Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines

In continuation of our study of Sumatran plants and bioactivities of their constituents particularly their cytotoxic activities, we re-extracted lichen Stereocaulon graminosum Schaer (Stereocaulaceae), and isolated atranorin (1) and stictic acid (4).. These isolated compounds have been tested for th...

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Main Authors:	Husnunnisa, Husnunnisa, Ismed, Friardi, Bakhtiar, M. Taher, Ichwan, Solachuddin J. A., Bakhtiar, Amri, Arbain, Dayar
Format:	Article
Language:	English English
Published:	Marmara University Press 2019
Subjects:	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/77601/ http://irep.iium.edu.my/77601/ http://irep.iium.edu.my/77601/ http://irep.iium.edu.my/77601/1/pdf_MPJ_704.pdf http://irep.iium.edu.my/77601/7/Scopus%20-%20screening%20of%20some%20sumatran%20medicinal%20plants.pdf

id	iium-77601
recordtype	eprints
spelling	iium-776012019-12-30T06:46:57Z http://irep.iium.edu.my/77601/ Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines Husnunnisa, Husnunnisa Ismed, Friardi Bakhtiar, M. Taher Ichwan, Solachuddin J. A. Bakhtiar, Amri Arbain, Dayar RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works RS Pharmacy and materia medica In continuation of our study of Sumatran plants and bioactivities of their constituents particularly their cytotoxic activities, we re-extracted lichen Stereocaulon graminosum Schaer (Stereocaulaceae), and isolated atranorin (1) and stictic acid (4).. These isolated compounds have been tested for their cytotoxic activities against human breast adenocarcinoma cancer cell (MCF-7) and human oral squamous carcinoma cancer cell (HSC-3) using MTT assay with a slight modification. Some methanolic extracts of the leaves of Elephantopus scaber, Piper betle, Andrographis paniculata, rhizomes of Boesenbergia pandurata, Alpinia galanga, Kaempferia galanga and isolated compounds; ethyl haematommate (2), olivatolic acid (3), deoxyelephantopin (5), andrographolide (6), hydroxychavicol (7), eugenol (8), curcumin (9), pinostrobin (10), pinocembrin (11), alpinetin (12), α-mangostin (13), angiopteroside (14), and stevioside (15) from Sumatran traditional medicinal plants have also been tested. Marmara University Press 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/77601/1/pdf_MPJ_704.pdf application/pdf en http://irep.iium.edu.my/77601/7/Scopus%20-%20screening%20of%20some%20sumatran%20medicinal%20plants.pdf Husnunnisa, Husnunnisa and Ismed, Friardi and Bakhtiar, M. Taher and Ichwan, Solachuddin J. A. and Bakhtiar, Amri and Arbain, Dayar (2019) Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines. Journal of Research in Pharmacy, 23 (4). pp. 770-776. ISSN 2630-6344 http://jrespharm.com/abstract.php?id=704 doi.org/10.12991/jrp.2019.186
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works RS Pharmacy and materia medica
spellingShingle	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works RS Pharmacy and materia medica Husnunnisa, Husnunnisa Ismed, Friardi Bakhtiar, M. Taher Ichwan, Solachuddin J. A. Bakhtiar, Amri Arbain, Dayar Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines
description	In continuation of our study of Sumatran plants and bioactivities of their constituents particularly their cytotoxic activities, we re-extracted lichen Stereocaulon graminosum Schaer (Stereocaulaceae), and isolated atranorin (1) and stictic acid (4).. These isolated compounds have been tested for their cytotoxic activities against human breast adenocarcinoma cancer cell (MCF-7) and human oral squamous carcinoma cancer cell (HSC-3) using MTT assay with a slight modification. Some methanolic extracts of the leaves of Elephantopus scaber, Piper betle, Andrographis paniculata, rhizomes of Boesenbergia pandurata, Alpinia galanga, Kaempferia galanga and isolated compounds; ethyl haematommate (2), olivatolic acid (3), deoxyelephantopin (5), andrographolide (6), hydroxychavicol (7), eugenol (8), curcumin (9), pinostrobin (10), pinocembrin (11), alpinetin (12), α-mangostin (13), angiopteroside (14), and stevioside (15) from Sumatran traditional medicinal plants have also been tested.
format	Article
author	Husnunnisa, Husnunnisa Ismed, Friardi Bakhtiar, M. Taher Ichwan, Solachuddin J. A. Bakhtiar, Amri Arbain, Dayar
author_facet	Husnunnisa, Husnunnisa Ismed, Friardi Bakhtiar, M. Taher Ichwan, Solachuddin J. A. Bakhtiar, Amri Arbain, Dayar
author_sort	Husnunnisa, Husnunnisa
title	Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines
title_short	Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines
title_full	Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines
title_fullStr	Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines
title_full_unstemmed	Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines
title_sort	screening of some sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against mcf-7 and hsc-3 cell lines
publisher	Marmara University Press
publishDate	2019
url	http://irep.iium.edu.my/77601/ http://irep.iium.edu.my/77601/ http://irep.iium.edu.my/77601/ http://irep.iium.edu.my/77601/1/pdf_MPJ_704.pdf http://irep.iium.edu.my/77601/7/Scopus%20-%20screening%20of%20some%20sumatran%20medicinal%20plants.pdf
first_indexed	2023-09-18T21:49:27Z
last_indexed	2023-09-18T21:49:27Z
_version_	1777413670718930944

Screening of some Sumatran medicinal plants and selected secondary metabolites for their cytotoxic potential against MCF-7 and HSC-3 cell lines

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