Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta
Osteogenesis Imperfecta (OI) is a group of genetic disorder that affects the bones. It causes bone to break easily. For severe case, it can lead the patient to death. However, doctors still have no quantitative method to predict fractures. Therefore, this study aims to investigate the fracture ri...
| Main Authors: | , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English English |
| Published: |
IOP Publishing
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/79607/ http://irep.iium.edu.my/79607/ http://irep.iium.edu.my/79607/ http://irep.iium.edu.my/79607/1/79607%20Determination%20of%20Fracture%20Risk%20on%20Patient-specific.pdf http://irep.iium.edu.my/79607/2/79607%20Determination%20of%20Fracture%20Risk%20on%20Patient-specific%20SCOPUS.pdf |
| Summary: | Osteogenesis Imperfecta (OI) is a group of genetic disorder that affects the bones. It
causes bone to break easily. For severe case, it can lead the patient to death. However, doctors
still have no quantitative method to predict fractures. Therefore, this study aims to investigate
the fracture risk for OI femoral bone under load of activities in daily living and various loading
direction. A finite element model reconstructed from radiography CT images was developed.
The variations of daily activities were subjected to the femoral model. In standing and walking
configuration, the model of OI has the ability to perform without having any fracture.
However, during jumping, both configurations cause the OI femoral fractured. We can
conclude that when the OI patients more active in their daily life, the higher chances for
fracture to occur. The risk of fracture increases with increasing the intensity of the activity.
Thus, early prediction of fracture risk could help prevent or treating fracture for OI patients. |
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