Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness

Introduction: A significant degree of corneal astigmatism can be induced by the encroachment of a pterygium onto a cornea. As various pterygium morphologies have been advocated as contributing factor on corneal astigmatism, little support in the literature available in establishing techniques in me...

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Main Authors:	Hilmi, Mohd Radzi, Mohd. Kamal, Khairidzan, Che Azemin, Mohd Zulfaezal, Ariffin, Azrin Esmady
Format:	Article
Language:	English English
Published:	Medical Faculty of Sultan Agong Islamic University 2019
Subjects:	RE Ophthalmology
Online Access:	http://irep.iium.edu.my/71535/ http://irep.iium.edu.my/71535/ http://irep.iium.edu.my/71535/1/Utilization%20of%20anterior%20segment%20optical%20coherence%20tomography%20enhanced%20high%20resolution%20corneal%20in%20measuring%20pterygium%20thickness.pdf http://irep.iium.edu.my/71535/7/Editor_Author%20Correspondence.pdf

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recordtype	eprints
spelling	iium-715352019-04-12T08:10:21Z http://irep.iium.edu.my/71535/ Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady RE Ophthalmology Introduction: A significant degree of corneal astigmatism can be induced by the encroachment of a pterygium onto a cornea. As various pterygium morphologies have been advocated as contributing factor on corneal astigmatism, little support in the literature available in establishing techniques in measuring pterygium thickness as clinical indicator. To further substantiate claims of establishing measurement of pterygium thickness, the aim of this study was to describe a quantitative method in determining pterygium thickness using anterior segment optical coherence tomography. Methods: Anterior segment imaging was performed using enhanced high resolution cornea of Visante™ optical coherence tomography in 120 primary pterygium eyes. Prior to imaging, corneal topography assessment was performed on each pterygium eye in order to identify its topographic location. Based on topography mapping, three meridians (in degrees) were selected as close as possible to the pterygium border, which signify the demarcation of pterygium from the cornea. Reliability testing between intra and inter-observer of optical coherence tomography imaging modality was examined using intraclass correlation and scatter plot. Results: The overall (n = 120) mean and standard deviation of pterygium thickness via enhanced high resolution cornea of optical coherence tomography modality were 0.48 ± 0.10 mm (confidence interval: 0.45 – 0.50). Optical coherence tomography imaging also showed excellent intra and intergrader reliability in measuring pterygium thickness with intraclass correlation of 0.997 (confidence interval: 0.994 – 0.998). Conclusions: Enhanced high resolution cornea of anterior segment optical coherence tomography imaging is a better choice in assessing pterygium compared to traditional slit-lamp biomicroscopy. This tool is applicable for future work related to better understanding on the role thickness in pterygium morphology, its progression and prediction of induced corneal astigmatism and visual impairment due to pterygium. Medical Faculty of Sultan Agong Islamic University 2019-07-24 Article PeerReviewed application/pdf en http://irep.iium.edu.my/71535/1/Utilization%20of%20anterior%20segment%20optical%20coherence%20tomography%20enhanced%20high%20resolution%20corneal%20in%20measuring%20pterygium%20thickness.pdf application/pdf en http://irep.iium.edu.my/71535/7/Editor_Author%20Correspondence.pdf Hilmi, Mohd Radzi and Mohd. Kamal, Khairidzan and Che Azemin, Mohd Zulfaezal and Ariffin, Azrin Esmady (2019) Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness. Journal of Medicine and Health (Sains medika), xx (xx). pp. 1-13. ISSN 2085-1545 E-ISSN 2339-093X (In Press) http://jurnal.unissula.ac.id/index.php/sainsmedika/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RE Ophthalmology
spellingShingle	RE Ophthalmology Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
description	Introduction: A significant degree of corneal astigmatism can be induced by the encroachment of a pterygium onto a cornea. As various pterygium morphologies have been advocated as contributing factor on corneal astigmatism, little support in the literature available in establishing techniques in measuring pterygium thickness as clinical indicator. To further substantiate claims of establishing measurement of pterygium thickness, the aim of this study was to describe a quantitative method in determining pterygium thickness using anterior segment optical coherence tomography. Methods: Anterior segment imaging was performed using enhanced high resolution cornea of Visante™ optical coherence tomography in 120 primary pterygium eyes. Prior to imaging, corneal topography assessment was performed on each pterygium eye in order to identify its topographic location. Based on topography mapping, three meridians (in degrees) were selected as close as possible to the pterygium border, which signify the demarcation of pterygium from the cornea. Reliability testing between intra and inter-observer of optical coherence tomography imaging modality was examined using intraclass correlation and scatter plot. Results: The overall (n = 120) mean and standard deviation of pterygium thickness via enhanced high resolution cornea of optical coherence tomography modality were 0.48 ± 0.10 mm (confidence interval: 0.45 – 0.50). Optical coherence tomography imaging also showed excellent intra and intergrader reliability in measuring pterygium thickness with intraclass correlation of 0.997 (confidence interval: 0.994 – 0.998). Conclusions: Enhanced high resolution cornea of anterior segment optical coherence tomography imaging is a better choice in assessing pterygium compared to traditional slit-lamp biomicroscopy. This tool is applicable for future work related to better understanding on the role thickness in pterygium morphology, its progression and prediction of induced corneal astigmatism and visual impairment due to pterygium.
format	Article
author	Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady
author_facet	Hilmi, Mohd Radzi Mohd. Kamal, Khairidzan Che Azemin, Mohd Zulfaezal Ariffin, Azrin Esmady
author_sort	Hilmi, Mohd Radzi
title	Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
title_short	Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
title_full	Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
title_fullStr	Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
title_full_unstemmed	Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
title_sort	utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness
publisher	Medical Faculty of Sultan Agong Islamic University
publishDate	2019
url	http://irep.iium.edu.my/71535/ http://irep.iium.edu.my/71535/ http://irep.iium.edu.my/71535/1/Utilization%20of%20anterior%20segment%20optical%20coherence%20tomography%20enhanced%20high%20resolution%20corneal%20in%20measuring%20pterygium%20thickness.pdf http://irep.iium.edu.my/71535/7/Editor_Author%20Correspondence.pdf
first_indexed	2023-09-18T21:41:26Z
last_indexed	2023-09-18T21:41:26Z
_version_	1777413166455586816

Utilization of anterior segment optical coherence tomography enhanced high resolution corneal in measuring pterygium thickness

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