Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines

Myrmecodia pendens (M. pendens) or also known as Sarang semut is an epiphytic plant which might have potential as a new source of alternative therapeutic agent. Recently, it is reported that M. pendens can inhibit the proliferation of HeLa and MCM- B2 cell lines. We report here for the first time...

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Main Authors:	Irfanita, Nining, Eddie, Shah, Aziz, N.A., Ichwan, Solachuddin J. A., Lestari, Widya
Format:	Conference or Workshop Item
Language:	English English
Published:	Elsevier 2019
Subjects:	RK Dentistry
Online Access:	http://irep.iium.edu.my/75065/ http://irep.iium.edu.my/75065/ http://irep.iium.edu.my/75065/ http://irep.iium.edu.my/75065/9/75065%20%20%20%20%20Preliminary%20investigations%20of%20anti-cancer%20propertie.pdf http://irep.iium.edu.my/75065/8/75065%20Preliminary%20investigations%20of%20anti-cancer%20properties%20SCOPUS.pdf

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recordtype	eprints
spelling	iium-750652019-11-08T02:33:54Z http://irep.iium.edu.my/75065/ Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines Irfanita, Nining Eddie, Shah Aziz, N.A. Ichwan, Solachuddin J. A. Lestari, Widya RK Dentistry Myrmecodia pendens (M. pendens) or also known as Sarang semut is an epiphytic plant which might have potential as a new source of alternative therapeutic agent. Recently, it is reported that M. pendens can inhibit the proliferation of HeLa and MCM- B2 cell lines. We report here for the first time the anti-cancer potential of M. pendens on oral cancer cells derived from human oral cavity, HSC-3 cell lines. MTT assay results showed that M. pendens crude extract markedly induced cytotoxicity on HSC-3 cell lines after 24 h (IC50 = 5 mg/mL) and 48 h (IC50 = 3 mg/ml). The apoptotic activity induced by M. pendens was detected in HSC-3 cell lines by flow cytometry within 24 h. These results suggest that M. pendens may be a potential candidate for oral cancer treatment Elsevier 2019 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/75065/9/75065%20%20%20%20%20Preliminary%20investigations%20of%20anti-cancer%20propertie.pdf application/pdf en http://irep.iium.edu.my/75065/8/75065%20Preliminary%20investigations%20of%20anti-cancer%20properties%20SCOPUS.pdf Irfanita, Nining and Eddie, Shah and Aziz, N.A. and Ichwan, Solachuddin J. A. and Lestari, Widya (2019) Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines. In: Conference on BioMedical and Advanced Materials (Bio-CAM 2017), 28th-29th November 2017, Pulau Langkawi, Kedah. https://www.sciencedirect.com/science/article/pii/S2214785319314592 10.1016/j.matpr.2019.06.110
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RK Dentistry
spellingShingle	RK Dentistry Irfanita, Nining Eddie, Shah Aziz, N.A. Ichwan, Solachuddin J. A. Lestari, Widya Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines
description	Myrmecodia pendens (M. pendens) or also known as Sarang semut is an epiphytic plant which might have potential as a new source of alternative therapeutic agent. Recently, it is reported that M. pendens can inhibit the proliferation of HeLa and MCM- B2 cell lines. We report here for the first time the anti-cancer potential of M. pendens on oral cancer cells derived from human oral cavity, HSC-3 cell lines. MTT assay results showed that M. pendens crude extract markedly induced cytotoxicity on HSC-3 cell lines after 24 h (IC50 = 5 mg/mL) and 48 h (IC50 = 3 mg/ml). The apoptotic activity induced by M. pendens was detected in HSC-3 cell lines by flow cytometry within 24 h. These results suggest that M. pendens may be a potential candidate for oral cancer treatment
format	Conference or Workshop Item
author	Irfanita, Nining Eddie, Shah Aziz, N.A. Ichwan, Solachuddin J. A. Lestari, Widya
author_facet	Irfanita, Nining Eddie, Shah Aziz, N.A. Ichwan, Solachuddin J. A. Lestari, Widya
author_sort	Irfanita, Nining
title	Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines
title_short	Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines
title_full	Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines
title_fullStr	Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines
title_full_unstemmed	Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines
title_sort	preliminary investigations of anti-cancer properties of myrmecodia pendens on human oral cancer hsc-3 cell lines
publisher	Elsevier
publishDate	2019
url	http://irep.iium.edu.my/75065/ http://irep.iium.edu.my/75065/ http://irep.iium.edu.my/75065/ http://irep.iium.edu.my/75065/9/75065%20%20%20%20%20Preliminary%20investigations%20of%20anti-cancer%20propertie.pdf http://irep.iium.edu.my/75065/8/75065%20Preliminary%20investigations%20of%20anti-cancer%20properties%20SCOPUS.pdf
first_indexed	2023-09-18T21:46:14Z
last_indexed	2023-09-18T21:46:14Z
_version_	1777413468186476544

Preliminary investigations of anti-cancer properties of Myrmecodia Pendens on human oral cancer HSC-3 cell lines

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