reduction in the disease burden, but the social costs would likely outweigh the benefits, and such a program would require substantial public sector investment. As user fees increase, mass vaccination becomes much more attractive, and the reduction in disease burden remains above 70 percent at relatively low user fees. 2012-03-30T07:12:38Z 2012-03-30T07:12:38Z 2009-06-30 Journal Article World Bank Economic Review 1564-698X http://hdl.handle.net/10986/4502 CC BY-NC-ND 3.0 IGO http://creativecommons.org/licenses/by-nc-nd/3.0/igo World Bank World Bank Journal Article Mozambique
repository_type Digital Repository
institution_category Foreign Institution
institution Digital Repositories
building World Bank Open Knowledge Repository
collection World Bank
topic acute dehydration
age groups
cholera
disability
disease
disease burden
diseases
endemic areas
epidemics
epidemiological data
infection
natural disasters
public health
therapy
treatment
vaccination campaign
vaccination program
vaccination programs
vaccines
spellingShingle acute dehydration
age groups
cholera
disability
disease
disease burden
diseases
endemic areas
epidemics
epidemiological data
infection
natural disasters
public health
therapy
treatment
vaccination campaign
vaccination program
vaccination programs
vaccines
Jeuland, Marc
Lucas, Marcelino
Clemens, John
Whittington, Dale
A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique
geographic_facet Mozambique
description Economic and epidemiological data collected in Beira, Mozambique, are used to conduct this first social cost–benefit analysis for cholera vaccination in Sub-Saharan Africa. The analysis compares the net economic benefits of three immunization strategies with and without user fees: school-based vaccination for school children only (age 5–14), school-based vaccination for all children (age 1–14), and a mass vaccination campaign for all people older than one year. All options assume the use of a low-cost new-generation oral cholera vaccine. The analysis incorporates the latest knowledge of vaccine effectiveness, including new evidence on the positive externality associated with the resulting herd protection (both protection of unvaccinated individuals and enhanced protection among vaccinated individuals arising from vaccination of a portion of the population). It also uses field data for incidence, benefits (private willingness to pay, public cost of illness), and costs (production, shipping, delivery, private travel costs). Taking herd protection into account has important economic implications. For a wide variety of parameters values, vaccination programs in Beira pass a cost–benefit test. Small school-based programs with and without user fees are very likely to provide net benefits. A mass vaccination campaign without user fees would result in the greatest reduction in the disease burden, but the social costs would likely outweigh the benefits, and such a program would require substantial public sector investment. As user fees increase, mass vaccination becomes much more attractive, and the reduction in disease burden remains above 70 percent at relatively low user fees.
format Journal Article
author Jeuland, Marc
Lucas, Marcelino
Clemens, John
Whittington, Dale
author_facet Jeuland, Marc
Lucas, Marcelino
Clemens, John
Whittington, Dale
author_sort Jeuland, Marc
title A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique
title_short A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique
title_full A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique
title_fullStr A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique
title_full_unstemmed A Cost–Benefit Analysis of Cholera Vaccination Programs in Beira, Mozambique
title_sort cost–benefit analysis of cholera vaccination programs in beira, mozambique
publisher World Bank
publishDate 2012
url http://hdl.handle.net/10986/4502
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