Antibacterial activities of piper sarmentosum (kaduk) methanolic extract

Piper sarmentosum or locally known as Kaduk is a tropical herbal plant that is well established for many traditional medicinal purposes. The antibacterial properties of methanolic extract for P. sarmentosum leaves have been investigated in this study. From the disc diffusion test, the methanolic e...

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Main Authors:	Ibrahim, Maizatul Akma, Mohd Nazir, Syaza Sailah
Format:	Article
Language:	English
Published:	UPM 2019
Subjects:	Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/75600/ http://irep.iium.edu.my/75600/ http://irep.iium.edu.my/75600/1/ANTIBACTERIAL%20ACTIVITIES%20OF%20Piper%20sarmentosum%20%28KADUK%29%20METHANOLIC.pdf

id	iium-75600
recordtype	eprints
spelling	iium-756002019-10-29T03:07:48Z http://irep.iium.edu.my/75600/ Antibacterial activities of piper sarmentosum (kaduk) methanolic extract Ibrahim, Maizatul Akma Mohd Nazir, Syaza Sailah Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology Piper sarmentosum or locally known as Kaduk is a tropical herbal plant that is well established for many traditional medicinal purposes. The antibacterial properties of methanolic extract for P. sarmentosum leaves have been investigated in this study. From the disc diffusion test, the methanolic extract of P. sarmentosum was found to be active against Gram-positive bacteria namely Staphylococcus saprophyticus (ATCC 15305) and Staphylococcus aureus (ATCC 25923) with zone of inhibition at 17.1 and 11.3 mm, respectively. Meanwhile, the extract showed no or minimal activity against Gram-negative bacteria (Klebsiella pneumoniae ATCC 700603, Pseudomonas aeroginosa ATCC 27853, Enterococcus aerogenes ATCC 13048, Shigella flexneri IMR S 430/07 B, Salmonella typhimurium IMR S 974/05 B) as well as Gram-positive bacteria of Bacillus subtilis (IMR B145/11C). Accordingly, further study by Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were conducted on S. saprophyticus and S. Aureus. The MIC value of methanolic extract for the tested S. saprophyticus and S. aureus were both at 7.5 mg/mL. The MBC showed bacteriostatic for S. saprophyticus and S. aureus at 15 mg/mL. The result of this study indicated that this Piper plant extract can be potential antibacterial agent in the future if the active component can be identified. UPM 2019-10-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/75600/1/ANTIBACTERIAL%20ACTIVITIES%20OF%20Piper%20sarmentosum%20%28KADUK%29%20METHANOLIC.pdf Ibrahim, Maizatul Akma and Mohd Nazir, Syaza Sailah (2019) Antibacterial activities of piper sarmentosum (kaduk) methanolic extract. Acta Scientifica Malaysia, 3 (2). pp. 21-24. ISSN 2521-5051 E-ISSN 2521-506X http://psasir.upm.edu.my/id/eprint/67754/1/FP%202015%2088%20IR.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology
spellingShingle	Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology Ibrahim, Maizatul Akma Mohd Nazir, Syaza Sailah Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
description	Piper sarmentosum or locally known as Kaduk is a tropical herbal plant that is well established for many traditional medicinal purposes. The antibacterial properties of methanolic extract for P. sarmentosum leaves have been investigated in this study. From the disc diffusion test, the methanolic extract of P. sarmentosum was found to be active against Gram-positive bacteria namely Staphylococcus saprophyticus (ATCC 15305) and Staphylococcus aureus (ATCC 25923) with zone of inhibition at 17.1 and 11.3 mm, respectively. Meanwhile, the extract showed no or minimal activity against Gram-negative bacteria (Klebsiella pneumoniae ATCC 700603, Pseudomonas aeroginosa ATCC 27853, Enterococcus aerogenes ATCC 13048, Shigella flexneri IMR S 430/07 B, Salmonella typhimurium IMR S 974/05 B) as well as Gram-positive bacteria of Bacillus subtilis (IMR B145/11C). Accordingly, further study by Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were conducted on S. saprophyticus and S. Aureus. The MIC value of methanolic extract for the tested S. saprophyticus and S. aureus were both at 7.5 mg/mL. The MBC showed bacteriostatic for S. saprophyticus and S. aureus at 15 mg/mL. The result of this study indicated that this Piper plant extract can be potential antibacterial agent in the future if the active component can be identified.
format	Article
author	Ibrahim, Maizatul Akma Mohd Nazir, Syaza Sailah
author_facet	Ibrahim, Maizatul Akma Mohd Nazir, Syaza Sailah
author_sort	Ibrahim, Maizatul Akma
title	Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
title_short	Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
title_full	Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
title_fullStr	Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
title_full_unstemmed	Antibacterial activities of piper sarmentosum (kaduk) methanolic extract
title_sort	antibacterial activities of piper sarmentosum (kaduk) methanolic extract
publisher	UPM
publishDate	2019
url	http://irep.iium.edu.my/75600/ http://irep.iium.edu.my/75600/ http://irep.iium.edu.my/75600/1/ANTIBACTERIAL%20ACTIVITIES%20OF%20Piper%20sarmentosum%20%28KADUK%29%20METHANOLIC.pdf
first_indexed	2023-09-18T21:46:57Z
last_indexed	2023-09-18T21:46:57Z
_version_	1777413513211281408

Antibacterial activities of piper sarmentosum (kaduk) methanolic extract

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