Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum

Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are t...

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Main Authors:	Zamimi, Nurul Najwa, Ab. Halim, Noorhazayti, Darnis, Deny Susanti, Lestari, Widya, Md Mustafa, Md Muziman Syah
Format:	Article
Language:	English English
Published:	2019
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/75520/ http://irep.iium.edu.my/75520/ http://irep.iium.edu.my/75520/ http://irep.iium.edu.my/75520/1/Najwa%20et%20al.-2019-Gas%20chromatography-mass%20spectrometry.pdf http://irep.iium.edu.my/75520/7/75520_Gas%20chromatography-mass%20spectrometry%20analysis%20of%20phytocomponents%20of%20sargassum%20polycystum_Scopus.pdf

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spelling	iium-755202020-02-27T08:37:12Z http://irep.iium.edu.my/75520/ Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum Zamimi, Nurul Najwa Ab. Halim, Noorhazayti Darnis, Deny Susanti Lestari, Widya Md Mustafa, Md Muziman Syah RM Therapeutics. Pharmacology Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are to evaluate the best extraction solvents for S. polycystum and to determine the percentage of phytocomponents obtained in the n-hexane, dichloromethane (DCM) and methanol extracts of S. polycystum via Gas Chromatography-Mass Spectrometry (GC-MS) analysis. S. polycystum was collected from the coastal area of Sabah, Malaysia. After collection, it was rinsed, dried and extracted with n-hexane, DCM and methanol by soxhlet extraction. The fatty acid compounds (FAME) analysis was done using The Perkin Elmer Turbo Mass Spectrometer. This study showed that methanol is the most efficient solvent as it produced the highest extraction yield with 3.83%, followed by n-hexane with 1.69% and lastly DCM with 0.59% in S. polycystum. On top of that, this study has found 19 phytocomponents in all extraction methods of S. polycystum, which have been proven to possess antibacterial constituents such as palmitic acid, myristic acid, oleic acid, pentadecanoic acid and behenic acid as assessed by GC-MS analysis. 2019 Article PeerReviewed application/pdf en http://irep.iium.edu.my/75520/1/Najwa%20et%20al.-2019-Gas%20chromatography-mass%20spectrometry.pdf application/pdf en http://irep.iium.edu.my/75520/7/75520_Gas%20chromatography-mass%20spectrometry%20analysis%20of%20phytocomponents%20of%20sargassum%20polycystum_Scopus.pdf Zamimi, Nurul Najwa and Ab. Halim, Noorhazayti and Darnis, Deny Susanti and Lestari, Widya and Md Mustafa, Md Muziman Syah (2019) Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum. International Journal of Research in Pharmaceutical Sciences, 10 (4). pp. 2705-2710. ISSN 0975-7538 http://doi.org/10.26452/ijrps.v10i4.1533 doi:10.26452/ijrps.v10i4.1533
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Zamimi, Nurul Najwa Ab. Halim, Noorhazayti Darnis, Deny Susanti Lestari, Widya Md Mustafa, Md Muziman Syah Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
description	Sargassum polycystum is a brown seaweed, which has been reported to contain various phytoconstituents especially antimicrobial properties. However, the study on phytochemical components and biological activities of S. polycystum are yet fully understood. Therefore, the objectives of this study are to evaluate the best extraction solvents for S. polycystum and to determine the percentage of phytocomponents obtained in the n-hexane, dichloromethane (DCM) and methanol extracts of S. polycystum via Gas Chromatography-Mass Spectrometry (GC-MS) analysis. S. polycystum was collected from the coastal area of Sabah, Malaysia. After collection, it was rinsed, dried and extracted with n-hexane, DCM and methanol by soxhlet extraction. The fatty acid compounds (FAME) analysis was done using The Perkin Elmer Turbo Mass Spectrometer. This study showed that methanol is the most efficient solvent as it produced the highest extraction yield with 3.83%, followed by n-hexane with 1.69% and lastly DCM with 0.59% in S. polycystum. On top of that, this study has found 19 phytocomponents in all extraction methods of S. polycystum, which have been proven to possess antibacterial constituents such as palmitic acid, myristic acid, oleic acid, pentadecanoic acid and behenic acid as assessed by GC-MS analysis.
format	Article
author	Zamimi, Nurul Najwa Ab. Halim, Noorhazayti Darnis, Deny Susanti Lestari, Widya Md Mustafa, Md Muziman Syah
author_facet	Zamimi, Nurul Najwa Ab. Halim, Noorhazayti Darnis, Deny Susanti Lestari, Widya Md Mustafa, Md Muziman Syah
author_sort	Zamimi, Nurul Najwa
title	Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_short	Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_full	Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_fullStr	Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_full_unstemmed	Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
title_sort	gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum
publishDate	2019
url	http://irep.iium.edu.my/75520/ http://irep.iium.edu.my/75520/ http://irep.iium.edu.my/75520/ http://irep.iium.edu.my/75520/1/Najwa%20et%20al.-2019-Gas%20chromatography-mass%20spectrometry.pdf http://irep.iium.edu.my/75520/7/75520_Gas%20chromatography-mass%20spectrometry%20analysis%20of%20phytocomponents%20of%20sargassum%20polycystum_Scopus.pdf
first_indexed	2023-09-18T21:46:51Z
last_indexed	2023-09-18T21:46:51Z
_version_	1777413507414753280

Gas chromatography-mass spectrometry analysis of phytocomponents of sargassum polycystum

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