Insights on the synthesis of asymmetric curcumin derivatives and their biological activities
Curcumin is a small organic molecule with pleiotropic biological activities. However, its multiple structural-pharmacokinetic challenges prevent its development into a clinical drug. Various structural modifications have been made to improve its drug profile. In this review, we focus on the methods...
Main Authors: | Rullah, Malaysia, Mohd Aluwi, Mohd Fadhlizil Fasihi, Khor, Poh Yen, Kok Wai, Lam |
---|---|
Format: | Article |
Language: | English English |
Published: |
Elsevier
2019
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/75023/ http://irep.iium.edu.my/75023/ http://irep.iium.edu.my/75023/ http://irep.iium.edu.my/75023/1/1-s2.0-S0223523419308566-main.pdf http://irep.iium.edu.my/75023/7/75023_Insights%20on%20the%20synthesis%20of%20asymmetric%20curcumin_scopus.pdf |
Similar Items
-
Synthesis, biological evaluation and docking studies of aurone derivatives on Xanthine oxidase enzyme
by: Rullah, Kamal, et al.
Published: (2018) -
Synthesis and SAR studies of new chromone derivatives as Inhibitors of PGE2 production
by: Rullah, Kamal, et al.
Published: (2019) -
Insights on the synthesis of asymmetric curcumin derivatives and their biological activities
by: Poh, Yen Khor, et al.
Published: (2019) -
Suppression of PGE2 production via disruption of MAPK
phosphorylation by unsymmetrical dicarbonyl curcumin
derivatives
by: Mohd Aluwi, Mohd Fadhlizil Fasihi, et al.
Published: (2017) -
Palladium‐catalysed cross‐coupling reactions for the synthesis of chalcones
by: Rullah, Kamal, et al.
Published: (2019)