Corneo-pterygium total area measurements utilising image analysis method

Purpose: To describe an objective method to accurately quantify corneo-pterygium total area (CPTA) by utilising image analysis method and to evaluate its association with corneal astigma- tism (CA). Methods: 120 primary pterygium participants were selected from patients who visited an oph- thalmolo...

Full description

Bibliographic Details
Main Authors:	Hilmi, Mohd Radzi, Mohd. Kamal, Khairidzan, Che Azemin, Mohd Zulfaezal, Ariffin, Azrin Esmady
Format:	Article
Language:	English English
Published:	Elsevier 2019
Subjects:	RE Ophthalmology
Online Access:	http://irep.iium.edu.my/72277/ http://irep.iium.edu.my/72277/ http://irep.iium.edu.my/72277/ http://irep.iium.edu.my/72277/1/72277_Corneo-pterygium%20total%20area%20measurements_article.pdf http://irep.iium.edu.my/72277/2/72277_Corneo-pterygium%20total%20area%20measurements_scopus.pdf

id	iium-72277
recordtype	eprints
spelling	iium-722772019-11-26T09:34:28Z http://irep.iium.edu.my/72277/ Corneo-pterygium total area measurements utilising image analysis method Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady RE Ophthalmology Purpose: To describe an objective method to accurately quantify corneo-pterygium total area (CPTA) by utilising image analysis method and to evaluate its association with corneal astigma- tism (CA). Methods: 120 primary pterygium participants were selected from patients who visited an oph- thalmology clinic. We adopted image analysis software in calculating the size of invading pterygium to the cornea. The marking of the calculated area was done manually, and the total area size was measured in pixel. The computed area is defined as the area from the apex of pterygium to the limbal-corneal border. Then, from the pixel, it was transformed into a per- centage (%), which represents the CPTA relative to the entire corneal surface area. Intra- and inter-observer reliability testing were performed by repeating the tracing process twice with a different sequence of images at least one (1) month apart. Intraclass correlation (ICC) and scatter plot were used to describe the reliability of measurement. Results: The overall mean (N = 120) of CPTA was 45.26 ± 13.51% (CI: 42.38-48.36). Reliability for region of interest (ROI) demarcation of CPTA were excellent with intra and inter-agreement of 0.995 (95% CI, 0.994-0.998; P < 0.001) and 0.994 (95% CI, 0.992-0.997; P < 0.001) respectively. The new method was positively associated with corneal astigmatism (P < 0.01). This method was able to predict 37% of the variance in CA compared to 21% using standard method. Conclusions: Image analysis method is useful, reliable and practical in the clinical setting to objectively quantify actual pterygium size, shapes and its effects on the anterior corneal curvature. Elsevier 2019-05-13 Article PeerReviewed application/pdf en http://irep.iium.edu.my/72277/1/72277_Corneo-pterygium%20total%20area%20measurements_article.pdf application/pdf en http://irep.iium.edu.my/72277/2/72277_Corneo-pterygium%20total%20area%20measurements_scopus.pdf Hilmi, Mohd Radzi and Mohd. Kamal, Khairidzan and Che Azemin, Mohd Zulfaezal and Ariffin, Azrin Esmady (2019) Corneo-pterygium total area measurements utilising image analysis method. Journal of Optometry, 12 (4). pp. 272-277. ISSN 1888-4296 E-ISSN 1989-1342 https://www.sciencedirect.com/science/article/pii/S188842961930024X 10.1016/j.optom.2019.04.001
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RE Ophthalmology
spellingShingle	RE Ophthalmology Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady Corneo-pterygium total area measurements utilising image analysis method
description	Purpose: To describe an objective method to accurately quantify corneo-pterygium total area (CPTA) by utilising image analysis method and to evaluate its association with corneal astigma- tism (CA). Methods: 120 primary pterygium participants were selected from patients who visited an oph- thalmology clinic. We adopted image analysis software in calculating the size of invading pterygium to the cornea. The marking of the calculated area was done manually, and the total area size was measured in pixel. The computed area is defined as the area from the apex of pterygium to the limbal-corneal border. Then, from the pixel, it was transformed into a per- centage (%), which represents the CPTA relative to the entire corneal surface area. Intra- and inter-observer reliability testing were performed by repeating the tracing process twice with a different sequence of images at least one (1) month apart. Intraclass correlation (ICC) and scatter plot were used to describe the reliability of measurement. Results: The overall mean (N = 120) of CPTA was 45.26 ± 13.51% (CI: 42.38-48.36). Reliability for region of interest (ROI) demarcation of CPTA were excellent with intra and inter-agreement of 0.995 (95% CI, 0.994-0.998; P < 0.001) and 0.994 (95% CI, 0.992-0.997; P < 0.001) respectively. The new method was positively associated with corneal astigmatism (P < 0.01). This method was able to predict 37% of the variance in CA compared to 21% using standard method. Conclusions: Image analysis method is useful, reliable and practical in the clinical setting to objectively quantify actual pterygium size, shapes and its effects on the anterior corneal curvature.
format	Article
author	Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady
author_facet	Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady
author_sort	Hilmi, Mohd Radzi
title	Corneo-pterygium total area measurements utilising image analysis method
title_short	Corneo-pterygium total area measurements utilising image analysis method
title_full	Corneo-pterygium total area measurements utilising image analysis method
title_fullStr	Corneo-pterygium total area measurements utilising image analysis method
title_full_unstemmed	Corneo-pterygium total area measurements utilising image analysis method
title_sort	corneo-pterygium total area measurements utilising image analysis method
publisher	Elsevier
publishDate	2019
url	http://irep.iium.edu.my/72277/ http://irep.iium.edu.my/72277/ http://irep.iium.edu.my/72277/ http://irep.iium.edu.my/72277/1/72277_Corneo-pterygium%20total%20area%20measurements_article.pdf http://irep.iium.edu.my/72277/2/72277_Corneo-pterygium%20total%20area%20measurements_scopus.pdf
first_indexed	2023-09-18T21:42:24Z
last_indexed	2023-09-18T21:42:24Z
_version_	1777413227088445440

Corneo-pterygium total area measurements utilising image analysis method

Similar Items