Inflammatory response of bioscaffolds decellularized by sonication treatment

Decellularization of sonication system efficiency is dictated by evaluation of host immune response on scaffolds. This aim of this study is to examine the inflammatory response after implantation of bioscaffolds decellularized by sonication treatment at 35 days postsurgery in rats. In this study,...

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Main Authors:	Hazwani, Aqilah, Sha'ban, Munirah, Azhim, Azran
Format:	Conference or Workshop Item
Language:	English English
Published:	Springer 2018
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/72879/ http://irep.iium.edu.my/72879/ http://irep.iium.edu.my/72879/ http://irep.iium.edu.my/72879/14/72879%20Inflammatory%20Response.pdf http://irep.iium.edu.my/72879/2/72879%20Inflammatory%20Response%20of%20Bioscaffolds%20Decellularized%20SCOPUS.pdf

id	iium-72879
recordtype	eprints
spelling	iium-728792019-07-03T07:32:42Z http://irep.iium.edu.my/72879/ Inflammatory response of bioscaffolds decellularized by sonication treatment Hazwani, Aqilah Sha'ban, Munirah Azhim, Azran R Medicine (General) Decellularization of sonication system efficiency is dictated by evaluation of host immune response on scaffolds. This aim of this study is to examine the inflammatory response after implantation of bioscaffolds decellularized by sonication treatment at 35 days postsurgery in rats. In this study, aortic tissues decellularized by sonication treatment in 0.1 and 2% of Sodium Dodecyl Sulfate (SDS) detergents. Samples were washed for 5 days in Phosphate Buffer Saline (PBS) following decellularization. Samples were implanted in on the lower right thoracic cavity of rats for 35 days. To examine the inflammatory response, the implanted samples were explanted and evaluated histologically by Hematoxylin Eosin (H-E) staining. From the histological analysis, bioscaffolds decellularized by sonication treatment in response to macrophages shows the minimal inflammatory response. Minimal inflammatory response elicits by bioscaffolds suggests the safety of bioscaffolds prepared by sonication treatment as biomedical implants. Springer 2018 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/72879/14/72879%20Inflammatory%20Response.pdf application/pdf en http://irep.iium.edu.my/72879/2/72879%20Inflammatory%20Response%20of%20Bioscaffolds%20Decellularized%20SCOPUS.pdf Hazwani, Aqilah and Sha'ban, Munirah and Azhim, Azran (2018) Inflammatory response of bioscaffolds decellularized by sonication treatment. In: 2nd International Conference for Innovation in Biomedical Engineering and Life Sciences ICIBEL 2017 (in conjunction with APCMBE 2017), 10th–13th December 2017, Penang, Malaysia. https://link.springer.com/chapter/10.1007/978-981-10-7554-4_32 10.1007/978-981-10-7554-4_32
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Hazwani, Aqilah Sha'ban, Munirah Azhim, Azran Inflammatory response of bioscaffolds decellularized by sonication treatment
description	Decellularization of sonication system efficiency is dictated by evaluation of host immune response on scaffolds. This aim of this study is to examine the inflammatory response after implantation of bioscaffolds decellularized by sonication treatment at 35 days postsurgery in rats. In this study, aortic tissues decellularized by sonication treatment in 0.1 and 2% of Sodium Dodecyl Sulfate (SDS) detergents. Samples were washed for 5 days in Phosphate Buffer Saline (PBS) following decellularization. Samples were implanted in on the lower right thoracic cavity of rats for 35 days. To examine the inflammatory response, the implanted samples were explanted and evaluated histologically by Hematoxylin Eosin (H-E) staining. From the histological analysis, bioscaffolds decellularized by sonication treatment in response to macrophages shows the minimal inflammatory response. Minimal inflammatory response elicits by bioscaffolds suggests the safety of bioscaffolds prepared by sonication treatment as biomedical implants.
format	Conference or Workshop Item
author	Hazwani, Aqilah Sha'ban, Munirah Azhim, Azran
author_facet	Hazwani, Aqilah Sha'ban, Munirah Azhim, Azran
author_sort	Hazwani, Aqilah
title	Inflammatory response of bioscaffolds decellularized by sonication treatment
title_short	Inflammatory response of bioscaffolds decellularized by sonication treatment
title_full	Inflammatory response of bioscaffolds decellularized by sonication treatment
title_fullStr	Inflammatory response of bioscaffolds decellularized by sonication treatment
title_full_unstemmed	Inflammatory response of bioscaffolds decellularized by sonication treatment
title_sort	inflammatory response of bioscaffolds decellularized by sonication treatment
publisher	Springer
publishDate	2018
url	http://irep.iium.edu.my/72879/ http://irep.iium.edu.my/72879/ http://irep.iium.edu.my/72879/ http://irep.iium.edu.my/72879/14/72879%20Inflammatory%20Response.pdf http://irep.iium.edu.my/72879/2/72879%20Inflammatory%20Response%20of%20Bioscaffolds%20Decellularized%20SCOPUS.pdf
first_indexed	2023-09-18T21:43:20Z
last_indexed	2023-09-18T21:43:20Z
_version_	1777413285704892416

Inflammatory response of bioscaffolds decellularized by sonication treatment

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