Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults

Introduction: Obese adults have increased risk of developing cardiovascular diseases (CVD), which can be estimated using Framingham risk score (FRS). Identifying the risk of developing CVD may reiterate the necessity of intensive intervention to reduce the ever-increasing burden of this disease. How...

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Main Authors: Shahadan, Siti Zuhaidah, Daud, Azlina, Ibrahim, Muhammad, Md Isa, Muhammad Lokman, Draman, Samsul
Format: Conference or Workshop Item
Language:English
English
Published: 2016
Subjects:
Online Access:http://irep.iium.edu.my/72726/
http://irep.iium.edu.my/72726/1/SITI%20ZUHAIDAH%20SHAHADAN-ABSTRACT%20FOR%202ND%20INTERNATIONAL%20NURSING%20CONFERENCE%202016.pdf
http://irep.iium.edu.my/72726/8/Scan_20191227%20%284%29.pdf
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spelling iium-727262020-02-04T07:33:58Z http://irep.iium.edu.my/72726/ Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults Shahadan, Siti Zuhaidah Daud, Azlina Ibrahim, Muhammad Md Isa, Muhammad Lokman Draman, Samsul RT Nursing Introduction: Obese adults have increased risk of developing cardiovascular diseases (CVD), which can be estimated using Framingham risk score (FRS). Identifying the risk of developing CVD may reiterate the necessity of intensive intervention to reduce the ever-increasing burden of this disease. However, national data of FRS and its relationship with cardiometabolic risk (CMR) profile among Malaysian obese adults are insufficient. Objectives: The study was aimed to determine the prevalence of CMR profile and its relationship with FRS in Malaysian obese adults. Methods: A total of seventy one obese adults from Kuantan community (body mass index (BMI) ranged between 27.5 kg/m2 to 40 kg/m2 and age ranged between 20 to 62 years) were selected. Assessment of BMI, waist circumference (WC), blood pressure (BP), lipid profile and fasting blood glucose (FBG) were conducted. FRS was calculated using the online CVD risk calculator from National Institutes of Health (NIH) website. The variables used to estimate the risk were age, gender, BMI, systolic BP, smoking status, total cholesterol and high density lipoprotein (HDL), and hypertensive treatment. Results: For CMR abnormalities, the results show that WC (cm) and total cholesterol level (mmol/L) were elevated in both genders (WC: male; 101.78±8.63, female; 93.86±6.92, and total cholesterol: male; 5.63±0.73, female; 5.28±0.92). All participants in this study have low risk of developing CVD in the next 10 years (<10%) based on the FRS points. Male have higher FRS points as compared to female (p<0.05, CI 95% 0.31 to 3.17). Pearson correlation shows a moderate strength, positive linear relationship between FRS points and FBG level in both genders (male; r=.492, p=.003, n=20, female; r=.545, p<0.001, n=51). Discussion: Our result showed that obesity induced impaired fasting glucose was a significant factor in developing CVD among obese adults with elevated WC and total cholesterol level. It proves the theory that expanded adipose tissue in obese adults has increased blood glucose concentration. Conclusion: The present findings showed that Malaysian obese class I and II adults have elevated WC and total cholesterol level, and FBG was significantly correlated with FRS. 2016 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/72726/1/SITI%20ZUHAIDAH%20SHAHADAN-ABSTRACT%20FOR%202ND%20INTERNATIONAL%20NURSING%20CONFERENCE%202016.pdf application/pdf en http://irep.iium.edu.my/72726/8/Scan_20191227%20%284%29.pdf Shahadan, Siti Zuhaidah and Daud, Azlina and Ibrahim, Muhammad and Md Isa, Muhammad Lokman and Draman, Samsul (2016) Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults. In: 2nd International Nursing Conference, 6-7 October 2016, Kota Kinabalu, Sabah. (Unpublished)
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RT Nursing
spellingShingle RT Nursing
Shahadan, Siti Zuhaidah
Daud, Azlina
Ibrahim, Muhammad
Md Isa, Muhammad Lokman
Draman, Samsul
Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults
description Introduction: Obese adults have increased risk of developing cardiovascular diseases (CVD), which can be estimated using Framingham risk score (FRS). Identifying the risk of developing CVD may reiterate the necessity of intensive intervention to reduce the ever-increasing burden of this disease. However, national data of FRS and its relationship with cardiometabolic risk (CMR) profile among Malaysian obese adults are insufficient. Objectives: The study was aimed to determine the prevalence of CMR profile and its relationship with FRS in Malaysian obese adults. Methods: A total of seventy one obese adults from Kuantan community (body mass index (BMI) ranged between 27.5 kg/m2 to 40 kg/m2 and age ranged between 20 to 62 years) were selected. Assessment of BMI, waist circumference (WC), blood pressure (BP), lipid profile and fasting blood glucose (FBG) were conducted. FRS was calculated using the online CVD risk calculator from National Institutes of Health (NIH) website. The variables used to estimate the risk were age, gender, BMI, systolic BP, smoking status, total cholesterol and high density lipoprotein (HDL), and hypertensive treatment. Results: For CMR abnormalities, the results show that WC (cm) and total cholesterol level (mmol/L) were elevated in both genders (WC: male; 101.78±8.63, female; 93.86±6.92, and total cholesterol: male; 5.63±0.73, female; 5.28±0.92). All participants in this study have low risk of developing CVD in the next 10 years (<10%) based on the FRS points. Male have higher FRS points as compared to female (p<0.05, CI 95% 0.31 to 3.17). Pearson correlation shows a moderate strength, positive linear relationship between FRS points and FBG level in both genders (male; r=.492, p=.003, n=20, female; r=.545, p<0.001, n=51). Discussion: Our result showed that obesity induced impaired fasting glucose was a significant factor in developing CVD among obese adults with elevated WC and total cholesterol level. It proves the theory that expanded adipose tissue in obese adults has increased blood glucose concentration. Conclusion: The present findings showed that Malaysian obese class I and II adults have elevated WC and total cholesterol level, and FBG was significantly correlated with FRS.
format Conference or Workshop Item
author Shahadan, Siti Zuhaidah
Daud, Azlina
Ibrahim, Muhammad
Md Isa, Muhammad Lokman
Draman, Samsul
author_facet Shahadan, Siti Zuhaidah
Daud, Azlina
Ibrahim, Muhammad
Md Isa, Muhammad Lokman
Draman, Samsul
author_sort Shahadan, Siti Zuhaidah
title Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults
title_short Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults
title_full Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults
title_fullStr Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults
title_full_unstemmed Correlation between framingham risk score and cardiometabolic risk profile in Malaysian obese adults
title_sort correlation between framingham risk score and cardiometabolic risk profile in malaysian obese adults
publishDate 2016
url http://irep.iium.edu.my/72726/
http://irep.iium.edu.my/72726/1/SITI%20ZUHAIDAH%20SHAHADAN-ABSTRACT%20FOR%202ND%20INTERNATIONAL%20NURSING%20CONFERENCE%202016.pdf
http://irep.iium.edu.my/72726/8/Scan_20191227%20%284%29.pdf
first_indexed 2023-09-18T21:43:05Z
last_indexed 2023-09-18T21:43:05Z
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