Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.

Background/Objective: The study of trabecular bone provides information relating to bone strength. A number of imaging modalities are used to investigate the internal trabecular structure of human bone, including x-ray macroradiography, high resolution-CT (HRCT) and micro-computed tomography (micro-...

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Main Authors:	Yusof, Nurul Asyiqin, Soames, Roger W., Black, Sue M., Craig, Cunningham A.
Format:	Conference or Workshop Item
Language:	English English
Published:	2019
Subjects:	QM Human anatomy
Online Access:	http://irep.iium.edu.my/75204/ http://irep.iium.edu.my/75204/1/Poster%20MAAC%202019%20-%20technique%20in%20analysing%20trabecular%20bone.pdf http://irep.iium.edu.my/75204/7/Dr%20Nurul%20Asyiqin%20Yusof%20poster%20MAAC2019.pdf

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recordtype	eprints
spelling	iium-752042020-01-22T08:28:12Z http://irep.iium.edu.my/75204/ Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method. Yusof, Nurul Asyiqin Soames, Roger W. Black, Sue M. Craig, Cunningham A. QM Human anatomy Background/Objective: The study of trabecular bone provides information relating to bone strength. A number of imaging modalities are used to investigate the internal trabecular structure of human bone, including x-ray macroradiography, high resolution-CT (HRCT) and micro-computed tomography (micro-CT), with many studies focusing on adult bone analysis, including fracture management and osteoporosis-related bone density. However, only a limited number have investigated trabecular microarchitecture in juvenile bone. The purpose of the current study is to introduce a technique of quantifying trabecular bone parameters in the human juvenile sacrum. Methodology: Twenty-six individual human S1 sacra spanning the period from infancy to eight years of age were examined using micro-CT. The images were analysed using Skyscan CTAnalyser (Skyscan CTAn) 1.11, which provides detailed 3-D quantification of trabecular architecture in a targeted region for specific parameters: (i) bone volume fraction (BV/TV (%)), (ii) trabecular thickness (Tb.Th), (iii) trabecular separation (Tb.Sp), (iv) trabecular number (Tb.N), (v) structural model index (SMI) and (vi) degree of anisotropy (DA). Result and Discussion: Areas fo high-density, populated with plate-like trabecular structures are commonly found in high stress regions of the bone, suggesting that the trabecular pattern correlates highly with mechanical properties. The results demonstrated that in S1, the areas of high stress are located at the medial part of the vertebra, while the lateral part (the auricular areas) exhibit sparse bone density. 2019 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/75204/1/Poster%20MAAC%202019%20-%20technique%20in%20analysing%20trabecular%20bone.pdf application/pdf en http://irep.iium.edu.my/75204/7/Dr%20Nurul%20Asyiqin%20Yusof%20poster%20MAAC2019.pdf Yusof, Nurul Asyiqin and Soames, Roger W. and Black, Sue M. and Craig, Cunningham A. (2019) Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method. In: Malaysian Anatomical Association Conference 2019, 4th-5th September 2019, Marina Putrajaya. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QM Human anatomy
spellingShingle	QM Human anatomy Yusof, Nurul Asyiqin Soames, Roger W. Black, Sue M. Craig, Cunningham A. Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.
description	Background/Objective: The study of trabecular bone provides information relating to bone strength. A number of imaging modalities are used to investigate the internal trabecular structure of human bone, including x-ray macroradiography, high resolution-CT (HRCT) and micro-computed tomography (micro-CT), with many studies focusing on adult bone analysis, including fracture management and osteoporosis-related bone density. However, only a limited number have investigated trabecular microarchitecture in juvenile bone. The purpose of the current study is to introduce a technique of quantifying trabecular bone parameters in the human juvenile sacrum. Methodology: Twenty-six individual human S1 sacra spanning the period from infancy to eight years of age were examined using micro-CT. The images were analysed using Skyscan CTAnalyser (Skyscan CTAn) 1.11, which provides detailed 3-D quantification of trabecular architecture in a targeted region for specific parameters: (i) bone volume fraction (BV/TV (%)), (ii) trabecular thickness (Tb.Th), (iii) trabecular separation (Tb.Sp), (iv) trabecular number (Tb.N), (v) structural model index (SMI) and (vi) degree of anisotropy (DA). Result and Discussion: Areas fo high-density, populated with plate-like trabecular structures are commonly found in high stress regions of the bone, suggesting that the trabecular pattern correlates highly with mechanical properties. The results demonstrated that in S1, the areas of high stress are located at the medial part of the vertebra, while the lateral part (the auricular areas) exhibit sparse bone density.
format	Conference or Workshop Item
author	Yusof, Nurul Asyiqin Soames, Roger W. Black, Sue M. Craig, Cunningham A.
author_facet	Yusof, Nurul Asyiqin Soames, Roger W. Black, Sue M. Craig, Cunningham A.
author_sort	Yusof, Nurul Asyiqin
title	Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.
title_short	Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.
title_full	Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.
title_fullStr	Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.
title_full_unstemmed	Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.
title_sort	quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-ct scan and skyscan ctanalyser method.
publishDate	2019
url	http://irep.iium.edu.my/75204/ http://irep.iium.edu.my/75204/1/Poster%20MAAC%202019%20-%20technique%20in%20analysing%20trabecular%20bone.pdf http://irep.iium.edu.my/75204/7/Dr%20Nurul%20Asyiqin%20Yusof%20poster%20MAAC2019.pdf
first_indexed	2023-09-18T21:46:24Z
last_indexed	2023-09-18T21:46:24Z
_version_	1777413478690062336

Quantification technique for analysing juvenile sacral trabecular microarchitecture: a micro-CT scan and Skyscan Ctanalyser method.

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