Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization

Background: Analgesic is commonly used in children but little is known about its patterns of utilization. This study explored the patterns of analgesic prescribing in children. Methods: This cross sectional study used prescription databases of tertiary hospital settings in Malaysia from 2010 to...

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Main Author:	Zin, Che Suraya
Format:	Conference or Workshop Item
Language:	English English English
Published:	2019
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/75877/ http://irep.iium.edu.my/75877/1/191104_main%20page_program.pdf http://irep.iium.edu.my/75877/2/191104_opioid_children%20pres_ten%20years%20opioid_naeem_poster_program.pdf http://irep.iium.edu.my/75877/3/191009-Poster_icprp_children%20prescribing.pdf

id	iium-75877
recordtype	eprints
spelling	iium-758772019-11-12T07:13:48Z http://irep.iium.edu.my/75877/ Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization Zin, Che Suraya RM Therapeutics. Pharmacology Background: Analgesic is commonly used in children but little is known about its patterns of utilization. This study explored the patterns of analgesic prescribing in children. Methods: This cross sectional study used prescription databases of tertiary hospital settings in Malaysia from 2010 to 2016. Prescriptions for nine NSAIDs (diclofenac, ketoprofen, etoricoxib, celecoxib, ibuprofen, indomethacin, mefenamic acid, meloxicam and naproxen), tramadol and five other opioids (morphine, oxycodone, fentanyl, buprenorphine and dihydrocodeine) prescribed for children age < 18 years old were included. Number of annual patients and prescriptions were measured and analysed using Stata v15. Results: During a 7-year study period, a total of 5040 analgesic prescriptions of the nine NSAIDs, tramadol, and five other opioids were prescribed for 2460 paediatric patients (81.8% NSAIDs patients, 17.9% tramadol patients, and 0.3% opioid patients). Ibuprofen was the primary analgesic in young children less than 12 years old (≤2 years old (y.o) (75%), 3-5 y.o (85%) and.6-12 y.o (56.3%)). While there was a wide range of analgesics used in older children (above 12 years old) with the majority for naproxen (13 to 15 y.o (28.2%) and 16 to 17 y.o (28.2%). Other frequently prescribed analgesics for older children included ibuprofen (20.6%) and diclofenac (18.2%)) for 12 to 15 y.o and diclofenac (26.7%) and tramadol (17.6%)) for 16-17 y.o. Conclusion: Ibuprofen was the primary analgesic for children less than 12 years old while there was a wide range of analgesics prescribed for children age above 12 years old including naproxen, diclofenac and tramadol. 2019-10-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/75877/1/191104_main%20page_program.pdf application/pdf en http://irep.iium.edu.my/75877/2/191104_opioid_children%20pres_ten%20years%20opioid_naeem_poster_program.pdf application/pdf en http://irep.iium.edu.my/75877/3/191009-Poster_icprp_children%20prescribing.pdf Zin, Che Suraya (2019) Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization. In: International Conference on Pharmaceutical Research and Pharmacy Practice cum 14th IIUM-MPS Pharmacy Scientific Conference (ICPRP 2019), 19-20th October 2019, Hotel Istana Kuala Lumpur. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Zin, Che Suraya Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
description	Background: Analgesic is commonly used in children but little is known about its patterns of utilization. This study explored the patterns of analgesic prescribing in children. Methods: This cross sectional study used prescription databases of tertiary hospital settings in Malaysia from 2010 to 2016. Prescriptions for nine NSAIDs (diclofenac, ketoprofen, etoricoxib, celecoxib, ibuprofen, indomethacin, mefenamic acid, meloxicam and naproxen), tramadol and five other opioids (morphine, oxycodone, fentanyl, buprenorphine and dihydrocodeine) prescribed for children age < 18 years old were included. Number of annual patients and prescriptions were measured and analysed using Stata v15. Results: During a 7-year study period, a total of 5040 analgesic prescriptions of the nine NSAIDs, tramadol, and five other opioids were prescribed for 2460 paediatric patients (81.8% NSAIDs patients, 17.9% tramadol patients, and 0.3% opioid patients). Ibuprofen was the primary analgesic in young children less than 12 years old (≤2 years old (y.o) (75%), 3-5 y.o (85%) and.6-12 y.o (56.3%)). While there was a wide range of analgesics used in older children (above 12 years old) with the majority for naproxen (13 to 15 y.o (28.2%) and 16 to 17 y.o (28.2%). Other frequently prescribed analgesics for older children included ibuprofen (20.6%) and diclofenac (18.2%)) for 12 to 15 y.o and diclofenac (26.7%) and tramadol (17.6%)) for 16-17 y.o. Conclusion: Ibuprofen was the primary analgesic for children less than 12 years old while there was a wide range of analgesics prescribed for children age above 12 years old including naproxen, diclofenac and tramadol.
format	Conference or Workshop Item
author	Zin, Che Suraya
author_facet	Zin, Che Suraya
author_sort	Zin, Che Suraya
title	Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_short	Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_full	Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_fullStr	Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_full_unstemmed	Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
title_sort	prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization
publishDate	2019
url	http://irep.iium.edu.my/75877/ http://irep.iium.edu.my/75877/1/191104_main%20page_program.pdf http://irep.iium.edu.my/75877/2/191104_opioid_children%20pres_ten%20years%20opioid_naeem_poster_program.pdf http://irep.iium.edu.my/75877/3/191009-Poster_icprp_children%20prescribing.pdf
first_indexed	2023-09-18T21:47:19Z
last_indexed	2023-09-18T21:47:19Z
_version_	1777413536808435712

Prescribing of non-steroidal anti-inflammatory drugs, tramadol and opioids in children: patterns of its utilization

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