Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society

In the recent years, increased understanding of the molecular profiles of non-small cell lung cancer (NSCLC) has allowed for targeted treatment of actionable genetic mutations. The management of NSCLC now requires multiple molecular tests to guide the treatment strategy. In the light of this, there...

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Main Authors:	Rajadurai, Pathmanathan, Cheah, Phaik Leng, How, Soon Hin, Liam, Chong Kin, Ahmad Annuar, Muhammad Azrif, Omar, Norhayati, Othman, Noriah, Mohd Marzuki, Nurhayati, Pang, Yong Kek, Ahmad Bustamam, Ros Suzanna, Tho, Lye Mun
Format:	Article
Language:	English English
Published:	Elsevier Ireland Ltd 2019
Subjects:	RC Internal medicine RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
Online Access:	http://irep.iium.edu.my/79720/ http://irep.iium.edu.my/79720/ http://irep.iium.edu.my/79720/ http://irep.iium.edu.my/79720/1/79720_Molecular%20testing%20for%20advanced%20non-small.pdf http://irep.iium.edu.my/79720/2/79720_Molecular%20testing%20for%20advanced%20non-small_SCOPUS.pdf

id	iium-79720
recordtype	eprints
spelling	iium-797202020-03-20T16:00:54Z http://irep.iium.edu.my/79720/ Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society Rajadurai, Pathmanathan Cheah, Phaik Leng How, Soon Hin Liam, Chong Kin Ahmad Annuar, Muhammad Azrif Omar, Norhayati Othman, Noriah Mohd Marzuki, Nurhayati Pang, Yong Kek Ahmad Bustamam, Ros Suzanna Tho, Lye Mun RC Internal medicine RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System In the recent years, increased understanding of the molecular profiles of non-small cell lung cancer (NSCLC) has allowed for targeted treatment of actionable genetic mutations. The management of NSCLC now requires multiple molecular tests to guide the treatment strategy. In the light of this, there is a need to establish a molecular testing consensus statement for advanced NSCLC patients in Malaysia. This Malaysian consensus statement was developed by a panel of experts, chaired by a pathologist and composed of three other pathologists, four respiratory physicians and three oncologists. It reflects currently available scientific data and adaptations of recommendations from international guidelines to the local landscape. Expert recommendations on different aspects of molecular testing agreed upon by the panel are provided as structured discussions. These recommendations address the appropriate patients and samples to be tested, as well as when and how these tests should be performed. The algorithms for molecular testing in metastatic NSCLC, in the first line setting and upon disease progression beyond first line therapy, were developed. Elsevier Ireland Ltd 2019-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/79720/1/79720_Molecular%20testing%20for%20advanced%20non-small.pdf application/pdf en http://irep.iium.edu.my/79720/2/79720_Molecular%20testing%20for%20advanced%20non-small_SCOPUS.pdf Rajadurai, Pathmanathan and Cheah, Phaik Leng and How, Soon Hin and Liam, Chong Kin and Ahmad Annuar, Muhammad Azrif and Omar, Norhayati and Othman, Noriah and Mohd Marzuki, Nurhayati and Pang, Yong Kek and Ahmad Bustamam, Ros Suzanna and Tho, Lye Mun (2019) Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society. Lung Cancer, 136. pp. 65-73. ISSN 0169-5002 https://www.sciencedirect.com/science/article/pii/S016950021930580X 10.1016/j.lungcan.2019.08.005
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RC Internal medicine RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
spellingShingle	RC Internal medicine RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System Rajadurai, Pathmanathan Cheah, Phaik Leng How, Soon Hin Liam, Chong Kin Ahmad Annuar, Muhammad Azrif Omar, Norhayati Othman, Noriah Mohd Marzuki, Nurhayati Pang, Yong Kek Ahmad Bustamam, Ros Suzanna Tho, Lye Mun Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society
description	In the recent years, increased understanding of the molecular profiles of non-small cell lung cancer (NSCLC) has allowed for targeted treatment of actionable genetic mutations. The management of NSCLC now requires multiple molecular tests to guide the treatment strategy. In the light of this, there is a need to establish a molecular testing consensus statement for advanced NSCLC patients in Malaysia. This Malaysian consensus statement was developed by a panel of experts, chaired by a pathologist and composed of three other pathologists, four respiratory physicians and three oncologists. It reflects currently available scientific data and adaptations of recommendations from international guidelines to the local landscape. Expert recommendations on different aspects of molecular testing agreed upon by the panel are provided as structured discussions. These recommendations address the appropriate patients and samples to be tested, as well as when and how these tests should be performed. The algorithms for molecular testing in metastatic NSCLC, in the first line setting and upon disease progression beyond first line therapy, were developed.
format	Article
author	Rajadurai, Pathmanathan Cheah, Phaik Leng How, Soon Hin Liam, Chong Kin Ahmad Annuar, Muhammad Azrif Omar, Norhayati Othman, Noriah Mohd Marzuki, Nurhayati Pang, Yong Kek Ahmad Bustamam, Ros Suzanna Tho, Lye Mun
author_facet	Rajadurai, Pathmanathan Cheah, Phaik Leng How, Soon Hin Liam, Chong Kin Ahmad Annuar, Muhammad Azrif Omar, Norhayati Othman, Noriah Mohd Marzuki, Nurhayati Pang, Yong Kek Ahmad Bustamam, Ros Suzanna Tho, Lye Mun
author_sort	Rajadurai, Pathmanathan
title	Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society
title_short	Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society
title_full	Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society
title_fullStr	Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society
title_full_unstemmed	Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society
title_sort	molecular testing for advanced non-small cell lung cancer in malaysia: consensus statement from the college of pathologists, academy of medicine malaysia, the malaysian thoracic society, and the malaysian oncological society
publisher	Elsevier Ireland Ltd
publishDate	2019
url	http://irep.iium.edu.my/79720/ http://irep.iium.edu.my/79720/ http://irep.iium.edu.my/79720/ http://irep.iium.edu.my/79720/1/79720_Molecular%20testing%20for%20advanced%20non-small.pdf http://irep.iium.edu.my/79720/2/79720_Molecular%20testing%20for%20advanced%20non-small_SCOPUS.pdf
first_indexed	2023-09-18T21:51:43Z
last_indexed	2023-09-18T21:51:43Z
_version_	1777413813552807936

Molecular testing for advanced non-small cell lung cancer in Malaysia: Consensus statement from the College of Pathologists, Academy of Medicine Malaysia, the Malaysian Thoracic Society, and the Malaysian Oncological Society

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