Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil

Diseases such as diabetes mellitus and gout are among the chronic diseases affecting worldwide population. Investigation is required to find the alternative approaches to treat these chronic diseases, such as plant based medicine. In this study, lemongrass (Cymbopogan citratus) was chosen and examin...

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Main Authors:	Mirghani, Mohamed Elwathig Saeed, Yahya, Liyana, Jamal, Parveen
Format:	Article
Language:	English
Published:	Faculty of Food Science and Technology, Universiti Putra Malaysia 2012
Subjects:	TA164 Bioengineering TP248.13 Biotechnology
Online Access:	http://irep.iium.edu.my/9787/ http://irep.iium.edu.my/9787/ http://irep.iium.edu.my/9787/7/%2829%29_Mirghani.pdf

id	iium-9787
recordtype	eprints
spelling	iium-97872012-02-16T03:08:45Z http://irep.iium.edu.my/9787/ Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil Mirghani, Mohamed Elwathig Saeed Yahya, Liyana Jamal, Parveen TA164 Bioengineering TP248.13 Biotechnology Diseases such as diabetes mellitus and gout are among the chronic diseases affecting worldwide population. Investigation is required to find the alternative approaches to treat these chronic diseases, such as plant based medicine. In this study, lemongrass (Cymbopogan citratus) was chosen and examined on the basis of their usage in traditional medicines throughout Southeast Asia. GCMS analysis revealed the major constituents of the lemongrass essential oil which compromise 67.769% and 67.328% of the total oil respectively. Total phenolic content of the essential oil was analyzed by Folin Ciocalteau method and the results indicated that highest amount of phenolic content was obtained from essential oil extracted from lemongrasses stalk, with phenolic concentration of 2100.769 mg/l GAE. Anti oxidant activity was examined by DPPH scavenging test and the highest inhibition was obtained by essential oil extracted from lemongrass stalk (89.5%). β-glucosidase inhibition assay was carried out using an in-vitro model for anti diabetic test and lemongrass stalk essential oil showed highest degree of inhibitory activity (89.63%). Anti gout test was examined by xanthine oxidase inhibition (XOI) assay with the maximum percentage of xanthine oxidase inhibition of 81.34% obtained from lemongrass stalk essential oil. Thus this project aimed to find the potentiality of lemongrass essential oil which could be the alternative approach due to adverse effects with the use of synthetic drugs for the treatment of many forms of diseases. Faculty of Food Science and Technology, Universiti Putra Malaysia 2012 Article PeerReviewed application/pdf en http://irep.iium.edu.my/9787/7/%2829%29_Mirghani.pdf Mirghani, Mohamed Elwathig Saeed and Yahya, Liyana and Jamal, Parveen (2012) Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil. International Food Research Journal, 19 (2). pp. 569-575. ISSN 19854668 (P), 22317546 (O) http://www.ifrj.upm.edu.my/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	TA164 Bioengineering TP248.13 Biotechnology
spellingShingle	TA164 Bioengineering TP248.13 Biotechnology Mirghani, Mohamed Elwathig Saeed Yahya, Liyana Jamal, Parveen Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil
description	Diseases such as diabetes mellitus and gout are among the chronic diseases affecting worldwide population. Investigation is required to find the alternative approaches to treat these chronic diseases, such as plant based medicine. In this study, lemongrass (Cymbopogan citratus) was chosen and examined on the basis of their usage in traditional medicines throughout Southeast Asia. GCMS analysis revealed the major constituents of the lemongrass essential oil which compromise 67.769% and 67.328% of the total oil respectively. Total phenolic content of the essential oil was analyzed by Folin Ciocalteau method and the results indicated that highest amount of phenolic content was obtained from essential oil extracted from lemongrasses stalk, with phenolic concentration of 2100.769 mg/l GAE. Anti oxidant activity was examined by DPPH scavenging test and the highest inhibition was obtained by essential oil extracted from lemongrass stalk (89.5%). β-glucosidase inhibition assay was carried out using an in-vitro model for anti diabetic test and lemongrass stalk essential oil showed highest degree of inhibitory activity (89.63%). Anti gout test was examined by xanthine oxidase inhibition (XOI) assay with the maximum percentage of xanthine oxidase inhibition of 81.34% obtained from lemongrass stalk essential oil. Thus this project aimed to find the potentiality of lemongrass essential oil which could be the alternative approach due to adverse effects with the use of synthetic drugs for the treatment of many forms of diseases.
format	Article
author	Mirghani, Mohamed Elwathig Saeed Yahya, Liyana Jamal, Parveen
author_facet	Mirghani, Mohamed Elwathig Saeed Yahya, Liyana Jamal, Parveen
author_sort	Mirghani, Mohamed Elwathig Saeed
title	Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil
title_short	Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil
title_full	Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil
title_fullStr	Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil
title_full_unstemmed	Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil
title_sort	bioactivity analysis of lemongrass (cymbopogan citratus) essential oil
publisher	Faculty of Food Science and Technology, Universiti Putra Malaysia
publishDate	2012
url	http://irep.iium.edu.my/9787/ http://irep.iium.edu.my/9787/ http://irep.iium.edu.my/9787/7/%2829%29_Mirghani.pdf
first_indexed	2023-09-18T20:19:24Z
last_indexed	2023-09-18T20:19:24Z
_version_	1777408005666504704

Bioactivity analysis of lemongrass (Cymbopogan citratus) essential oil

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