Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum

Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum

Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp because this genus is a rich source of active secondary metabolites which shows anti-HIV,...

Full description

Bibliographic Details
Main Authors: Aminudin, Nurul Iman, Ahmad, Farediah, Bakhtiar, M. Taher
Format: Article
Language:English
English
Published: The Malaysian Analytical Sciences Society 2019
Subjects:
QD Chemistry
Online Access:http://irep.iium.edu.my/74310/
http://irep.iium.edu.my/74310/
http://irep.iium.edu.my/74310/
http://irep.iium.edu.my/74310/3/74310%20ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITIES%20OF%20EXTRACTS.pdf
http://irep.iium.edu.my/74310/4/74310%20ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITIES%20OF%20EXTRACTS%20SCOPUS.pdf
id iium-74310
recordtype eprints
spelling iium-743102019-09-23T08:34:15Z http://irep.iium.edu.my/74310/ Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum Aminudin, Nurul Iman Ahmad, Farediah Bakhtiar, M. Taher QD Chemistry Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp because this genus is a rich source of active secondary metabolites which shows anti-HIV, cytotoxicity and antimicrobial properties. In this study, antibacterial and antioxidant activities of barks and leaves of C. ferrugineum and C. incrassatum were investigated. Cold extraction method employing dichloromethane, ethyl acetate and methanol as solvent was performed. All extracts were tested for their total phenolic content and antioxidant activities by DPPH radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. The methanol extract from the leaves of C. ferrugineum showed the highest TPC value at 122.08 mg GAE/g and the lowest DPPH SC50 value at 11.80 μg/mL. The methanol extract from the barks of C. ferrugineum was found to have the highest FRAP value among all extracts. The antibacterial activity of all extracts was tested using minimum inhibition concentration (MIC) test against Bacillus subtilis, Staphylococcus aureus, Escheria coli and Pseudomonas aeruginosa. Only the dichloromethane extract from bark of C. ferrugineum showed moderate MIC value against Gram positive bacteria, B. subtilis and S. aureus at 125 μg/mL. **************************************************************************** Calophyllum adalah genus pan-tropika di dalam keluarga Guttiferae dan dikenali secara tempatan di Malaysia sebagai ‘bintangor’. Terdapat minat berterusan untuk mengkaji lebih mendalam tentang fitokimia Calophyllum sp kerana genus ini adalah sumber yang kaya dengan metabolit sekunder aktif yang menunjukkan ciri-ciri anti-HIV, sitotoksiti dan antimikrob. Di dalam kajian ini, aktiviti antibakteria dan antioksidan kulit batang dan daun C. ferrugineum dan C. incrassatum telah dikaji. Kaedah pengekstrakan sejuk menggunakan diklorometana, etil asetat dan metanol sebagai pelarut telah dilakukan. Semua ekstrak telah diuji untuk kandungan total fenolik dan aktiviti antioksidan melalui cerakin pemerangkapan radikal DPPH dan kuasa antioksidan penurunan Ferik (FRAP). Ekstrak metanol daripada daun C. ferrugineum telah menunjukkan nilai TPC tertinggi pada 122.08 mg GAE/g dan nilai SC50 DPPH terendah pada 11.80 µg/mL. Ekstrak metanol daripada kulit batang C. ferrugineum telah menunjukkan nilai FRAP tertinggi antara semua ekstrak. Aktiviti antibakteria semua ekstrak telah diuji untuk kepekatan rencatan minimum (MIC) terhadap Bacillus subtilis, Staphylococcus aureus, Escheria coli dan Pseudomonas aeruginosa. Hanya ekstrak diklorometana kulit batang C. ferrugineum menunjukkan nilai MIC yang sederhana terhadap bakteria Gram positif, B. subtilis dan S. aureus pada 125 µg/mL. The Malaysian Analytical Sciences Society 2019-08 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74310/3/74310%20ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITIES%20OF%20EXTRACTS.pdf application/pdf en http://irep.iium.edu.my/74310/4/74310%20ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITIES%20OF%20EXTRACTS%20SCOPUS.pdf Aminudin, Nurul Iman and Ahmad, Farediah and Bakhtiar, M. Taher (2019) Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum. Malaysian Journal of Analytical Sciences, 23 (4). pp. 637-647. ISSN 1394-2506 http://www.ukm.my/mjas/v23_n4/pdf/Nurul_23_4_9.pdf 10.17576/mjas-2019-2304-09
