Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit

Introduction: The mNUTRIC score is a nutritional assessment tool to identify critically ill patients with high nutritional risk who could benefit from nutritional interventions. This study was conducted to validate the 28-day mortality prognostic performance of the mNUTRIC score in a Malaysian inten...

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Main Authors: Wan Muhd Shukeri, Wan Fadzlina, Saeed, Samiullah, Md Ralib, Azrina, Mat Nor, Mohd Basri
Format: Article
Language:English
English
Published: Malaysian Journal of Nutrition 2019
Subjects:
Online Access:http://irep.iium.edu.my/79023/
http://irep.iium.edu.my/79023/
http://irep.iium.edu.my/79023/
http://irep.iium.edu.my/79023/1/Vol%2025%283%29%207.mjn.2019.0074_Basri.pdf
http://irep.iium.edu.my/79023/7/79023_Validation%20of%20the%2028-day%20mortality_scopus.pdf
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spelling iium-790232020-03-18T01:46:04Z http://irep.iium.edu.my/79023/ Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit Wan Muhd Shukeri, Wan Fadzlina Saeed, Samiullah Md Ralib, Azrina Mat Nor, Mohd Basri RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid Introduction: The mNUTRIC score is a nutritional assessment tool to identify critically ill patients with high nutritional risk who could benefit from nutritional interventions. This study was conducted to validate the 28-day mortality prognostic performance of the mNUTRIC score in a Malaysian intensive care unit (ICU). Methods: This was a retrospective cohort study of adult patients who were consecutively admitted to the ICU from January 2017 to December 2018 for >24 hours. Data were collected on variables required to calculate the mNUTRIC score. Patients with mNUTRIC score ≥5 points were considered to be at high nutritional risk. Main outcome was 28- day mortality from all causes; ICU length of stay (LOS) and prolonged mechanical ventilation (MV) (>2 days) were secondary outcomes. Results: From a total of 432 admissions, 382 (88.4%) patients fulfilled the study criteria. Seventy-seven (20.2%) of these patients were at high nutritional risk. They had longer mean ICU LOS (7.1±7.5 days versus 4.2±4.0 days, p=0.001), greater proportion of prolonged MV (57.1% versus 14.4%, p<0.001) and higher 28-day mortality (44.2% versus 10.2%, p<0.001) compared to patients with low mNUTRIC score (≤4 points). High mNUTRIC score predicted 28-day mortality with area under the curve (AUC) of 0.797 (95% confidence interval: 0.738-0.856). Conclusion: High mNUTRIC score was associated with a higher 28-day mortality. The prognostic performance for 28-day mortality of the mNUTRIC score is clinically valid as indicated by AUC >0.7 and is comparable to the results of other validation studies. In addition, patients with high mNUTRIC score had increased ICU LOS and prolonged MV. Key words: Nutritional status, critically ill, mortality Malaysian Journal of Nutrition 2019-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/79023/1/Vol%2025%283%29%207.mjn.2019.0074_Basri.pdf application/pdf en http://irep.iium.edu.my/79023/7/79023_Validation%20of%20the%2028-day%20mortality_scopus.pdf Wan Muhd Shukeri, Wan Fadzlina and Saeed, Samiullah and Md Ralib, Azrina and Mat Nor, Mohd Basri (2019) Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit. Malaysian Journal of Nutrition, 25 (3). pp. 413-421. ISSN 1394-035X http://nutriweb.org.my/mjn/publication/25-3/Vol%2025(3)%207.mjn.2019.0074%20Wan%20Fadzlina_final%20(online%20first).pdf 10.31246/mjn-2019-0074
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid
spellingShingle RC82 Medical Emergencies, Critical Care, Intensive Care, First Aid
Wan Muhd Shukeri, Wan Fadzlina
Saeed, Samiullah
Md Ralib, Azrina
Mat Nor, Mohd Basri
Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
description Introduction: The mNUTRIC score is a nutritional assessment tool to identify critically ill patients with high nutritional risk who could benefit from nutritional interventions. This study was conducted to validate the 28-day mortality prognostic performance of the mNUTRIC score in a Malaysian intensive care unit (ICU). Methods: This was a retrospective cohort study of adult patients who were consecutively admitted to the ICU from January 2017 to December 2018 for >24 hours. Data were collected on variables required to calculate the mNUTRIC score. Patients with mNUTRIC score ≥5 points were considered to be at high nutritional risk. Main outcome was 28- day mortality from all causes; ICU length of stay (LOS) and prolonged mechanical ventilation (MV) (>2 days) were secondary outcomes. Results: From a total of 432 admissions, 382 (88.4%) patients fulfilled the study criteria. Seventy-seven (20.2%) of these patients were at high nutritional risk. They had longer mean ICU LOS (7.1±7.5 days versus 4.2±4.0 days, p=0.001), greater proportion of prolonged MV (57.1% versus 14.4%, p<0.001) and higher 28-day mortality (44.2% versus 10.2%, p<0.001) compared to patients with low mNUTRIC score (≤4 points). High mNUTRIC score predicted 28-day mortality with area under the curve (AUC) of 0.797 (95% confidence interval: 0.738-0.856). Conclusion: High mNUTRIC score was associated with a higher 28-day mortality. The prognostic performance for 28-day mortality of the mNUTRIC score is clinically valid as indicated by AUC >0.7 and is comparable to the results of other validation studies. In addition, patients with high mNUTRIC score had increased ICU LOS and prolonged MV. Key words: Nutritional status, critically ill, mortality
format Article
author Wan Muhd Shukeri, Wan Fadzlina
Saeed, Samiullah
Md Ralib, Azrina
Mat Nor, Mohd Basri
author_facet Wan Muhd Shukeri, Wan Fadzlina
Saeed, Samiullah
Md Ralib, Azrina
Mat Nor, Mohd Basri
author_sort Wan Muhd Shukeri, Wan Fadzlina
title Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
title_short Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
title_full Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
title_fullStr Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
title_full_unstemmed Validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a Malaysian intensive care unit
title_sort validation of the 28-day mortality prognostic performance of the modified nutrition risk in critically ill score in a malaysian intensive care unit
publisher Malaysian Journal of Nutrition
publishDate 2019
url http://irep.iium.edu.my/79023/
http://irep.iium.edu.my/79023/
http://irep.iium.edu.my/79023/
http://irep.iium.edu.my/79023/1/Vol%2025%283%29%207.mjn.2019.0074_Basri.pdf
http://irep.iium.edu.my/79023/7/79023_Validation%20of%20the%2028-day%20mortality_scopus.pdf
first_indexed 2023-09-18T21:51:11Z
last_indexed 2023-09-18T21:51:11Z
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