Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads

Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads

Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still have no quantitative method to predi...

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Main Authors: Tan, L.C., Mat Som, Mohd Hanafi, Basaruddin, K.S., Yazid, H., Sulaiman, Abdul Razak, Awang, Mohd. Shukrimi
Format: Article
Language:English
Published: IJENS Publisher 2019
Subjects:
RD701 Orthopedics
Online Access:http://irep.iium.edu.my/75422/
http://irep.iium.edu.my/75422/
http://irep.iium.edu.my/75422/1/Modelling%20of%20Patient-Specific%20Femur%20with%20Osteogenesis%20Imperfecta%20to%20Determine%20the%20Fracture%20Risk%20Under%20Various%20Loads.pdf
id iium-75422
recordtype eprints
spelling iium-754222019-11-21T03:04:52Z http://irep.iium.edu.my/75422/ Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads Tan, L.C. Mat Som, Mohd Hanafi Basaruddin, K.S. Yazid, H. Sulaiman, Abdul Razak Awang, Mohd. Shukrimi RD701 Orthopedics Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still have no quantitative method to predict fractures. Therefore, this project’s purpose is to investigate the OI femoral fracture risk to help prevent fractures. The project consists of three sections; cortical and cancellous segmentation, reconstruction of 3D OI femoral model and finite element analysis (FEA) of the OI femur to obtain fracture risk. The fracture risk in daily activities and the fracture load were examined. All the stress values were judged by the fracture criteria, assumed as 115 MPa. The exercises that exerted force more than 6 times of body weight can cause fractures. In addition, the optimal compressive force and tensile force were 919.7 N and 912.1 N, respectively, while medial and lateral impact were 230.8 N. Cancellous bone was not affected even a fracture happen. Based on these findings, we can conclude that when the OI femur is subjected to lateral or medial forces, the femur breaks easily. The bone can be reconstructed into a solid body without having to separate bone into cortical and cancellous. IJENS Publisher 2019-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/75422/1/Modelling%20of%20Patient-Specific%20Femur%20with%20Osteogenesis%20Imperfecta%20to%20Determine%20the%20Fracture%20Risk%20Under%20Various%20Loads.pdf Tan, L.C. and Mat Som, Mohd Hanafi and Basaruddin, K.S. and Yazid, H. and Sulaiman, Abdul Razak and Awang, Mohd. Shukrimi (2019) Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads. International Journal of Mechanical & Mechatronics Engineering, 19 (4). pp. 100-108. ISSN 2227-2771 E-ISSN 2077-124X http://ijens.org/Vol_19_I_04/192904-5656-IJMME-IJENS.pdf
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RD701 Orthopedics
spellingShingle RD701 Orthopedics
Tan, L.C.
Mat Som, Mohd Hanafi
Basaruddin, K.S.
Yazid, H.
Sulaiman, Abdul Razak
Awang, Mohd. Shukrimi
Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
description Osteogenesis imperfecta (OI) is a fragile bone disease characterized by easy fractures. The femur consists of cortical and cancellous bone, each with different mechanical properties. Bone fractures often occur throughout patients’ lifetime. However, doctors still have no quantitative method to predict fractures. Therefore, this project’s purpose is to investigate the OI femoral fracture risk to help prevent fractures. The project consists of three sections; cortical and cancellous segmentation, reconstruction of 3D OI femoral model and finite element analysis (FEA) of the OI femur to obtain fracture risk. The fracture risk in daily activities and the fracture load were examined. All the stress values were judged by the fracture criteria, assumed as 115 MPa. The exercises that exerted force more than 6 times of body weight can cause fractures. In addition, the optimal compressive force and tensile force were 919.7 N and 912.1 N, respectively, while medial and lateral impact were 230.8 N. Cancellous bone was not affected even a fracture happen. Based on these findings, we can conclude that when the OI femur is subjected to lateral or medial forces, the femur breaks easily. The bone can be reconstructed into a solid body without having to separate bone into cortical and cancellous.
format Article
author Tan, L.C.
Mat Som, Mohd Hanafi
Basaruddin, K.S.
Yazid, H.
Sulaiman, Abdul Razak
Awang, Mohd. Shukrimi
author_facet Tan, L.C.
Mat Som, Mohd Hanafi
Basaruddin, K.S.
Yazid, H.
Sulaiman, Abdul Razak
Awang, Mohd. Shukrimi
author_sort Tan, L.C.
title Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
title_short Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
title_full Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
title_fullStr Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
title_full_unstemmed Modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
title_sort modelling of patient-specific femur with osteogenesis imperfecta to determine the fracture risk under various loads
publisher IJENS Publisher
publishDate 2019
url http://irep.iium.edu.my/75422/
http://irep.iium.edu.my/75422/
http://irep.iium.edu.my/75422/1/Modelling%20of%20Patient-Specific%20Femur%20with%20Osteogenesis%20Imperfecta%20to%20Determine%20the%20Fracture%20Risk%20Under%20Various%20Loads.pdf
first_indexed 2023-09-18T21:46:44Z
last_indexed 2023-09-18T21:46:44Z
_version_ 1777413499542044672

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