Factors associated with deep surgical site Infection following Spinal surgery: a pilot study

Introduction: Surgical site infection (SSI) is the most common healthcare-related infection in surgical patients. Patients who have undergone spinal surgeries and have contracted postoperative SSI face increased morbidity and mortality, which invariably leads to additional burden on the healthcare s...

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Main Authors:	Mor Japar Khan, Ed Simor Khan, Ren, Yi Kow, M. Arifin, Khairul Bariyyah, Komahen, Colin, Chooi, Leng Low, Bee, Chiu Lim
Format:	Article
Language:	English
Published:	Cureus, Inc. 2019
Subjects:	RD701 Orthopedics
Online Access:	http://irep.iium.edu.my/74104/ http://irep.iium.edu.my/74104/ http://irep.iium.edu.my/74104/ http://irep.iium.edu.my/74104/1/2019%20Factor%20associated%20with%20Deep%20surgical%20site%20infection%20following%20spinal%20injury.pdf

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spelling	iium-741042019-09-13T02:29:19Z http://irep.iium.edu.my/74104/ Factors associated with deep surgical site Infection following Spinal surgery: a pilot study Mor Japar Khan, Ed Simor Khan Ren, Yi Kow M. Arifin, Khairul Bariyyah Komahen, Colin Chooi, Leng Low Bee, Chiu Lim RD701 Orthopedics Introduction: Surgical site infection (SSI) is the most common healthcare-related infection in surgical patients. Patients who have undergone spinal surgeries and have contracted postoperative SSI face increased morbidity and mortality, which invariably leads to additional burden on the healthcare system and higher costs. The risk factors for the increase in SSI in patients who have undergone spinal surgery have been investigated in numerous studies but no studies have been performed in Malaysia. The aim of this pilot study is to determine the incidence and factors associated with deep SSIs in patients that have undergone spinal surgeries. Methods : This retrospective study includes all patients who underwent spinal surgeries at Tengku Ampuan Afzan Hospital, Kuantan, from 1 January 2016 to 31 December 2017. Patients with an active spinal infection, polytrauma, and open fractures were excluded from this study. Patient characteristics and laboratory investigations were extracted to determine the risk factors for deep SSI events. Associations between SSI and risk factors were analyzed with SPSS V21.0 (IBM, Armonk, NY). Results: The univariate analysis indicated that fracture dislocation at the thoraco-lumbar junction (p=0.008) and a history of preoperative blood product transfusion (p=0.003) were associated with deep SSI. Other factors such as age (p=0.162), gender (p=0.262), body mass index (p=0.215), smoking status (0.272), number of vertebrae involved in the surgery (p=0.837), spinal cord involvement (p=0.259), postoperative hemoglobin reduction (p=0.816), and preoperative white blood cell count (p=0.278) were not associated with deep SSI. Conclusions: This pilot study highlights the factors associated with deep SSI in spinal surgeries. A larger study is needed to further confirm these findings. Cureus, Inc. 2019-04-03 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74104/1/2019%20Factor%20associated%20with%20Deep%20surgical%20site%20infection%20following%20spinal%20injury.pdf Mor Japar Khan, Ed Simor Khan and Ren, Yi Kow and M. Arifin, Khairul Bariyyah and Komahen, Colin and Chooi, Leng Low and Bee, Chiu Lim (2019) Factors associated with deep surgical site Infection following Spinal surgery: a pilot study. Cureus, 11 (4). pp. 1-9. ISSN 2168-8184 https://assets.cureus.com/uploads/original_article/pdf/18021/1559840240-20190606-17849-6bnojr.pdf 10.7759/cureus.4377
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RD701 Orthopedics
spellingShingle	RD701 Orthopedics Mor Japar Khan, Ed Simor Khan Ren, Yi Kow M. Arifin, Khairul Bariyyah Komahen, Colin Chooi, Leng Low Bee, Chiu Lim Factors associated with deep surgical site Infection following Spinal surgery: a pilot study
description	Introduction: Surgical site infection (SSI) is the most common healthcare-related infection in surgical patients. Patients who have undergone spinal surgeries and have contracted postoperative SSI face increased morbidity and mortality, which invariably leads to additional burden on the healthcare system and higher costs. The risk factors for the increase in SSI in patients who have undergone spinal surgery have been investigated in numerous studies but no studies have been performed in Malaysia. The aim of this pilot study is to determine the incidence and factors associated with deep SSIs in patients that have undergone spinal surgeries. Methods : This retrospective study includes all patients who underwent spinal surgeries at Tengku Ampuan Afzan Hospital, Kuantan, from 1 January 2016 to 31 December 2017. Patients with an active spinal infection, polytrauma, and open fractures were excluded from this study. Patient characteristics and laboratory investigations were extracted to determine the risk factors for deep SSI events. Associations between SSI and risk factors were analyzed with SPSS V21.0 (IBM, Armonk, NY). Results: The univariate analysis indicated that fracture dislocation at the thoraco-lumbar junction (p=0.008) and a history of preoperative blood product transfusion (p=0.003) were associated with deep SSI. Other factors such as age (p=0.162), gender (p=0.262), body mass index (p=0.215), smoking status (0.272), number of vertebrae involved in the surgery (p=0.837), spinal cord involvement (p=0.259), postoperative hemoglobin reduction (p=0.816), and preoperative white blood cell count (p=0.278) were not associated with deep SSI. Conclusions: This pilot study highlights the factors associated with deep SSI in spinal surgeries. A larger study is needed to further confirm these findings.
format	Article
author	Mor Japar Khan, Ed Simor Khan Ren, Yi Kow M. Arifin, Khairul Bariyyah Komahen, Colin Chooi, Leng Low Bee, Chiu Lim
author_facet	Mor Japar Khan, Ed Simor Khan Ren, Yi Kow M. Arifin, Khairul Bariyyah Komahen, Colin Chooi, Leng Low Bee, Chiu Lim
author_sort	Mor Japar Khan, Ed Simor Khan
title	Factors associated with deep surgical site Infection following Spinal surgery: a pilot study
title_short	Factors associated with deep surgical site Infection following Spinal surgery: a pilot study
title_full	Factors associated with deep surgical site Infection following Spinal surgery: a pilot study
title_fullStr	Factors associated with deep surgical site Infection following Spinal surgery: a pilot study
title_full_unstemmed	Factors associated with deep surgical site Infection following Spinal surgery: a pilot study
title_sort	factors associated with deep surgical site infection following spinal surgery: a pilot study
publisher	Cureus, Inc.
publishDate	2019
url	http://irep.iium.edu.my/74104/ http://irep.iium.edu.my/74104/ http://irep.iium.edu.my/74104/ http://irep.iium.edu.my/74104/1/2019%20Factor%20associated%20with%20Deep%20surgical%20site%20infection%20following%20spinal%20injury.pdf
first_indexed	2023-09-18T21:44:59Z
last_indexed	2023-09-18T21:44:59Z
_version_	1777413389872529408

Factors associated with deep surgical site Infection following Spinal surgery: a pilot study

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