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic QD Chemistry
spellingShingle QD Chemistry
Aminudin, Nurul Iman
Ahmad, Farediah
Bakhtiar, M. Taher
Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
description Calophyllum is a pan-tropical genus belongs to the Guttiferae family and locally known in Malaysia as ‘bintangor’. There has been a continual interest to further investigate the phytochemistry of Calophyllum sp because this genus is a rich source of active secondary metabolites which shows anti-HIV, cytotoxicity and antimicrobial properties. In this study, antibacterial and antioxidant activities of barks and leaves of C. ferrugineum and C. incrassatum were investigated. Cold extraction method employing dichloromethane, ethyl acetate and methanol as solvent was performed. All extracts were tested for their total phenolic content and antioxidant activities by DPPH radical scavenging and Ferric Reducing Antioxidant Power (FRAP) assays. The methanol extract from the leaves of C. ferrugineum showed the highest TPC value at 122.08 mg GAE/g and the lowest DPPH SC50 value at 11.80 μg/mL. The methanol extract from the barks of C. ferrugineum was found to have the highest FRAP value among all extracts. The antibacterial activity of all extracts was tested using minimum inhibition concentration (MIC) test against Bacillus subtilis, Staphylococcus aureus, Escheria coli and Pseudomonas aeruginosa. Only the dichloromethane extract from bark of C. ferrugineum showed moderate MIC value against Gram positive bacteria, B. subtilis and S. aureus at 125 μg/mL. **************************************************************************** Calophyllum adalah genus pan-tropika di dalam keluarga Guttiferae dan dikenali secara tempatan di Malaysia sebagai ‘bintangor’. Terdapat minat berterusan untuk mengkaji lebih mendalam tentang fitokimia Calophyllum sp kerana genus ini adalah sumber yang kaya dengan metabolit sekunder aktif yang menunjukkan ciri-ciri anti-HIV, sitotoksiti dan antimikrob. Di dalam kajian ini, aktiviti antibakteria dan antioksidan kulit batang dan daun C. ferrugineum dan C. incrassatum telah dikaji. Kaedah pengekstrakan sejuk menggunakan diklorometana, etil asetat dan metanol sebagai pelarut telah dilakukan. Semua ekstrak telah diuji untuk kandungan total fenolik dan aktiviti antioksidan melalui cerakin pemerangkapan radikal DPPH dan kuasa antioksidan penurunan Ferik (FRAP). Ekstrak metanol daripada daun C. ferrugineum telah menunjukkan nilai TPC tertinggi pada 122.08 mg GAE/g dan nilai SC50 DPPH terendah pada 11.80 µg/mL. Ekstrak metanol daripada kulit batang C. ferrugineum telah menunjukkan nilai FRAP tertinggi antara semua ekstrak. Aktiviti antibakteria semua ekstrak telah diuji untuk kepekatan rencatan minimum (MIC) terhadap Bacillus subtilis, Staphylococcus aureus, Escheria coli dan Pseudomonas aeruginosa. Hanya ekstrak diklorometana kulit batang C. ferrugineum menunjukkan nilai MIC yang sederhana terhadap bakteria Gram positif, B. subtilis dan S. aureus pada 125 µg/mL.
format Article
author Aminudin, Nurul Iman
Ahmad, Farediah
Bakhtiar, M. Taher
author_facet Aminudin, Nurul Iman
Ahmad, Farediah
Bakhtiar, M. Taher
author_sort Aminudin, Nurul Iman
title Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
title_short Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
title_full Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
title_fullStr Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
title_full_unstemmed Antibacterial and antioxidant activities of extracts from Calophyllum ferrugineum and Calophyllum incrassatum = Aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
title_sort antibacterial and antioxidant activities of extracts from calophyllum ferrugineum and calophyllum incrassatum = aktiviti antibakteria dan antioksidan terhadap ekstrak daripada calophyllum ferrugineum dan calophyllum incrassatum
publisher The Malaysian Analytical Sciences Society
publishDate 2019
url http://irep.iium.edu.my/74310/
http://irep.iium.edu.my/74310/
http://irep.iium.edu.my/74310/
http://irep.iium.edu.my/74310/3/74310%20ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITIES%20OF%20EXTRACTS.pdf
http://irep.iium.edu.my/74310/4/74310%20ANTIBACTERIAL%20AND%20ANTIOXIDANT%20ACTIVITIES%20OF%20EXTRACTS%20SCOPUS.pdf
first_indexed 2023-09-18T21:45:16Z
last_indexed 2023-09-18T21:45:16Z
_version_ 1777413407507480576

Similar Items