Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia

Abstract: Inappropriate use of antibiotics in human and animal is one of the causes of antimicrobial resistance. This study evaluates the prevalence and predictors of antibiotic use among pediatric patients visiting the Emergency Department (ED) in Malaysia. A retrospective cross-sectional study wa...

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Main Authors:	Tham, Daniel Wai Je, Abubakar, Usman, Tangiisuran, Balamurugan
Format:	Article
Language:	English English
Published:	Springer 2020
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/78932/ http://irep.iium.edu.my/78932/ http://irep.iium.edu.my/78932/ http://irep.iium.edu.my/78932/1/10.1007_s00431-019-03560-z.pdf http://irep.iium.edu.my/78932/8/Scopus%20-%20prevalence%20and%20predictors.pdf

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recordtype	eprints
spelling	iium-789322020-02-24T04:24:21Z http://irep.iium.edu.my/78932/ Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia Tham, Daniel Wai Je Abubakar, Usman Tangiisuran, Balamurugan RM Therapeutics. Pharmacology Abstract: Inappropriate use of antibiotics in human and animal is one of the causes of antimicrobial resistance. This study evaluates the prevalence and predictors of antibiotic use among pediatric patients visiting the Emergency Department (ED) in Malaysia. A retrospective cross-sectional study was conducted in the ED of a tertiary hospital. Data of children aged 2 to 11 years who visited the ED from January–May 2015 were extracted from the patient’s assessment forms. A total of 549 children were included in the analysis (median age 5 years) of which 54.3% were boys. Upper respiratory tract infections (URTI) were the most common diagnosis. Antibiotic was prescribed in 43.5% of the children.Children who visited the ED during the weekend (OR, 1.65; 95% confidence interval (CI) 1.13–2.40, P=0.009), those diagnosed with URTI (OR 3.81; 95% CI, 2.45–5.93, P<0.001) and those with a longer duration of fever (OR, 1.31; 95% CI, 1.15–1.48, P<0.001) were more likely to have an antibiotic prescription. Conclusions: Antibiotic was prescribed in more than one-third of children who visited the ED and antibiotic use was associated with visits during the weekend, URTI, and duration of fever. Antimicrobial stewardship program is recommended in the pediatric ED to improve appropriate use of antibiotics. Springer 2020-01-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/78932/1/10.1007_s00431-019-03560-z.pdf application/pdf en http://irep.iium.edu.my/78932/8/Scopus%20-%20prevalence%20and%20predictors.pdf Tham, Daniel Wai Je and Abubakar, Usman and Tangiisuran, Balamurugan (2020) Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia. European Journal of Pediatrics. ISSN 0340-6199 (In Press) https://link.springer.com/article/10.1007%2Fs00431-019-03560-z 10.1007/s00431-019-03560-z
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Tham, Daniel Wai Je Abubakar, Usman Tangiisuran, Balamurugan Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia
description	Abstract: Inappropriate use of antibiotics in human and animal is one of the causes of antimicrobial resistance. This study evaluates the prevalence and predictors of antibiotic use among pediatric patients visiting the Emergency Department (ED) in Malaysia. A retrospective cross-sectional study was conducted in the ED of a tertiary hospital. Data of children aged 2 to 11 years who visited the ED from January–May 2015 were extracted from the patient’s assessment forms. A total of 549 children were included in the analysis (median age 5 years) of which 54.3% were boys. Upper respiratory tract infections (URTI) were the most common diagnosis. Antibiotic was prescribed in 43.5% of the children.Children who visited the ED during the weekend (OR, 1.65; 95% confidence interval (CI) 1.13–2.40, P=0.009), those diagnosed with URTI (OR 3.81; 95% CI, 2.45–5.93, P<0.001) and those with a longer duration of fever (OR, 1.31; 95% CI, 1.15–1.48, P<0.001) were more likely to have an antibiotic prescription. Conclusions: Antibiotic was prescribed in more than one-third of children who visited the ED and antibiotic use was associated with visits during the weekend, URTI, and duration of fever. Antimicrobial stewardship program is recommended in the pediatric ED to improve appropriate use of antibiotics.
format	Article
author	Tham, Daniel Wai Je Abubakar, Usman Tangiisuran, Balamurugan
author_facet	Tham, Daniel Wai Je Abubakar, Usman Tangiisuran, Balamurugan
author_sort	Tham, Daniel Wai Je
title	Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia
title_short	Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia
title_full	Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia
title_fullStr	Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia
title_full_unstemmed	Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia
title_sort	prevalence and predictors of antibiotic use among children visiting the emergency department in a tertiary hospital in malaysia
publisher	Springer
publishDate	2020
url	http://irep.iium.edu.my/78932/ http://irep.iium.edu.my/78932/ http://irep.iium.edu.my/78932/ http://irep.iium.edu.my/78932/1/10.1007_s00431-019-03560-z.pdf http://irep.iium.edu.my/78932/8/Scopus%20-%20prevalence%20and%20predictors.pdf
first_indexed	2023-09-18T21:51:05Z
last_indexed	2023-09-18T21:51:05Z
_version_	1777413774088601600

Prevalence and predictors of antibiotic use among children visiting the Emergency Department in a tertiary hospital in Malaysia

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