Ayer Hitam community participations in conservation: a conceptual paper

Introduction: Bullous pemphigoid is a rare acquired, chronic autoimmune blistering disease; which typically produces tense and large blisters with erosions on skin or mucous membrane. It is primarily affects elderly patients in the fifth to seventh decade of life and can be fatal, particularly...

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Main Authors:	Shalihin, Mohd Shaiful Ehsan, Abd Rahman, Mohd Aizuddin
Format:	Conference or Workshop Item
Language:	English English
Published:	2020
Subjects:	R Medicine (General) RA Public aspects of medicine RC Internal medicine RL Dermatology
Online Access:	http://irep.iium.edu.my/78143/ http://irep.iium.edu.my/78143/ http://irep.iium.edu.my/78143/1/gabapentin%20oral%20pemphigoid.pdf http://irep.iium.edu.my/78143/11/E%20BOOK%201st%20EAST%20COST%20MWHS%202020.pdf

id	iium-78143
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spelling	iium-781432020-01-30T04:38:51Z http://irep.iium.edu.my/78143/ Ayer Hitam community participations in conservation: a conceptual paper Shalihin, Mohd Shaiful Ehsan Abd Rahman, Mohd Aizuddin R Medicine (General) RA Public aspects of medicine RC Internal medicine RL Dermatology Introduction: Bullous pemphigoid is a rare acquired, chronic autoimmune blistering disease; which typically produces tense and large blisters with erosions on skin or mucous membrane. It is primarily affects elderly patients in the fifth to seventh decade of life and can be fatal, particularly in patients who are debilitated, with underlying medical problems or left untreated because of misdiagnosis. There are various factors documented able to facilitate bullous pemphigoid such as physical agents, viral infections and drug intake including gabapentin. Gabapentin is an anticonvulsant drugs, but also widely used in the management of neuropathic pain especially in primary care. Even it is rare, gabapentin has been found to cause bullous pemphigoid from the previous literatures. Nevertheless, the previous reported cases were mainly involving trunks and limbs; spared the oral cavity. Report: We herein report a case of a 66-year-old gentleman, who presented with swollen, itchy and tender upper and lower lips with localized erythematous macular rashes over left side of his face for two days duration. He had a history of taking oral gabapentin 300mg three times a day for one week prior to the onset of the lesions. The drug was prescribed in the primary care clinic for his neuropathic pain secondary to bilateral lower limb atherosclerotic gangrene. Examination revealed multiple bullous over his swollen upper lips with desquamative gingivitis. Other system examinations were unremarkable. The offending drug was immediately ceased and he was then referred to Dermatology team for further evaluation. Result: The diagnosis of Gabapentin-induced bullous pemphigoid was confirmed by clinical assessment and histopathological examination. His symptoms gradually improved after a week commencement of high potency topical corticosteroid. Conclusion: This case illustrates the importance of adequate physical examination including detailed oral examination to look for the pathognomonic features in a case suspected to be drug induced rashes. Indeed, adequate knowledge on the side effect of the possible medication that can induce catastrophe skin problem and prompt action to withhold the precipitating drug is really essential in primary care in order to save the pati ent’ s l i fe. 2020-01-11 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/78143/1/gabapentin%20oral%20pemphigoid.pdf application/pdf en http://irep.iium.edu.my/78143/11/E%20BOOK%201st%20EAST%20COST%20MWHS%202020.pdf Shalihin, Mohd Shaiful Ehsan and Abd Rahman, Mohd Aizuddin (2020) Ayer Hitam community participations in conservation: a conceptual paper. In: 1st East Coast Symposium on Men and Women's Health 2020, 11th-12th January 2020, Kuantan. Pahang. (Unpublished) https://iiumfammed.wixsite.com/menwomenhealth/about
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General) RA Public aspects of medicine RC Internal medicine RL Dermatology
spellingShingle	R Medicine (General) RA Public aspects of medicine RC Internal medicine RL Dermatology Shalihin, Mohd Shaiful Ehsan Abd Rahman, Mohd Aizuddin Ayer Hitam community participations in conservation: a conceptual paper
description	Introduction: Bullous pemphigoid is a rare acquired, chronic autoimmune blistering disease; which typically produces tense and large blisters with erosions on skin or mucous membrane. It is primarily affects elderly patients in the fifth to seventh decade of life and can be fatal, particularly in patients who are debilitated, with underlying medical problems or left untreated because of misdiagnosis. There are various factors documented able to facilitate bullous pemphigoid such as physical agents, viral infections and drug intake including gabapentin. Gabapentin is an anticonvulsant drugs, but also widely used in the management of neuropathic pain especially in primary care. Even it is rare, gabapentin has been found to cause bullous pemphigoid from the previous literatures. Nevertheless, the previous reported cases were mainly involving trunks and limbs; spared the oral cavity. Report: We herein report a case of a 66-year-old gentleman, who presented with swollen, itchy and tender upper and lower lips with localized erythematous macular rashes over left side of his face for two days duration. He had a history of taking oral gabapentin 300mg three times a day for one week prior to the onset of the lesions. The drug was prescribed in the primary care clinic for his neuropathic pain secondary to bilateral lower limb atherosclerotic gangrene. Examination revealed multiple bullous over his swollen upper lips with desquamative gingivitis. Other system examinations were unremarkable. The offending drug was immediately ceased and he was then referred to Dermatology team for further evaluation. Result: The diagnosis of Gabapentin-induced bullous pemphigoid was confirmed by clinical assessment and histopathological examination. His symptoms gradually improved after a week commencement of high potency topical corticosteroid. Conclusion: This case illustrates the importance of adequate physical examination including detailed oral examination to look for the pathognomonic features in a case suspected to be drug induced rashes. Indeed, adequate knowledge on the side effect of the possible medication that can induce catastrophe skin problem and prompt action to withhold the precipitating drug is really essential in primary care in order to save the pati ent’ s l i fe.
format	Conference or Workshop Item
author	Shalihin, Mohd Shaiful Ehsan Abd Rahman, Mohd Aizuddin
author_facet	Shalihin, Mohd Shaiful Ehsan Abd Rahman, Mohd Aizuddin
author_sort	Shalihin, Mohd Shaiful Ehsan
title	Ayer Hitam community participations in conservation: a conceptual paper
title_short	Ayer Hitam community participations in conservation: a conceptual paper
title_full	Ayer Hitam community participations in conservation: a conceptual paper
title_fullStr	Ayer Hitam community participations in conservation: a conceptual paper
title_full_unstemmed	Ayer Hitam community participations in conservation: a conceptual paper
title_sort	ayer hitam community participations in conservation: a conceptual paper
publishDate	2020
url	http://irep.iium.edu.my/78143/ http://irep.iium.edu.my/78143/ http://irep.iium.edu.my/78143/1/gabapentin%20oral%20pemphigoid.pdf http://irep.iium.edu.my/78143/11/E%20BOOK%201st%20EAST%20COST%20MWHS%202020.pdf
first_indexed	2023-09-18T21:50:08Z
last_indexed	2023-09-18T21:50:08Z
_version_	1777413713541726208

Ayer Hitam community participations in conservation: a conceptual paper

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