Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves

Herbal plants are rich sources of secondary metabolites such as phenolics which can be beneficial to improve human health. Previous studies reported that phenolic compounds could lower the risk of heart diseases, occurrence of cancers as well as microbial infections. Piper sarmentosum or locally kn...

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Main Authors:	Mustafa, Farah Farisha, Ibrahim, Maizatul Akma, Mohamad, Habsah
Format:	Conference or Workshop Item
Language:	English
Published:	2017
Subjects:	Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology
Online Access:	http://irep.iium.edu.my/71451/ http://irep.iium.edu.my/71451/7/71451%20programme.pdf

id	iium-71451
recordtype	eprints
spelling	iium-714512019-05-07T06:38:30Z http://irep.iium.edu.my/71451/ Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves Mustafa, Farah Farisha Ibrahim, Maizatul Akma Mohamad, Habsah Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology Herbal plants are rich sources of secondary metabolites such as phenolics which can be beneficial to improve human health. Previous studies reported that phenolic compounds could lower the risk of heart diseases, occurrence of cancers as well as microbial infections. Piper sarmentosum or locally known as Kaduk is a tropical herb plant that is well established for many traditional medicinal purposes. These benefits may depend significantly on the phenolic content. Hence, the identification of phenolic compounds in this plant is necessary. The objective of the present study was to identify the phenolic compounds in crude methanolic extract of Piper sarmentosum leaves. Total phenolic content was determined spectrometrically according to Folin-Ciocalteu procedures. The characterization of the phenolic compounds was examined using reverse phase HPLC and GC-MS analyses. The total phenolic content was found to be 142.72 mg[GAE]/g of the Kaduk leaves extract. The presences of gallic acid, tannic acid, quercetin and naringenin were identified from the RP-HPLC analysis. From GC-MS analysis, the presences of elemicine, myristicine, methyleugenol and hydrocinnamic acid were revealed. Our findings provided the evidence that crude methanolic extract of Piper sarmentosum leaves contains high content of active phenolic compounds that might have the potential to be incorporated as the basis ingredient in medicines to treat various diseases in Malaysia. 2017 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/71451/7/71451%20programme.pdf Mustafa, Farah Farisha and Ibrahim, Maizatul Akma and Mohamad, Habsah (2017) Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves. In: 6th International Conference on Advancement in Science and Technology (iCAST 2017), 9th August 2017, Kuantan, Pahang. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology
spellingShingle	Q Science (General) QK Botany QR Microbiology RM Therapeutics. Pharmacology Mustafa, Farah Farisha Ibrahim, Maizatul Akma Mohamad, Habsah Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves
description	Herbal plants are rich sources of secondary metabolites such as phenolics which can be beneficial to improve human health. Previous studies reported that phenolic compounds could lower the risk of heart diseases, occurrence of cancers as well as microbial infections. Piper sarmentosum or locally known as Kaduk is a tropical herb plant that is well established for many traditional medicinal purposes. These benefits may depend significantly on the phenolic content. Hence, the identification of phenolic compounds in this plant is necessary. The objective of the present study was to identify the phenolic compounds in crude methanolic extract of Piper sarmentosum leaves. Total phenolic content was determined spectrometrically according to Folin-Ciocalteu procedures. The characterization of the phenolic compounds was examined using reverse phase HPLC and GC-MS analyses. The total phenolic content was found to be 142.72 mg[GAE]/g of the Kaduk leaves extract. The presences of gallic acid, tannic acid, quercetin and naringenin were identified from the RP-HPLC analysis. From GC-MS analysis, the presences of elemicine, myristicine, methyleugenol and hydrocinnamic acid were revealed. Our findings provided the evidence that crude methanolic extract of Piper sarmentosum leaves contains high content of active phenolic compounds that might have the potential to be incorporated as the basis ingredient in medicines to treat various diseases in Malaysia.
format	Conference or Workshop Item
author	Mustafa, Farah Farisha Ibrahim, Maizatul Akma Mohamad, Habsah
author_facet	Mustafa, Farah Farisha Ibrahim, Maizatul Akma Mohamad, Habsah
author_sort	Mustafa, Farah Farisha
title	Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves
title_short	Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves
title_full	Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves
title_fullStr	Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves
title_full_unstemmed	Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves
title_sort	identification of phenolic compounds in crude methanolic extract of piper sarmentosum leaves
publishDate	2017
url	http://irep.iium.edu.my/71451/ http://irep.iium.edu.my/71451/7/71451%20programme.pdf
first_indexed	2023-09-18T21:41:19Z
last_indexed	2023-09-18T21:41:19Z
_version_	1777413159205732352

Identification of phenolic compounds in crude methanolic extract of Piper sarmentosum leaves

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