Psychosocial distress and blood pressure among young adults: role of cortisol as mediator

Introduction: Hypertension is the most prevalent risk factor of cardiovascular diseases in Malaysia. 17.3% of hypertension cases in Malaysia is attributed to adults aged 18 to 39 years. Psychosocial distress is a possible risk factor for elevated blood pressure in young adults, and cortisol could...

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Main Authors:	Wan Omar, Wan Fatein Nabeila, Mohd Shah, Azarisman Shah, Ab Rahman, Jamalludin, A.Talib, Norlelawati, Musa, Ramli, Mohd shah, Aida Nur Sharini, Aung, Sithu, Abdullah, Aszrin
Format:	Article
Language:	English English English
Published:	Kulliyyah of Medicine, International Islamic University Malaysia 2019
Subjects:	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
Online Access:	http://irep.iium.edu.my/74078/ http://irep.iium.edu.my/74078/ http://irep.iium.edu.my/74078/1/74078_Psychosocial%20distress%20and%20blood%20pressure%20among%20young%20adults.pdf http://irep.iium.edu.my/74078/2/74078_Psychosocial%20distress%20and%20blood%20pressure%20among%20young%20adults_SCOPUS.pdf http://irep.iium.edu.my/74078/13/74078_Psychosocial%20distress%20and%20blood%20pressure_WOS.pdf

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spelling	iium-740782020-03-19T04:23:28Z http://irep.iium.edu.my/74078/ Psychosocial distress and blood pressure among young adults: role of cortisol as mediator Wan Omar, Wan Fatein Nabeila Mohd Shah, Azarisman Shah Ab Rahman, Jamalludin A.Talib, Norlelawati Musa, Ramli Mohd shah, Aida Nur Sharini Aung, Sithu Abdullah, Aszrin RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System Introduction: Hypertension is the most prevalent risk factor of cardiovascular diseases in Malaysia. 17.3% of hypertension cases in Malaysia is attributed to adults aged 18 to 39 years. Psychosocial distress is a possible risk factor for elevated blood pressure in young adults, and cortisol could be the mediating factor. The aim of this study is to evaluate the mediating role of cortisol in hypertension and psychosocial distress in young adults. Methods and materials: A comparative cross-sectional study was conducted in 240 young adults aged 18 to 45 years. The body mass index, waist circumference and blood pressure parameters were recorded. Serum cortisol, creatinine, fasting blood glucose and lipid profile were measured following acute mental stress test. Psychosocial distress was assessed using the DASS-21 questionnaire. Results: Mean (standard deviation) values for SBP, DBP, MAP were 126.0(16.3), 84.1(12.2) and 98.1(13.1) mmHg respectively. Anxiety was significantly associated with systolic blood pressure (β=0.644), diastolic blood pressure (β=0.454) and mean arterial pressure (β=0.516) after adjusting for sex, age and cortisol. However, it was not mediated by cortisol. Depression and stress were not found to have any effect on blood pressure of the young adults studied. Conclusion: The data suggest that there is no elevated risk for psychosocial distress and hypertension that cortisol poses in young adults. Kulliyyah of Medicine, International Islamic University Malaysia 2019-08-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/74078/1/74078_Psychosocial%20distress%20and%20blood%20pressure%20among%20young%20adults.pdf application/pdf en http://irep.iium.edu.my/74078/2/74078_Psychosocial%20distress%20and%20blood%20pressure%20among%20young%20adults_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/74078/13/74078_Psychosocial%20distress%20and%20blood%20pressure_WOS.pdf Wan Omar, Wan Fatein Nabeila and Mohd Shah, Azarisman Shah and Ab Rahman, Jamalludin and A.Talib, Norlelawati and Musa, Ramli and Mohd shah, Aida Nur Sharini and Aung, Sithu and Abdullah, Aszrin (2019) Psychosocial distress and blood pressure among young adults: role of cortisol as mediator. International Medical Journal Malaysia, 18 (2). pp. 69-75. ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/volume_18_no_2/Pages-from-IMJMVol18No2-12.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System
spellingShingle	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry RC667 Specialties of Internal Medicine-Diseases of Circulatory (Cardiovascular) System Wan Omar, Wan Fatein Nabeila Mohd Shah, Azarisman Shah Ab Rahman, Jamalludin A.Talib, Norlelawati Musa, Ramli Mohd shah, Aida Nur Sharini Aung, Sithu Abdullah, Aszrin Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
description	Introduction: Hypertension is the most prevalent risk factor of cardiovascular diseases in Malaysia. 17.3% of hypertension cases in Malaysia is attributed to adults aged 18 to 39 years. Psychosocial distress is a possible risk factor for elevated blood pressure in young adults, and cortisol could be the mediating factor. The aim of this study is to evaluate the mediating role of cortisol in hypertension and psychosocial distress in young adults. Methods and materials: A comparative cross-sectional study was conducted in 240 young adults aged 18 to 45 years. The body mass index, waist circumference and blood pressure parameters were recorded. Serum cortisol, creatinine, fasting blood glucose and lipid profile were measured following acute mental stress test. Psychosocial distress was assessed using the DASS-21 questionnaire. Results: Mean (standard deviation) values for SBP, DBP, MAP were 126.0(16.3), 84.1(12.2) and 98.1(13.1) mmHg respectively. Anxiety was significantly associated with systolic blood pressure (β=0.644), diastolic blood pressure (β=0.454) and mean arterial pressure (β=0.516) after adjusting for sex, age and cortisol. However, it was not mediated by cortisol. Depression and stress were not found to have any effect on blood pressure of the young adults studied. Conclusion: The data suggest that there is no elevated risk for psychosocial distress and hypertension that cortisol poses in young adults.
format	Article
author	Wan Omar, Wan Fatein Nabeila Mohd Shah, Azarisman Shah Ab Rahman, Jamalludin A.Talib, Norlelawati Musa, Ramli Mohd shah, Aida Nur Sharini Aung, Sithu Abdullah, Aszrin
author_facet	Wan Omar, Wan Fatein Nabeila Mohd Shah, Azarisman Shah Ab Rahman, Jamalludin A.Talib, Norlelawati Musa, Ramli Mohd shah, Aida Nur Sharini Aung, Sithu Abdullah, Aszrin
author_sort	Wan Omar, Wan Fatein Nabeila
title	Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
title_short	Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
title_full	Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
title_fullStr	Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
title_full_unstemmed	Psychosocial distress and blood pressure among young adults: role of cortisol as mediator
title_sort	psychosocial distress and blood pressure among young adults: role of cortisol as mediator
publisher	Kulliyyah of Medicine, International Islamic University Malaysia
publishDate	2019
url	http://irep.iium.edu.my/74078/ http://irep.iium.edu.my/74078/ http://irep.iium.edu.my/74078/1/74078_Psychosocial%20distress%20and%20blood%20pressure%20among%20young%20adults.pdf http://irep.iium.edu.my/74078/2/74078_Psychosocial%20distress%20and%20blood%20pressure%20among%20young%20adults_SCOPUS.pdf http://irep.iium.edu.my/74078/13/74078_Psychosocial%20distress%20and%20blood%20pressure_WOS.pdf
first_indexed	2023-09-18T21:44:57Z
last_indexed	2023-09-18T21:44:57Z
_version_	1777413387672616960

Psychosocial distress and blood pressure among young adults: role of cortisol as mediator

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