The use of cell culture technique in small molecule antidiabetes drug discovery

Type 2 diabetes is a metabolic disorder characterized by insulin resistance caused by multifactorial etiology including environmental factors particularly diet and genetic components. According to International Diabetes Federation in 2017, approximately 425 million adults were suffering with diabete...

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Main Author:	Bakhtiar, M. Taher
Format:	Conference or Workshop Item
Language:	English
Published:	2019
Subjects:	RS192 Materia Medica-Pharmaceutical Technology
Online Access:	http://irep.iium.edu.my/72010/ http://irep.iium.edu.my/72010/ http://irep.iium.edu.my/72010/1/BSBMB%20Conf%202019.pdf

id	iium-72010
recordtype	eprints
spelling	iium-720102019-05-08T02:37:08Z http://irep.iium.edu.my/72010/ The use of cell culture technique in small molecule antidiabetes drug discovery Bakhtiar, M. Taher RS192 Materia Medica-Pharmaceutical Technology Type 2 diabetes is a metabolic disorder characterized by insulin resistance caused by multifactorial etiology including environmental factors particularly diet and genetic components. According to International Diabetes Federation in 2017, approximately 425 million adults were suffering with diabetes and it will increase to 629 million in 2045. As part of UN Sustainable Development Goal on Good Health and Well-being, research initiative on the exploration of potential antidiabetes agent from nature has been conducted extensively. Cell culture has been developed as an important tool in antidiabetes drug discovery. The cell culture technique is considered as the most reliable technique to minimize the use of animal in diabetes experimental works under 3R (reduction, replacement and refinement) rules. Recently, most research on diabetes has focused on adipocyte, which is used as a model for testing of adipocyte differentiation, glucose uptake, glucose transport and insulin sensitivity of novel antidiabetes drugs. Numbers of plants and compound have been evaluated for their antidiabetes effects on 3T3-L1 adipocytes cells. It was found that some extracts and compound exhibited interesting antidiabetes properties. 2019 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/72010/1/BSBMB%20Conf%202019.pdf Bakhtiar, M. Taher (2019) The use of cell culture technique in small molecule antidiabetes drug discovery. In: BSBMB Conference 2019, 27th-28th April 2019, Chittagong, Bangladesh. (Unpublished) http://www.bdsbmb.org/upcoming.htm
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS192 Materia Medica-Pharmaceutical Technology
spellingShingle	RS192 Materia Medica-Pharmaceutical Technology Bakhtiar, M. Taher The use of cell culture technique in small molecule antidiabetes drug discovery
description	Type 2 diabetes is a metabolic disorder characterized by insulin resistance caused by multifactorial etiology including environmental factors particularly diet and genetic components. According to International Diabetes Federation in 2017, approximately 425 million adults were suffering with diabetes and it will increase to 629 million in 2045. As part of UN Sustainable Development Goal on Good Health and Well-being, research initiative on the exploration of potential antidiabetes agent from nature has been conducted extensively. Cell culture has been developed as an important tool in antidiabetes drug discovery. The cell culture technique is considered as the most reliable technique to minimize the use of animal in diabetes experimental works under 3R (reduction, replacement and refinement) rules. Recently, most research on diabetes has focused on adipocyte, which is used as a model for testing of adipocyte differentiation, glucose uptake, glucose transport and insulin sensitivity of novel antidiabetes drugs. Numbers of plants and compound have been evaluated for their antidiabetes effects on 3T3-L1 adipocytes cells. It was found that some extracts and compound exhibited interesting antidiabetes properties.
format	Conference or Workshop Item
author	Bakhtiar, M. Taher
author_facet	Bakhtiar, M. Taher
author_sort	Bakhtiar, M. Taher
title	The use of cell culture technique in small molecule antidiabetes drug discovery
title_short	The use of cell culture technique in small molecule antidiabetes drug discovery
title_full	The use of cell culture technique in small molecule antidiabetes drug discovery
title_fullStr	The use of cell culture technique in small molecule antidiabetes drug discovery
title_full_unstemmed	The use of cell culture technique in small molecule antidiabetes drug discovery
title_sort	use of cell culture technique in small molecule antidiabetes drug discovery
publishDate	2019
url	http://irep.iium.edu.my/72010/ http://irep.iium.edu.my/72010/ http://irep.iium.edu.my/72010/1/BSBMB%20Conf%202019.pdf
first_indexed	2023-09-18T21:42:06Z
last_indexed	2023-09-18T21:42:06Z
_version_	1777413208828542976

The use of cell culture technique in small molecule antidiabetes drug discovery

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