The use of collagen biomaterial in oral cancer: a systematic review

Introduction: Oral cancer is the sixth most common malignancy in the world. It is a major concern in Southeast Asia primarily due to betel quid chewing, smoking, and alcohol consumption. In Malaysia, oral cancer related cases accounts for 1.55% of the cause of deaths. Despite recent advances in ca...

Full description

Bibliographic Details
Main Authors:	Mohamed Halim, Muhammad Lutfi, Mohd Zayi, Nora Azirah, Mohamad, Mohd Yusof, Arzmi, Mohd Hafiz
Format:	Article
Language:	English
Published:	Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia 2019
Subjects:	QR180 Immunology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:	http://irep.iium.edu.my/78135/ http://irep.iium.edu.my/78135/ http://irep.iium.edu.my/78135/1/78135%20THE%20USE%20OF%20COLLAGEN%20BIOMATERIAL.pdf

id	iium-78135
recordtype	eprints
spelling	iium-781352020-01-20T04:49:40Z http://irep.iium.edu.my/78135/ The use of collagen biomaterial in oral cancer: a systematic review Mohamed Halim, Muhammad Lutfi Mohd Zayi, Nora Azirah Mohamad, Mohd Yusof Arzmi, Mohd Hafiz QR180 Immunology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Introduction: Oral cancer is the sixth most common malignancy in the world. It is a major concern in Southeast Asia primarily due to betel quid chewing, smoking, and alcohol consumption. In Malaysia, oral cancer related cases accounts for 1.55% of the cause of deaths. Despite recent advances in cancer diagnoses and therapies, the survival rate of oral cancer patients only reached 50% in the last few decades. Tissue engineering (TE) principles may provide new technology platforms to study mechanisms of angiogenesis and tumour cell growth as well as potentially tumour cell spreading in cancer research. The use of biomaterial, appropriate cell source and proper signalling molecules are vital components of TE. Collagen biomaterial are widely used scaffold or membrane in oral application. Nevertheless, no review has been performed on the its usage for the study of oral cancer. This study aimed to systematically review the use of collagen scaffold in oral cancer application. Methods: Research articles were searched using Scopus, Pubmed and Web of Science (WOS) databases. The keywords were limited to “collagen membrane OR collagen scaffold” AND “oral cancer”. Results: Initial search yielded 61 papers (Scopus:37, Pubmed: 12, WOS: 12). Further scrutinization of the papers based on the inclusion criteria resulted total of 3 papers. Two of the papers used collagen membrane for regeneration of oral mucosal defect and increment of alveolar ridge height post-surgery. The remaining paper utilize collagen biomaterial as scaffold for the culture of adenoid cystic carcinoma (ACC) cells. All papers reported significant role of collagen biomaterial in terms of tissue formation, healing scaffold and cellular proliferation. Conclusion: Collagen utilization as biomaterial offers potential use for regeneration of oral related structures as well providing useful model for therapeutics anti-cancer research. Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia 2019-11 Article PeerReviewed application/pdf en http://irep.iium.edu.my/78135/1/78135%20THE%20USE%20OF%20COLLAGEN%20BIOMATERIAL.pdf Mohamed Halim, Muhammad Lutfi and Mohd Zayi, Nora Azirah and Mohamad, Mohd Yusof and Arzmi, Mohd Hafiz (2019) The use of collagen biomaterial in oral cancer: a systematic review. Malaysian Journal of Medicine and Health Sciences, 15 (Supplement 8). p. 33. E-ISSN 2636-9346 https://medic.upm.edu.my/upload/dokumen/20191129102937Complete_file_2nd_ICOMOI_2019.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QR180 Immunology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle	QR180 Immunology RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Mohamed Halim, Muhammad Lutfi Mohd Zayi, Nora Azirah Mohamad, Mohd Yusof Arzmi, Mohd Hafiz The use of collagen biomaterial in oral cancer: a systematic review
description	Introduction: Oral cancer is the sixth most common malignancy in the world. It is a major concern in Southeast Asia primarily due to betel quid chewing, smoking, and alcohol consumption. In Malaysia, oral cancer related cases accounts for 1.55% of the cause of deaths. Despite recent advances in cancer diagnoses and therapies, the survival rate of oral cancer patients only reached 50% in the last few decades. Tissue engineering (TE) principles may provide new technology platforms to study mechanisms of angiogenesis and tumour cell growth as well as potentially tumour cell spreading in cancer research. The use of biomaterial, appropriate cell source and proper signalling molecules are vital components of TE. Collagen biomaterial are widely used scaffold or membrane in oral application. Nevertheless, no review has been performed on the its usage for the study of oral cancer. This study aimed to systematically review the use of collagen scaffold in oral cancer application. Methods: Research articles were searched using Scopus, Pubmed and Web of Science (WOS) databases. The keywords were limited to “collagen membrane OR collagen scaffold” AND “oral cancer”. Results: Initial search yielded 61 papers (Scopus:37, Pubmed: 12, WOS: 12). Further scrutinization of the papers based on the inclusion criteria resulted total of 3 papers. Two of the papers used collagen membrane for regeneration of oral mucosal defect and increment of alveolar ridge height post-surgery. The remaining paper utilize collagen biomaterial as scaffold for the culture of adenoid cystic carcinoma (ACC) cells. All papers reported significant role of collagen biomaterial in terms of tissue formation, healing scaffold and cellular proliferation. Conclusion: Collagen utilization as biomaterial offers potential use for regeneration of oral related structures as well providing useful model for therapeutics anti-cancer research.
format	Article
author	Mohamed Halim, Muhammad Lutfi Mohd Zayi, Nora Azirah Mohamad, Mohd Yusof Arzmi, Mohd Hafiz
author_facet	Mohamed Halim, Muhammad Lutfi Mohd Zayi, Nora Azirah Mohamad, Mohd Yusof Arzmi, Mohd Hafiz
author_sort	Mohamed Halim, Muhammad Lutfi
title	The use of collagen biomaterial in oral cancer: a systematic review
title_short	The use of collagen biomaterial in oral cancer: a systematic review
title_full	The use of collagen biomaterial in oral cancer: a systematic review
title_fullStr	The use of collagen biomaterial in oral cancer: a systematic review
title_full_unstemmed	The use of collagen biomaterial in oral cancer: a systematic review
title_sort	use of collagen biomaterial in oral cancer: a systematic review
publisher	Fakulti Perubatan dan Sains Kesihatan, Universiti Putra Malaysia
publishDate	2019
url	http://irep.iium.edu.my/78135/ http://irep.iium.edu.my/78135/ http://irep.iium.edu.my/78135/1/78135%20THE%20USE%20OF%20COLLAGEN%20BIOMATERIAL.pdf
first_indexed	2023-09-18T21:50:07Z
last_indexed	2023-09-18T21:50:07Z
_version_	1777413712376758272

The use of collagen biomaterial in oral cancer: a systematic review

Similar Items