Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study

Detention of people who use drugs into compulsory drug detention centres (CDDCs) is common throughout East and Southeast Asia. Evidence-based pharmacological therapies for treating substance use disorders, such as opioid agonist treatments with methadone, are generally unavailable in these settings....

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Main Authors:	Wegman, Martin P., Altice, Frederick L., Kaur, Sangeeth, Rajandaran, Vanessa, Osornprasop, Sutayut, Wilson, David, Wilson, David P., Kamarulzaman, Adeeba
Format:	Journal Article
Published:	Elsevier 2018
Subjects:	DRUG TREATMENT CENTERS OPIOID ADDICTION DRUG ADDICTION VOLUNTARY COMMITMENT COMPULSORY DETENTION DRUG TESTING PHARMACOLOGICAL THERAPY
Online Access:	http://hdl.handle.net/10986/29360

id	okr-10986-29360
recordtype	oai_dc
spelling	okr-10986-293602021-05-25T10:54:44Z Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study Wegman, Martin P. Altice, Frederick L. Kaur, Sangeeth Rajandaran, Vanessa Osornprasop, Sutayut Wilson, David Wilson, David P. Kamarulzaman, Adeeba DRUG TREATMENT CENTERS OPIOID ADDICTION DRUG ADDICTION VOLUNTARY COMMITMENT COMPULSORY DETENTION DRUG TESTING PHARMACOLOGICAL THERAPY Detention of people who use drugs into compulsory drug detention centres (CDDCs) is common throughout East and Southeast Asia. Evidence-based pharmacological therapies for treating substance use disorders, such as opioid agonist treatments with methadone, are generally unavailable in these settings. We used a unique opportunity where CDDCs coexisted with voluntary drug treatment centres (VTCs) providing methadone in Malaysia to compare the timing and occurrence of opioid relapse (measured using urine drug testing) in individuals transitioning from CDDCs versus methadone maintenance in VTCs. Opioid-dependent individuals in CDDCs are significantly more likely to relapse to opioid use after release, and sooner, than those treated with evidence-based treatments such as methadone, suggesting that CDDCs have no role in the treatment of opioid-use disorders. 2018-02-12T21:57:28Z 2018-02-12T21:57:28Z 2017-02 Journal Article The Lancet Global Health 2214-109X http://hdl.handle.net/10986/29360 CC BY-NC-ND 3.0 IGO http://creativecommons.org/licenses/by-nc-nd/3.0/igo World Bank Elsevier Publications & Research :: Journal Article Publications & Research East Asia and Pacific Malaysia
repository_type	Digital Repository
institution_category	Foreign Institution
institution	Digital Repositories
building	World Bank Open Knowledge Repository
collection	World Bank
topic	DRUG TREATMENT CENTERS OPIOID ADDICTION DRUG ADDICTION VOLUNTARY COMMITMENT COMPULSORY DETENTION DRUG TESTING PHARMACOLOGICAL THERAPY
spellingShingle	DRUG TREATMENT CENTERS OPIOID ADDICTION DRUG ADDICTION VOLUNTARY COMMITMENT COMPULSORY DETENTION DRUG TESTING PHARMACOLOGICAL THERAPY Wegman, Martin P. Altice, Frederick L. Kaur, Sangeeth Rajandaran, Vanessa Osornprasop, Sutayut Wilson, David Wilson, David P. Kamarulzaman, Adeeba Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study
geographic_facet	East Asia and Pacific Malaysia
description	Detention of people who use drugs into compulsory drug detention centres (CDDCs) is common throughout East and Southeast Asia. Evidence-based pharmacological therapies for treating substance use disorders, such as opioid agonist treatments with methadone, are generally unavailable in these settings. We used a unique opportunity where CDDCs coexisted with voluntary drug treatment centres (VTCs) providing methadone in Malaysia to compare the timing and occurrence of opioid relapse (measured using urine drug testing) in individuals transitioning from CDDCs versus methadone maintenance in VTCs. Opioid-dependent individuals in CDDCs are significantly more likely to relapse to opioid use after release, and sooner, than those treated with evidence-based treatments such as methadone, suggesting that CDDCs have no role in the treatment of opioid-use disorders.
format	Journal Article
author	Wegman, Martin P. Altice, Frederick L. Kaur, Sangeeth Rajandaran, Vanessa Osornprasop, Sutayut Wilson, David Wilson, David P. Kamarulzaman, Adeeba
author_facet	Wegman, Martin P. Altice, Frederick L. Kaur, Sangeeth Rajandaran, Vanessa Osornprasop, Sutayut Wilson, David Wilson, David P. Kamarulzaman, Adeeba
author_sort	Wegman, Martin P.
title	Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study
title_short	Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study
title_full	Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study
title_fullStr	Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study
title_full_unstemmed	Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study
title_sort	relapse to opioid use in opioid-dependent individuals released from compulsory drug detention centres compared with those from voluntary methadone treatment centres in malaysia : a two-arm, prospective observational study
publisher	Elsevier
publishDate	2018
url	http://hdl.handle.net/10986/29360
_version_	1764469156008165376

Relapse to Opioid Use in Opioid-Dependent Individuals Released from Compulsory Drug Detention Centres Compared with Those from Voluntary Methadone Treatment Centres in Malaysia : A Two-Arm, Prospective Observational Study

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